This article investigates the characteristics of shock wave overpressure generated by multi-layer composite charge under different detonation modes.Combining dimensional analysis and the explosion mechanism of the cha...This article investigates the characteristics of shock wave overpressure generated by multi-layer composite charge under different detonation modes.Combining dimensional analysis and the explosion mechanism of the charge,a peak overpressure prediction model for the composite charge under singlepoint detonation and simultaneous detonation was established.The effects of the charge structure and initiation method on the overpressure field characteristics were investigated in AUTODYN simulation.The accuracy of the prediction model and the reliability of the numerical simulation method were subsequently verified in a series of static explosion experiments.The results reveal that the mass of the inner charge was the key factor determining the peak overpressure of the composite charge under single-point detonation.The peak overpressure in the radial direction improved apparently with an increase in the aspect ratio of the charge.The overpressure curves in the axial direction exhibited a multi-peak phenomenon,and the secondary peak overpressure even exceeded the primary peak at distances of 30D and 40D(where D is the charge diameter).The difference in peak overpressure among azimuth angles of 0-90°gradually decreased with an increase in the propagation distance of the shock wave.The coupled effect of the detonation energy of the inner and outer charge under simultaneous detonation improved the overpressure in both radial and axial directions.The difference in peak overpressure obtained from model prediction and experimental measurements was less than 16.4%.展开更多
The failure mechanism of a cylindrical shell cut into fragments by circumferential detonation collision was experimentally and numerically investigated.A self-designed detonation wave regulator was used to control the...The failure mechanism of a cylindrical shell cut into fragments by circumferential detonation collision was experimentally and numerically investigated.A self-designed detonation wave regulator was used to control the detonation and cut the shell.It was found that the self-designed regulator controlled the fragment shape.The macrostructure and micro-characteristics of fragments revealed that shear fracture was a prior mechanism,the shell fractured not only at the position of detonation collision,but the crack also penetrated the shell at the first contact position of the Chapmen-Jouguet(C-J)wave.The effects of groove number and outer layer thickness on the fracture behavior were tested by simulations.When the thickness of the outer layer was 5e18 mm,it has little effect on fragmentation of the shell,and shells all fractured at similar positions.The increase of the groove number reduced the fracture possibility of the first contact position of the C-J wave.When the groove number reached 7 with a 10 mm outer layer(1/4 model),the fracture only occurred at the position of detonation collision and the fragment width rebounded.展开更多
The numerical simulation of a blast wave of a multilayer composite charge is investigated.A calculation model of the near-field explosion and far-field propagation of the shock wave of a composite charge is establishe...The numerical simulation of a blast wave of a multilayer composite charge is investigated.A calculation model of the near-field explosion and far-field propagation of the shock wave of a composite charge is established using the AUTODYN finite element program.Results of the near-field and far-field calculations of the shock wave respectively converge at cell sizes of 0.25-0.5 cm and 1-3 cm.The Euler--fluxcorrected transport solver is found to be suitable for the far-field calculation after mapping.A numerical simulation is conducted to study the formation,propagation,and interaction of the shock wave of the composite charge for different initiation modes.It is found that the initiation mode obviously affects the shock-wave waveform and pressure distribution of the composite charge.Additionally,it is found that the area of the overpressure distribution is greatest for internal and external simultaneous initiation,and the peak pressure of the shock wave exponentially decays,fitting the calculation formula of the peak overpressure attenuation under different initiation modes,which is obtained and verified by experiment.The difference between numerical and experimental results is less than 10%,and the peak overpressure of both internal and external initiation is 56.12% higher than that of central single-point initiation.展开更多
