Two bioactive natural 4-arylcoumarins,5,7,4＇-trimethoxy-4-phenylcoumarin（1a）,5,7-dimethoxy-4-phenylcoumarin（1b） and five closely related derivatives 1c-g were synthesized.In vitro evaluation with a catechol subun...Two bioactive natural 4-arylcoumarins,5,7,4＇-trimethoxy-4-phenylcoumarin（1a）,5,7-dimethoxy-4-phenylcoumarin（1b） and five closely related derivatives 1c-g were synthesized.In vitro evaluation with a catechol subunit for antioxidant and antimicrobial activity,these compounds using standard methods showed that compounds 1d,1f displayed promise radical scavenging activity and 1f was found to be the most active one against Bacillus dysenteriae.展开更多
基金We thank the Science and Technology Program of Guangdong Province,Strategic Cooperation Program between Guangdong Province and Chinese Academy of Sciences and National Key Technology R&D Program,China(Nos. 2003B31603,2006B35604002,2009B091300125 and 2007BAD82B02) for financial support
文摘Two bioactive natural 4-arylcoumarins,5,7,4＇-trimethoxy-4-phenylcoumarin（1a）,5,7-dimethoxy-4-phenylcoumarin（1b） and five closely related derivatives 1c-g were synthesized.In vitro evaluation with a catechol subunit for antioxidant and antimicrobial activity,these compounds using standard methods showed that compounds 1d,1f displayed promise radical scavenging activity and 1f was found to be the most active one against Bacillus dysenteriae.
