AIM:To identify risk factors of recurrence of this disorder after intravitreal ranibizumab(IVR)monotherapy.METHODS:Totally 33 eyes of 19 patients who underwent initial IVR treatments for type 1 retinopathy of prematur...AIM:To identify risk factors of recurrence of this disorder after intravitreal ranibizumab(IVR)monotherapy.METHODS:Totally 33 eyes of 19 patients who underwent initial IVR treatments for type 1 retinopathy of prematurity(ROP)at our center were retrospectively reviewed between April 1,2016 and December 31,2017.Patient demographics,the side of ROP,multiple gestations,Apgar scores,zone,stage,plus disease,postmenstrual age at injection,surfactant therapy,blood transfusion therapy,hemorrhage before IVR,hemorrhage after IVR,gestational diabetes mellitus,pregnancy-induced hypertension,anemia,intraventricular hemorrhage,sepsis,respiratory distress syndrome,carbohemia,and congenital heart defects were recorded.Adjusted hazard ratios(HRs)and 95%confidence intervals were determined after adjusting for potential confounders using multivariate proportional Cox regression.RESULTS:Of the 33 eyes,12(36.4%)had ROP recurrences 45.3(5.1,50.9)mo after initial IVR treatments.The independent risk factors for ROP recurrences were zone(ⅡvsⅠ,HR:0.056,P=0.003)and gestational diabetes mellitus(no vs yes,HR:0.095,P<0.001).The mean uncorrected visual acuity for four recurrence eyes was 0.46 logMAR(0.13,0.70)at 55.0(51.0,58.9)mo after the initial IVR treatment.The mean uncorrected visual acuity for 10 eyes without recurrence was 0.46 logMAR(0.19,0.63)at 48.0(43.8,58.4)mo after the initial IVR treatment.CONCLUSION:Two independent risk factors for type 1 ROP recurrence after IVR treatment involving zoneⅠand gestational diabetes mellitus are identified,and the mean uncorrected visual acuity is 0.46 logMAR at 51.0(44.0,58.9)mo.The findings of this study are important for followup management and for improving the visual function of ROP patients.展开更多
Electronic warfare is a modern combat mode,in which predicting digital material consumption is a key for material requirements planning(MRP).In this paper,we introduce an insensitive loss function(ε) and propose a ε...Electronic warfare is a modern combat mode,in which predicting digital material consumption is a key for material requirements planning(MRP).In this paper,we introduce an insensitive loss function(ε) and propose a ε-SVR-based prediction approach.First,we quantify values of influencing factors of digital equipments in electronic warfare and a small-sample data on real consumption to form a real combat data set,and preprocess it to construct the sample space.Subsequently,we establish the ε-SVR-based prediction model based on "wartime influencing factors-material consumption" and perform model training.In case study,we give 8 historical battle events with battle damage data and predict 3 representative kinds of digital materials by using the proposed approach.The results illustrate its higher accuracy and more convenience compared with other current approaches.Taking data acquisition controller prediction as an example,our model has better prediction performance(RMSE=0.575 7,MAPE(%)=12.037 6 and R^2=0.996 0) compared with BP neural network model(RMSE=1.272 9,MAPE(%)=23.577 5 and R^2=0.980 3) and GM(1,1) model(RMSE=2.095 0,MAPE(%)=24.188 0 and R^2=0.946 6).The fact shows that the approach can be used to support decision-making for MRP in electronic warfare.展开更多
Modeling influencing factors of battle damage is one of essential works in implementing military industrial logistics simulation to explore battle damage laws knowledge.However,one of key challenges in designing the s...Modeling influencing factors of battle damage is one of essential works in implementing military industrial logistics simulation to explore battle damage laws knowledge.However,one of key challenges in designing the simulation system could be how to reasonably determine simulation model input and build a bridge to link battle damage model and battle damage laws knowledge.In this paper,we propose a novel knowledge-oriented modeling method for influencing factors of battle damage in military industrial logistics,integrating conceptual analysis,conceptual modeling,quantitative modeling and simulation implementation.We conceptualize influencing factors of battle damage by using the principle of hierarchical decomposition,thus classifying the related battle damage knowledge logically.Then,we construct the conceptual model of influencing factors of battle damage by using Entity-Relations hip approach,thus describing their interactions reasonably.Subsequently,we extract the important influencing factors by using social network analysis,thus evaluating their importance quantitatively and further clarifying the elements of simulation.Finally,we develop an agent-based military industry logistics simulation system by taking the modeling results on influencing factors of battle damage as simulation model input,and obtain simulation model output,i.e.,new battle damage laws knowledge,thus verifying feasibility and effectiveness of the proposed method.The results show that this method can be used to support human decision-making and action.展开更多
