At present,China is facing new strategic opportunities as well as risks and challenges in its development.Faced with the challenges brought by current global major risks,China urgently needs to build a group of world-...At present,China is facing new strategic opportunities as well as risks and challenges in its development.Faced with the challenges brought by current global major risks,China urgently needs to build a group of world-class enterprises as ballast stones.Accelerating the development of a number of world-class enterprises is an important support for China to enhance its comprehensive strength and international competitiveness,and is crucial for the realization of the strategic blueprint for socialist modernization.After more than forty years of reform and opening up,Chinese enterprises have rapidly developed and grown stronger,with their position rising and their influence in the global market increasing continuously.However,Chinese enterprises are“large in size but not yet strong enough”.In this context,this paper systematically analyzes the practical significance and theoretical connotation of building world-class enterprises and the status quo of building world-class enterprises in China and takes CNOOC as an example to deeply analyze the practices of large central enterprises to build world-class enterprises at the levels of group and subsidiaries,providing a reference for Chinese enterprises to accelerate their progress towards world-class enterprises.展开更多
目的探讨电流感觉阈值(CPT)测定对三叉神经痛患者感觉定量的评估作用。方法选择2017年1月—2018年10月江西省人民医院神经内科住院部或门诊临床确诊为原发性三叉神经痛下颌支受累的患者26例,所有患者均常规给予营养神经的药物治疗。在...目的探讨电流感觉阈值(CPT)测定对三叉神经痛患者感觉定量的评估作用。方法选择2017年1月—2018年10月江西省人民医院神经内科住院部或门诊临床确诊为原发性三叉神经痛下颌支受累的患者26例,所有患者均常规给予营养神经的药物治疗。在治疗前、治疗后7、14 d对患者进行CPT测定和简化麦吉尔(McGill)疼痛问卷评分表(SF-MPQ)测评,比较CPT和SF-MPQ疼痛评分,评价CPT在三叉神经痛患者治疗前后的感觉功能中的应用价值。结果治疗前用5、250 Hz刺激,患侧CPT高于健侧,差异均有统计学意义(均P<0.05),而用2000 Hz刺激,两侧CPT比较,差异无统计学意义(P>0.05)。患侧治疗后7、14 d CPT与治疗前比较,5、250 Hz刺激下的CPT均有所下降,差异均有统计学意义(均P<0.05),而2000 Hz刺激下患侧治疗后7、14 d CPT与治疗前比较,差异无统计学意义(P>0.05)。治疗后7、14 d SF-MPQ疼痛评分低于治疗前,差异均有统计学意义(均P<0.05)。Pearson相关分析显示,治疗前,治疗后7、14 d的SF-MPQ疼痛评分与患侧下颌支5 Hz刺激下CPT呈正相关(r=0.656、0.418、0.697,P<0.05)。结论CPT可量化地检测三叉神经痛患者治疗前后的感觉功能,客观地评估治疗前后病情程度及治疗效果。展开更多
酰胺键是一种可表现出高生理活性的特殊结构,形成酰胺最理想的途径是羧酸与胺直接反应,但必须要在强热的条件下才可生成。为了解决此问题,研究了一种通过利用简单的芳基硼酸催化,在较为缓和的条件下使脂肪酸与伯胺直接缩合构建酰胺的方...酰胺键是一种可表现出高生理活性的特殊结构,形成酰胺最理想的途径是羧酸与胺直接反应,但必须要在强热的条件下才可生成。为了解决此问题,研究了一种通过利用简单的芳基硼酸催化,在较为缓和的条件下使脂肪酸与伯胺直接缩合构建酰胺的方法,以苯乙酸与苄胺的直接酰胺化建立反应体系,对反应催化剂种类、催化剂用量、反应溶剂、反应时间以及反应温度进行了优化。结果表明:以氟苯为溶剂,苯硼酸为催化剂,先在回流温度下处理有机酸1h后,再加入脂肪胺继续反应12h,在此最佳反应条件下,可获得对应酰胺的收率在80%以上,采用1 H NMR和13C NMR对所得产物的结构进行了表征。方法操作简单,产物易于纯化,是一种新的制备酰胺类化合物的有效方法。展开更多
文摘At present,China is facing new strategic opportunities as well as risks and challenges in its development.Faced with the challenges brought by current global major risks,China urgently needs to build a group of world-class enterprises as ballast stones.Accelerating the development of a number of world-class enterprises is an important support for China to enhance its comprehensive strength and international competitiveness,and is crucial for the realization of the strategic blueprint for socialist modernization.After more than forty years of reform and opening up,Chinese enterprises have rapidly developed and grown stronger,with their position rising and their influence in the global market increasing continuously.However,Chinese enterprises are“large in size but not yet strong enough”.In this context,this paper systematically analyzes the practical significance and theoretical connotation of building world-class enterprises and the status quo of building world-class enterprises in China and takes CNOOC as an example to deeply analyze the practices of large central enterprises to build world-class enterprises at the levels of group and subsidiaries,providing a reference for Chinese enterprises to accelerate their progress towards world-class enterprises.
文摘目的探讨电流感觉阈值(CPT)测定对三叉神经痛患者感觉定量的评估作用。方法选择2017年1月—2018年10月江西省人民医院神经内科住院部或门诊临床确诊为原发性三叉神经痛下颌支受累的患者26例,所有患者均常规给予营养神经的药物治疗。在治疗前、治疗后7、14 d对患者进行CPT测定和简化麦吉尔(McGill)疼痛问卷评分表(SF-MPQ)测评,比较CPT和SF-MPQ疼痛评分,评价CPT在三叉神经痛患者治疗前后的感觉功能中的应用价值。结果治疗前用5、250 Hz刺激,患侧CPT高于健侧,差异均有统计学意义(均P<0.05),而用2000 Hz刺激,两侧CPT比较,差异无统计学意义(P>0.05)。患侧治疗后7、14 d CPT与治疗前比较,5、250 Hz刺激下的CPT均有所下降,差异均有统计学意义(均P<0.05),而2000 Hz刺激下患侧治疗后7、14 d CPT与治疗前比较,差异无统计学意义(P>0.05)。治疗后7、14 d SF-MPQ疼痛评分低于治疗前,差异均有统计学意义(均P<0.05)。Pearson相关分析显示,治疗前,治疗后7、14 d的SF-MPQ疼痛评分与患侧下颌支5 Hz刺激下CPT呈正相关(r=0.656、0.418、0.697,P<0.05)。结论CPT可量化地检测三叉神经痛患者治疗前后的感觉功能,客观地评估治疗前后病情程度及治疗效果。
文摘酰胺键是一种可表现出高生理活性的特殊结构,形成酰胺最理想的途径是羧酸与胺直接反应,但必须要在强热的条件下才可生成。为了解决此问题,研究了一种通过利用简单的芳基硼酸催化,在较为缓和的条件下使脂肪酸与伯胺直接缩合构建酰胺的方法,以苯乙酸与苄胺的直接酰胺化建立反应体系,对反应催化剂种类、催化剂用量、反应溶剂、反应时间以及反应温度进行了优化。结果表明:以氟苯为溶剂,苯硼酸为催化剂,先在回流温度下处理有机酸1h后,再加入脂肪胺继续反应12h,在此最佳反应条件下,可获得对应酰胺的收率在80%以上,采用1 H NMR和13C NMR对所得产物的结构进行了表征。方法操作简单,产物易于纯化,是一种新的制备酰胺类化合物的有效方法。
