A case of life-threatening lower gastrointestinal hemorrhage from Crohn’s disease is reported. Several promising studies have recently been published that describe super selective embolization for the treatment of ma...A case of life-threatening lower gastrointestinal hemorrhage from Crohn’s disease is reported. Several promising studies have recently been published that describe super selective embolization for the treatment of massive lower gastrointestinal hemorrhage in patients with bleeding colonic diverticular disease and angiodysplasia, and success rates of 74%-93%have been reported. But in patients with Crohn’s disease, successful superselective embolization has rarely been reported. This is a report of successful superselective embolization in a patient with Crohn’s disease; this should be the initial treatment of choice in Crohn‘s disease in an attempt to avoid surgical resection, because repeated resections predispose patients to the development of short-bowel syndrome.展开更多
Background: TrUeatments of port-wine stains with conventional pulsed dye laser yield inconsistent results. Objective: We evaluated the efficacy and safety of the longer pulse duration 595-nm dye laser. Methods: Sixty-...Background: TrUeatments of port-wine stains with conventional pulsed dye laser yield inconsistent results. Objective: We evaluated the efficacy and safety of the longer pulse duration 595-nm dye laser. Methods: Sixty-six adult Japanese patients were enrolled in this prospective study. The laser treatment with a cooling device was repeated 4 times at 8-week intervals with a consistent setting of 10-ms pulse duration and an energy fluence of 12 J/cm2, using 7-mm spot size. Results: Improvement of port-wine stains was observed after multiple treatments, and 67% of the patients achieved either good or excellent response after the fourth treatment. Transient purpura, edema, or both were noted immediately after each treatment (76% -79% and 58% -67% , respectively). Hyperpigmentation (8% -17% ) and hypopigmentation (6% -14% ) were also mild and their occurrence did not increase by repeating treatments. Limitations: Eighty five percent of the patients were classified as having Fitzpatrick skin type IV. Conclusion: Our study indicated that the 595-nm dye laser with 10-ms pulse duration may be effective and well tolerated in the treatment of port-wine stains in adult Asians.展开更多
文摘A case of life-threatening lower gastrointestinal hemorrhage from Crohn’s disease is reported. Several promising studies have recently been published that describe super selective embolization for the treatment of massive lower gastrointestinal hemorrhage in patients with bleeding colonic diverticular disease and angiodysplasia, and success rates of 74%-93%have been reported. But in patients with Crohn’s disease, successful superselective embolization has rarely been reported. This is a report of successful superselective embolization in a patient with Crohn’s disease; this should be the initial treatment of choice in Crohn‘s disease in an attempt to avoid surgical resection, because repeated resections predispose patients to the development of short-bowel syndrome.
文摘Background: TrUeatments of port-wine stains with conventional pulsed dye laser yield inconsistent results. Objective: We evaluated the efficacy and safety of the longer pulse duration 595-nm dye laser. Methods: Sixty-six adult Japanese patients were enrolled in this prospective study. The laser treatment with a cooling device was repeated 4 times at 8-week intervals with a consistent setting of 10-ms pulse duration and an energy fluence of 12 J/cm2, using 7-mm spot size. Results: Improvement of port-wine stains was observed after multiple treatments, and 67% of the patients achieved either good or excellent response after the fourth treatment. Transient purpura, edema, or both were noted immediately after each treatment (76% -79% and 58% -67% , respectively). Hyperpigmentation (8% -17% ) and hypopigmentation (6% -14% ) were also mild and their occurrence did not increase by repeating treatments. Limitations: Eighty five percent of the patients were classified as having Fitzpatrick skin type IV. Conclusion: Our study indicated that the 595-nm dye laser with 10-ms pulse duration may be effective and well tolerated in the treatment of port-wine stains in adult Asians.