In recent years, the incidence of severe infectious diseases has increased, and the number of emerging infectious diseases continues to increase. The Chinese government and military forces have paid a great deal of at...In recent years, the incidence of severe infectious diseases has increased, and the number of emerging infectious diseases continues to increase. The Chinese government and military forces have paid a great deal of attention to infectious disease prevention and control, and using military-civilian cooperation, they have successfully prevented numerous severe epidemic situations, such as severe acute respiratory syndrome(SARS), influenza A(H1N1), avian influenza H5N1 and H7N9, and Ebola hemorrhagic fever, while actively maintained public health, economic development, and national construction. This paper focuses on the mechanisms of the military-cooperative emergency response to infectious diseases–the joint working mechanism, the information-sharing mechanism, the research collaboration mechanism, and the joint disposal mechanism–and presents a sorted summary of the practices and experiences of cooperative emergency responses to infectious diseases. In the future, the Chinese military and the civilian sector will further strengthen the cooperative joint command system and emergency rescue force and will reinforce their collaborative information-sharing platform and technical equipment system to further improve military-civilian collaborative emergency infectious diseases disposal, advance the level of infectious disease prevention and control, and maintain public health.展开更多
Purpose:Our aim was to obtain a better understanding of the etiologies and characteristics of pediatric cataracts treated at a single facility in China.Methods:.Medical records accrued over a 10-year period(from Augus...Purpose:Our aim was to obtain a better understanding of the etiologies and characteristics of pediatric cataracts treated at a single facility in China.Methods:.Medical records accrued over a 10-year period(from August, 2003 to July, 2013) at Shengjing Hospital of China Medical University were reviewed retrospectively,ide ntifying all patients treated for various subtypes of pediatric cataract..A database with 367 subjects under 14 years of age(598, including second-round surgeries) was generated.Results:.Of this cohort(n =367; males: 232, 63.2%; females: 135, 36.8%), 200 patients(54.5%) had bilateral cataracts,and 258(70.3%) were under 3 years of age. In all age groups and in all subtypes of pediatric cataract,.males were most commonly affected..Congenital cataract was the most prevalent subtype, accounting for 296 patients(80.7%). Most congenital cataracts were associated with other ocular or systemic abnormalities;.and in 48 patients(16.22%),.they were hereditary..Traumatic cataract was the most common subtype(85.92%) of acquired cataract. The few instances of cataracts due to steroids(n=3) or to metabolic disorders(n=2) occurred in males and involved both eyes.Conclusion: The majority of pediatric cataracts in this patient population were congenital in nature. A significant lag in ophthalmologic evaluation of Chinese infants was evident and should be addressed by educating both children and parents on risk factors for cataract development. Regular assessments are especially important in children subjected to long-term systemic steroid treatments.展开更多
文摘AIM:To identify risk factors of recurrence of this disorder after intravitreal ranibizumab(IVR)monotherapy.METHODS:Totally 33 eyes of 19 patients who underwent initial IVR treatments for type 1 retinopathy of prematurity(ROP)at our center were retrospectively reviewed between April 1,2016 and December 31,2017.Patient demographics,the side of ROP,multiple gestations,Apgar scores,zone,stage,plus disease,postmenstrual age at injection,surfactant therapy,blood transfusion therapy,hemorrhage before IVR,hemorrhage after IVR,gestational diabetes mellitus,pregnancy-induced hypertension,anemia,intraventricular hemorrhage,sepsis,respiratory distress syndrome,carbohemia,and congenital heart defects were recorded.Adjusted hazard ratios(HRs)and 95%confidence intervals were determined after adjusting for potential confounders using multivariate proportional Cox regression.RESULTS:Of the 33 eyes,12(36.4%)had ROP recurrences 45.3(5.1,50.9)mo after initial IVR treatments.The independent risk factors for ROP recurrences were zone(ⅡvsⅠ,HR:0.056,P=0.003)and gestational diabetes mellitus(no vs yes,HR:0.095,P<0.001).The mean uncorrected visual acuity for four recurrence eyes was 0.46 logMAR(0.13,0.70)at 55.0(51.0,58.9)mo after the initial IVR treatment.The mean uncorrected visual acuity for 10 eyes without recurrence was 0.46 logMAR(0.19,0.63)at 48.0(43.8,58.4)mo after the initial IVR treatment.CONCLUSION:Two independent risk factors for type 1 ROP recurrence after IVR treatment involving zoneⅠand gestational diabetes mellitus are identified,and the mean uncorrected visual acuity is 0.46 logMAR at 51.0(44.0,58.9)mo.The findings of this study are important for followup management and for improving the visual function of ROP patients.