The influe nce of initiation modes on the explosive dispersion process of the multi-layer co mposite charge(MCC) was studied.Overpressure sensors and high-speed photography system were used to investigate the energy r...The influe nce of initiation modes on the explosive dispersion process of the multi-layer co mposite charge(MCC) was studied.Overpressure sensors and high-speed photography system were used to investigate the energy release process of an MCC with a specific structure.The shock wave pressure and explosive dispersion characteristics of the MCC under different initiation modes were compared.The forming and expanding process of the shock wave of the composite charge under different initiation modes was determined.The separation position of the shock wave and fireball interface was determined.The calculation formulas of the shock radius and overpressure of the composite charge are presented.The radius of the shock wave of the composite charge was significantly affected by the initiation mode.Moreover,the development process of the composite explosive fireball under different initiation modes was analyzed,the variation rules of the composite charge dispersion radius and fireball dispersion velocity with time were obtained under the different initiation modes,the explosion energy release rate of composite charge under simultaneous initiation modes was the highest,and the peak overpressure under the simultaneous initiation mode was 1.61 times that of central single-point initiation.展开更多
In this study, 40 Cr Mn Si B steel cylindrical shells were tempered at 350, 500 and 600 ℃ to study the effect of tempering temperature on the dynamic process of expansion and fracture of the metal shell. A midexplosi...In this study, 40 Cr Mn Si B steel cylindrical shells were tempered at 350, 500 and 600 ℃ to study the effect of tempering temperature on the dynamic process of expansion and fracture of the metal shell. A midexplosion recovery experiment for the metal cylinder under internal explosive loading was designed, and the wreckage of the casings at the intermediate phase was obtained. The effects of different tempering temperatures on the macroscopic and microscopic fracture characteristics of 40 Cr Mn Si B steel were studied. The influence of tempering temperatures on the fracture characteristic parameters of the recovered wreckage were measured and analyzed, including the circumferential divide size, the thickness and the number of the circumferential divisions. The results show that as the tempering temperature was increased from 350 to 600 ℃, at first, the degree of fragmentation and the fracture characteristic parameters of the recovered wreckage changed significantly and then became essentially consistent. Scanning electron microscopy analysis revealed flow-like structure characteristics caused by adiabatic shear on different fracture surfaces. At the detonation initiation end of the casing, fracturing was formed by tearing along the crack, which existed a distance from the initiation end and propagated along the axis direction. In contrast, the fracturing near the middle position consists of a plurality of radial shear fracture units. The amount of alloy carbide that was precipitated during the tempering process increased continuously with tempering temperature, leading to an increasing number of spherical carbide particles scattered around the fracture surface.展开更多
A layered charge composed of the JH-2 explosive enveloped by a thick-walled cylindrical casing(active aluminum/rubber and inert lithium fluoride/rubber composites) was designed and explosion experiments were conducted...A layered charge composed of the JH-2 explosive enveloped by a thick-walled cylindrical casing(active aluminum/rubber and inert lithium fluoride/rubber composites) was designed and explosion experiments were conducted in a 1.3 m3tank and a 113 m3bunker.The blast parameters,including the quasistatic pressure(ΔpQS),special impulse(I),and peak overpressure(Δpmax),and images of the explosion process were recorded,and the influence of the Al content(30% and 50%) and Al particle size(1,10,and 50 μm) on the energy release of aluminum/rubber composites were investigated.The results revealed that the use of an active layer increased the peak overpressure generated by the primary blast wave,as well as the quasistatic pressure and special impulse related to fuel burning within tens of milliseconds after detonation.When the Al content was increased from 30% to 50%,the increases of ΔpQS and I were not obvious,and Δpmaxeven decreased,possibly because of decreased combustion efficiency and greater absorption of the blast wave energy for layers with 50% Al.Compared with the pure JH-2charge,the charge with 1 μm Al particles produced the highest Δpmax,indicating that better transient blast performance was generated by smaller Al particles.However,the charge with 10 μm Al particles showed the largest ΔpQSand I,suggesting that a stronger destructive effect occurred over a longer duration for charges that contained moderate 10 μm Al.展开更多
