Graphdiyne(GDY)is a new member of the family of carbon based nanomaterials with hybridized carbon atoms of sp and sp',including a,β,γ,and(6,6,12)-GDY,which difer in their percentage of acetylene bonds.The unique...Graphdiyne(GDY)is a new member of the family of carbon based nanomaterials with hybridized carbon atoms of sp and sp',including a,β,γ,and(6,6,12)-GDY,which difer in their percentage of acetylene bonds.The unique structure of GDY provides many attractive features,such as uniformly distributed pores,highlyπconjugated structure,high thermal stability,low toxicity,biod egradabilty,large specific surface area,tunable electrical conductivity,and remarkable thermal conductivity.Therefore,GDY is widely used in energy storage,catalysis,and energy fields,in addition to biomedical fields,such as biosensing,cancer therapy,drug delivery,radiation protection,and tissue engineering.In this review,we first discuss the synthesis of GDY with different shapes,including nanotubes,nanowires,nanowalls,and nanosheets.Second,we present the research progress in the biomedical field in recent years,along with the biodegradability and biocompatibility of GDY based on the existing literature.Subsequently,we present recent research results on the use of nanomaterials in peripheral nerve regeneration(PNR).Based on the wide application of nanomaterials in PNR and the remarkable properties of GDY,we.predict the prospects and current challenges of GDY-based materials for PNR.展开更多
基金supported by the National Key R&D Program of China(No.2021YFC2400801)Projects of National Natural Science Foundation of China(Nos.82002290,82072452,52072210,and 81830076)+4 种基金Young Elite Scientist Sponsorship Program by Cast(No.YESS20200153)Natural Science Foun-dation of Shanghai(No.19ZR1439200)Shanghai Municipal Health Commission Foundation(No.202040399)Medical-Engineering Co-Project of University of Shanghai for Science and Technology(10-22-310-520)Shanghai Sailing Pro-gram(No.20YF1436000).
文摘Graphdiyne(GDY)is a new member of the family of carbon based nanomaterials with hybridized carbon atoms of sp and sp',including a,β,γ,and(6,6,12)-GDY,which difer in their percentage of acetylene bonds.The unique structure of GDY provides many attractive features,such as uniformly distributed pores,highlyπconjugated structure,high thermal stability,low toxicity,biod egradabilty,large specific surface area,tunable electrical conductivity,and remarkable thermal conductivity.Therefore,GDY is widely used in energy storage,catalysis,and energy fields,in addition to biomedical fields,such as biosensing,cancer therapy,drug delivery,radiation protection,and tissue engineering.In this review,we first discuss the synthesis of GDY with different shapes,including nanotubes,nanowires,nanowalls,and nanosheets.Second,we present the research progress in the biomedical field in recent years,along with the biodegradability and biocompatibility of GDY based on the existing literature.Subsequently,we present recent research results on the use of nanomaterials in peripheral nerve regeneration(PNR).Based on the wide application of nanomaterials in PNR and the remarkable properties of GDY,we.predict the prospects and current challenges of GDY-based materials for PNR.
