An efficient and facile method for synthesis of 2-arylpyrroles through Rh（III）-catalyzed direct C--H arylation with pyrrole derivatives and aryl boronic acids has been developed. This reaction could proceed under mi...An efficient and facile method for synthesis of 2-arylpyrroles through Rh（III）-catalyzed direct C--H arylation with pyrrole derivatives and aryl boronic acids has been developed. This reaction could proceed under mild reaction conditions and afford a series of 2-arylated products in good to excellent yields. The gram-scale experiment has been conducted to demonstrate the synthetic potential of this methodology.展开更多
基金We are grateful to the National Natural Science Foundation of China （No. 21302064） and Scientific Research Project of Hubei Provincial Department of Education （No. 2015231） for support of this research.
文摘An efficient and facile method for synthesis of 2-arylpyrroles through Rh（III）-catalyzed direct C--H arylation with pyrrole derivatives and aryl boronic acids has been developed. This reaction could proceed under mild reaction conditions and afford a series of 2-arylated products in good to excellent yields. The gram-scale experiment has been conducted to demonstrate the synthetic potential of this methodology.
