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经导管主动脉瓣置换术患者清醒镇静与气管插管全麻手术结局和安全性比较分析
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作者 王轶芃 周程辉 刘达琪 《中国循证心血管医学杂志》 2024年第5期538-542,共5页
目的比较经导管主动脉瓣置换术(Transcatheter Aortic Valve Implantation,TAVR)患者清醒镇静与气管插管全麻下手术结局和安全性方面的差异。方法选择2020年3月至2022年5月于首都医科大学附属北京安贞医院麻醉中心接受经股动脉TAVR治疗... 目的比较经导管主动脉瓣置换术(Transcatheter Aortic Valve Implantation,TAVR)患者清醒镇静与气管插管全麻下手术结局和安全性方面的差异。方法选择2020年3月至2022年5月于首都医科大学附属北京安贞医院麻醉中心接受经股动脉TAVR治疗的104例重度主动脉瓣狭窄(Aortic Stenosis,AS)患者进行回顾性分析。根据麻醉方式将患者分为清醒镇静组和插管麻醉组。在TAVR后1个月、6个月和12个月,使用健康状况调查问卷(the MOS item short fromhealth survey,SF-36)和欧洲五维度健康量表(European five-dimension Health Scale,EuroQol-5D)以及巴塞尔指数评定量表评估患者生活质量和自理能力。围手术期结局包括术后谵妄(Postoperative Delirium,POD)发生率和重症监护病房(ICU)住院天数。安全性结局定义为死亡、卒中、短暂性脑缺血发作、急性心肌梗死、需要透析、重大血管并发症、重大或危及生命的出血和需要永久性起搏器植入的复合事件。结果与插管麻醉组相比,清醒镇静组患者围手术期POD发生率显著降低,ICU住院时间显著缩短,差异有统计学意义(P<0.05)。清醒镇静组和插管麻醉组在术后SF-36评分、EuroQol-5D评分和Barthel量表评分等方面均无显著差异(P>0.05)。两组术后安全性复合结局比较,差异无统计学意义(P>0.05)。结论与气管插管全身麻醉相比,清醒镇静TAVR可减少POD和ICU住院时间,不影响安全性和患者生活质量。清醒镇静下TAVR对于AS患者是一种安全、有效的手术方式,是全身麻醉的可接受替代方案。 展开更多
关键词 经导管主动脉瓣置换术 全身麻醉 手术结局 安全性
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Characteristics of Energy Accumulation and Release of Seismogenic Tectonics and Seismic Risk Analysis in Some Areas in the Tianshan Mountains, Xinjiang
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作者 ShenJun LiYingzhen wangyipeng 《Earthquake Research in China》 2005年第1期1-11,共11页
Comparative analysis between the quantitative data of active faults and seismicity reveals that a complete earthquake recurrence cycle includes the characteristic earthquake and the sub-maxima earthquakes in-between. ... Comparative analysis between the quantitative data of active faults and seismicity reveals that a complete earthquake recurrence cycle includes the characteristic earthquake and the sub-maxima earthquakes in-between. The magnitude of the sub-maxima events is correlated with the elapsed time of the characteristic earthquake and the slip rate of the fault. The fault displacement includes the major stick-slip generated by the characteristic earthquakes and the minor stick-slip by the sub-maxima ones. The magnitude-frequency relationship still works in the complete recurrence cycle. The energy accumulation in the cycle is divided approximately into four phases, and the seismicity differs at each phase. The relation of the maximum displacement with the average displacement of the characteristic earthquake suggests the partitioning of deformation between the characteristic and the sub-maxima earthquakes. Based on the above analysis, relevant mathematical equations are put forward for the quantitative assessment of the potential magnitude and earthquake risk of seismogenic tectonics. Tentative study has been carried out in this aspect in some areas of Tianshan. 展开更多
关键词 seismogenic tectonics energy accumulation and release seismic riskanalysis TIANSHAN
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