Aconventional procedure for treating hematospermia is to insert a ureteroscope or seminal vesiculoscope into the prostatic utr/de through the urethra, and then dilate the ejaculatory duct opening using the scope or th...Aconventional procedure for treating hematospermia is to insert a ureteroscope or seminal vesiculoscope into the prostatic utr/de through the urethra, and then dilate the ejaculatory duct opening using the scope or the catheter. However, the ejaculatory duct stenosis may occur after the simple ureteroscopy. We compared the outcomes of treating hematospermia using holmium laser incision through a ureteroscope and using simple ureteroscopy. Retrospective method was used to analyze 67 intractable hematospermia cases. Varying degrees of ejaculatory duct stenosis or obstruction were observed in all the patients. Postoperative follow-up was conducted for 6 months up to 3 years. Two patients who underwent the simple ureteroscopy experienced hematospermia recurrence in 6 and 8 months, respectively. No recurrence was found in all the patients who underwent the holmium laser incision. We have found that the holmium laser incision through a ureteroscope shows a better outcome than the simple ureteroscop~展开更多
This study aimed to evaluate the therapeutic effect of IR-61,a novel mitochondrial heptamethine cyanine dye with antioxidant effects,on diabetes mellitus-induced erectile dysfunction(DMED).Eight-week-old male Sprague-...This study aimed to evaluate the therapeutic effect of IR-61,a novel mitochondrial heptamethine cyanine dye with antioxidant effects,on diabetes mellitus-induced erectile dysfunction(DMED).Eight-week-old male Sprague-Dawley rats were intraperitoneally injected with streptozotocin(STZ)to induce type 1 diabetes.Eight weeks after STZ injection,all rats were divided into three groups:the control group,DM group,and DM+IR-61 group.In the DM+IR-61 group,the rats were administered IR-61(1.6 mg kg-1)twice a week by intravenous injection.At week 13,erectile function was evaluated by determining the ratio of the maximal intracavernous pressure to mean arterial pressure,and the penises were then harvested for fluorescent imaging,transmission electron microscopy,histological examinations,and Western blot analysis.Whole-body imaging suggested that IR-61 was highly accumulated in the penis after intravenous injection.IR-61 treatment significantly improved the maximal ICP of diabetic rats.Additionally,IR-61 ameliorated diabetes-induced inflammation,apoptosis,and phenotypic transition of corpus cavernosum smooth muscle cells(CCSMCs)in penile tissue.IR-61 also attenuated mitochondrial damage,reduced reactive oxygen species production in the corpus cavernosum and upregulated sirtuinl(SIRT1),sirtuin3(SIRT3),nuclear factor(erythroid-derived 2)-like 2(Nrf2),and heme oxygenase expression in penile tissue.In conclusion,IR-61 represents a potential therapeutic option for DMED by protecting the mitochondria of CCSMCs,which may be mediated by activation of the SIRT1,SIRT3,and Nrf2 pathways.展开更多
基金funded by the National Natural Science Foundation of China(Grant No.11972018,No.12002336)China Postdoctoral Science Foundation(Grant No.2021M701710)。
文摘This article investigates the characteristics of shock wave overpressure generated by multi-layer composite charge under different detonation modes.Combining dimensional analysis and the explosion mechanism of the charge,a peak overpressure prediction model for the composite charge under singlepoint detonation and simultaneous detonation was established.The effects of the charge structure and initiation method on the overpressure field characteristics were investigated in AUTODYN simulation.The accuracy of the prediction model and the reliability of the numerical simulation method were subsequently verified in a series of static explosion experiments.The results reveal that the mass of the inner charge was the key factor determining the peak overpressure of the composite charge under single-point detonation.The peak overpressure in the radial direction improved apparently with an increase in the aspect ratio of the charge.The overpressure curves in the axial direction exhibited a multi-peak phenomenon,and the secondary peak overpressure even exceeded the primary peak at distances of 30D and 40D(where D is the charge diameter).The difference in peak overpressure among azimuth angles of 0-90°gradually decreased with an increase in the propagation distance of the shock wave.The coupled effect of the detonation energy of the inner and outer charge under simultaneous detonation improved the overpressure in both radial and axial directions.The difference in peak overpressure obtained from model prediction and experimental measurements was less than 16.4%.
基金the National Natural Science Foundation of China No.11972018the Defense Pre-Research Joint Foundation of Chinese Ordnance Industry No.6141B012858.