基金funded by National Natural Science Foundation of China(grant number 61473311,70901075)Natural Science Foundation of Beijing Municipality(grant number 9142017)military projects funded by the Chinese Army。
文摘Electronic warfare is a modern combat mode,in which predicting digital material consumption is a key for material requirements planning(MRP).In this paper,we introduce an insensitive loss function(ε) and propose a ε-SVR-based prediction approach.First,we quantify values of influencing factors of digital equipments in electronic warfare and a small-sample data on real consumption to form a real combat data set,and preprocess it to construct the sample space.Subsequently,we establish the ε-SVR-based prediction model based on "wartime influencing factors-material consumption" and perform model training.In case study,we give 8 historical battle events with battle damage data and predict 3 representative kinds of digital materials by using the proposed approach.The results illustrate its higher accuracy and more convenience compared with other current approaches.Taking data acquisition controller prediction as an example,our model has better prediction performance(RMSE=0.575 7,MAPE(%)=12.037 6 and R^2=0.996 0) compared with BP neural network model(RMSE=1.272 9,MAPE(%)=23.577 5 and R^2=0.980 3) and GM(1,1) model(RMSE=2.095 0,MAPE(%)=24.188 0 and R^2=0.946 6).The fact shows that the approach can be used to support decision-making for MRP in electronic warfare.
基金This research was funded by National Natural Science Foundation of China(grant number 61473311,70901075)Natural Science Foundation of Beijing Municipality(grant number 9142017)military projects funded by the Chinese Army.
文摘Modeling influencing factors of battle damage is one of essential works in implementing military industrial logistics simulation to explore battle damage laws knowledge.However,one of key challenges in designing the simulation system could be how to reasonably determine simulation model input and build a bridge to link battle damage model and battle damage laws knowledge.In this paper,we propose a novel knowledge-oriented modeling method for influencing factors of battle damage in military industrial logistics,integrating conceptual analysis,conceptual modeling,quantitative modeling and simulation implementation.We conceptualize influencing factors of battle damage by using the principle of hierarchical decomposition,thus classifying the related battle damage knowledge logically.Then,we construct the conceptual model of influencing factors of battle damage by using Entity-Relations hip approach,thus describing their interactions reasonably.Subsequently,we extract the important influencing factors by using social network analysis,thus evaluating their importance quantitatively and further clarifying the elements of simulation.Finally,we develop an agent-based military industry logistics simulation system by taking the modeling results on influencing factors of battle damage as simulation model input,and obtain simulation model output,i.e.,new battle damage laws knowledge,thus verifying feasibility and effectiveness of the proposed method.The results show that this method can be used to support human decision-making and action.
基金supported by the National Social Science Foundation of China(15003–155)
文摘In recent years, the incidence of severe infectious diseases has increased, and the number of emerging infectious diseases continues to increase. The Chinese government and military forces have paid a great deal of attention to infectious disease prevention and control, and using military-civilian cooperation, they have successfully prevented numerous severe epidemic situations, such as severe acute respiratory syndrome(SARS), influenza A(H1N1), avian influenza H5N1 and H7N9, and Ebola hemorrhagic fever, while actively maintained public health, economic development, and national construction. This paper focuses on the mechanisms of the military-cooperative emergency response to infectious diseases–the joint working mechanism, the information-sharing mechanism, the research collaboration mechanism, and the joint disposal mechanism–and presents a sorted summary of the practices and experiences of cooperative emergency responses to infectious diseases. In the future, the Chinese military and the civilian sector will further strengthen the cooperative joint command system and emergency rescue force and will reinforce their collaborative information-sharing platform and technical equipment system to further improve military-civilian collaborative emergency infectious diseases disposal, advance the level of infectious disease prevention and control, and maintain public health.
基金National Natural Science Foundation of China(No.30973276)
文摘Purpose:Our aim was to obtain a better understanding of the etiologies and characteristics of pediatric cataracts treated at a single facility in China.Methods:.Medical records accrued over a 10-year period(from August, 2003 to July, 2013) at Shengjing Hospital of China Medical University were reviewed retrospectively,ide ntifying all patients treated for various subtypes of pediatric cataract..A database with 367 subjects under 14 years of age(598, including second-round surgeries) was generated.Results:.Of this cohort(n =367; males: 232, 63.2%; females: 135, 36.8%), 200 patients(54.5%) had bilateral cataracts,and 258(70.3%) were under 3 years of age. In all age groups and in all subtypes of pediatric cataract,.males were most commonly affected..Congenital cataract was the most prevalent subtype, accounting for 296 patients(80.7%). Most congenital cataracts were associated with other ocular or systemic abnormalities;.and in 48 patients(16.22%),.they were hereditary..Traumatic cataract was the most common subtype(85.92%) of acquired cataract. The few instances of cataracts due to steroids(n=3) or to metabolic disorders(n=2) occurred in males and involved both eyes.Conclusion: The majority of pediatric cataracts in this patient population were congenital in nature. A significant lag in ophthalmologic evaluation of Chinese infants was evident and should be addressed by educating both children and parents on risk factors for cataract development. Regular assessments are especially important in children subjected to long-term systemic steroid treatments.