文摘The failure mechanism of a cylindrical shell cut into fragments by circumferential detonation collision was experimentally and numerically investigated.A self-designed detonation wave regulator was used to control the detonation and cut the shell.It was found that the self-designed regulator controlled the fragment shape.The macrostructure and micro-characteristics of fragments revealed that shear fracture was a prior mechanism,the shell fractured not only at the position of detonation collision,but the crack also penetrated the shell at the first contact position of the Chapmen-Jouguet(C-J)wave.The effects of groove number and outer layer thickness on the fracture behavior were tested by simulations.When the thickness of the outer layer was 5e18 mm,it has little effect on fragmentation of the shell,and shells all fractured at similar positions.The increase of the groove number reduced the fracture possibility of the first contact position of the C-J wave.When the groove number reached 7 with a 10 mm outer layer(1/4 model),the fracture only occurred at the position of detonation collision and the fragment width rebounded.
基金funded by the National Natural Science Foundation of China under NO.11202103Qing-lan Project of Jiangsu Province。
文摘The numerical simulation of a blast wave of a multilayer composite charge is investigated.A calculation model of the near-field explosion and far-field propagation of the shock wave of a composite charge is established using the AUTODYN finite element program.Results of the near-field and far-field calculations of the shock wave respectively converge at cell sizes of 0.25-0.5 cm and 1-3 cm.The Euler--fluxcorrected transport solver is found to be suitable for the far-field calculation after mapping.A numerical simulation is conducted to study the formation,propagation,and interaction of the shock wave of the composite charge for different initiation modes.It is found that the initiation mode obviously affects the shock-wave waveform and pressure distribution of the composite charge.Additionally,it is found that the area of the overpressure distribution is greatest for internal and external simultaneous initiation,and the peak pressure of the shock wave exponentially decays,fitting the calculation formula of the peak overpressure attenuation under different initiation modes,which is obtained and verified by experiment.The difference between numerical and experimental results is less than 10%,and the peak overpressure of both internal and external initiation is 56.12% higher than that of central single-point initiation.
文摘The influe nce of initiation modes on the explosive dispersion process of the multi-layer co mposite charge(MCC) was studied.Overpressure sensors and high-speed photography system were used to investigate the energy release process of an MCC with a specific structure.The shock wave pressure and explosive dispersion characteristics of the MCC under different initiation modes were compared.The forming and expanding process of the shock wave of the composite charge under different initiation modes was determined.The separation position of the shock wave and fireball interface was determined.The calculation formulas of the shock radius and overpressure of the composite charge are presented.The radius of the shock wave of the composite charge was significantly affected by the initiation mode.Moreover,the development process of the composite explosive fireball under different initiation modes was analyzed,the variation rules of the composite charge dispersion radius and fireball dispersion velocity with time were obtained under the different initiation modes,the explosion energy release rate of composite charge under simultaneous initiation modes was the highest,and the peak overpressure under the simultaneous initiation mode was 1.61 times that of central single-point initiation.
基金funded by the National Natural Science Foundation of China (Grant No.11972018)sponsored by the Defense Pre-Research Joint Foundation of Chinese Ordnance Industry (Grant No. 6141B012858)。
文摘In this study, 40 Cr Mn Si B steel cylindrical shells were tempered at 350, 500 and 600 ℃ to study the effect of tempering temperature on the dynamic process of expansion and fracture of the metal shell. A midexplosion recovery experiment for the metal cylinder under internal explosive loading was designed, and the wreckage of the casings at the intermediate phase was obtained. The effects of different tempering temperatures on the macroscopic and microscopic fracture characteristics of 40 Cr Mn Si B steel were studied. The influence of tempering temperatures on the fracture characteristic parameters of the recovered wreckage were measured and analyzed, including the circumferential divide size, the thickness and the number of the circumferential divisions. The results show that as the tempering temperature was increased from 350 to 600 ℃, at first, the degree of fragmentation and the fracture characteristic parameters of the recovered wreckage changed significantly and then became essentially consistent. Scanning electron microscopy analysis revealed flow-like structure characteristics caused by adiabatic shear on different fracture surfaces. At the detonation initiation end of the casing, fracturing was formed by tearing along the crack, which existed a distance from the initiation end and propagated along the axis direction. In contrast, the fracturing near the middle position consists of a plurality of radial shear fracture units. The amount of alloy carbide that was precipitated during the tempering process increased continuously with tempering temperature, leading to an increasing number of spherical carbide particles scattered around the fracture surface.
基金funded by the National Natural Science Foundation of China(Grant No.11972018)the Defense Pre-Research Joint Foundation of Chinese Ordnance Industry(Grant No.6141B012858)。
文摘A layered charge composed of the JH-2 explosive enveloped by a thick-walled cylindrical casing(active aluminum/rubber and inert lithium fluoride/rubber composites) was designed and explosion experiments were conducted in a 1.3 m3tank and a 113 m3bunker.The blast parameters,including the quasistatic pressure(ΔpQS),special impulse(I),and peak overpressure(Δpmax),and images of the explosion process were recorded,and the influence of the Al content(30% and 50%) and Al particle size(1,10,and 50 μm) on the energy release of aluminum/rubber composites were investigated.The results revealed that the use of an active layer increased the peak overpressure generated by the primary blast wave,as well as the quasistatic pressure and special impulse related to fuel burning within tens of milliseconds after detonation.When the Al content was increased from 30% to 50%,the increases of ΔpQS and I were not obvious,and Δpmaxeven decreased,possibly because of decreased combustion efficiency and greater absorption of the blast wave energy for layers with 50% Al.Compared with the pure JH-2charge,the charge with 1 μm Al particles produced the highest Δpmax,indicating that better transient blast performance was generated by smaller Al particles.However,the charge with 10 μm Al particles showed the largest ΔpQSand I,suggesting that a stronger destructive effect occurred over a longer duration for charges that contained moderate 10 μm Al.
文摘Aconventional procedure for treating hematospermia is to insert a ureteroscope or seminal vesiculoscope into the prostatic utr/de through the urethra, and then dilate the ejaculatory duct opening using the scope or the catheter. However, the ejaculatory duct stenosis may occur after the simple ureteroscopy. We compared the outcomes of treating hematospermia using holmium laser incision through a ureteroscope and using simple ureteroscopy. Retrospective method was used to analyze 67 intractable hematospermia cases. Varying degrees of ejaculatory duct stenosis or obstruction were observed in all the patients. Postoperative follow-up was conducted for 6 months up to 3 years. Two patients who underwent the simple ureteroscopy experienced hematospermia recurrence in 6 and 8 months, respectively. No recurrence was found in all the patients who underwent the holmium laser incision. We have found that the holmium laser incision through a ureteroscope shows a better outcome than the simple ureteroscop~
基金the National Key Research and Development Program(2016Y FC1000805)University Innovation Team Building Program of Chongqing(CXTDG201602020)Science and Technology Research Program of Chongqing Municipal Education Commission(KJQN202000433).
文摘This study aimed to evaluate the therapeutic effect of IR-61,a novel mitochondrial heptamethine cyanine dye with antioxidant effects,on diabetes mellitus-induced erectile dysfunction(DMED).Eight-week-old male Sprague-Dawley rats were intraperitoneally injected with streptozotocin(STZ)to induce type 1 diabetes.Eight weeks after STZ injection,all rats were divided into three groups:the control group,DM group,and DM+IR-61 group.In the DM+IR-61 group,the rats were administered IR-61(1.6 mg kg-1)twice a week by intravenous injection.At week 13,erectile function was evaluated by determining the ratio of the maximal intracavernous pressure to mean arterial pressure,and the penises were then harvested for fluorescent imaging,transmission electron microscopy,histological examinations,and Western blot analysis.Whole-body imaging suggested that IR-61 was highly accumulated in the penis after intravenous injection.IR-61 treatment significantly improved the maximal ICP of diabetic rats.Additionally,IR-61 ameliorated diabetes-induced inflammation,apoptosis,and phenotypic transition of corpus cavernosum smooth muscle cells(CCSMCs)in penile tissue.IR-61 also attenuated mitochondrial damage,reduced reactive oxygen species production in the corpus cavernosum and upregulated sirtuinl(SIRT1),sirtuin3(SIRT3),nuclear factor(erythroid-derived 2)-like 2(Nrf2),and heme oxygenase expression in penile tissue.In conclusion,IR-61 represents a potential therapeutic option for DMED by protecting the mitochondria of CCSMCs,which may be mediated by activation of the SIRT1,SIRT3,and Nrf2 pathways.