Neurodegenerative disease is one of the serious diseases of the human nervous system.There is no effective way to treat neurodegenerative diseases.Flavors such as curcumin,coumarin,have attracted increasing attention ...Neurodegenerative disease is one of the serious diseases of the human nervous system.There is no effective way to treat neurodegenerative diseases.Flavors such as curcumin,coumarin,have attracted increasing attention due to having a beneficial therapeutic effect on Alzheimer's disease and Parkinson's disease.But the use of most drugs is limited in clinical treatment because of blood-brain barrier.The use of nano-drug carriers such as liposomes,polymer micelles,polymer nanoparticles and magnetic nanoparticles,which can carry drugs across the blood-brain barrier,has brought hope for the treatment of neurodegenerative diseases.展开更多
基金financially supported by the National High Technology Research and Development Program(No.2016YFA0200303)the National Natural Science Foundation of China(No.51373177,51573188,and 31522023)+2 种基金Beijing Municipal Science & Technology Commission(No.Z161100002616015)the Beijing Natural Science Foundation(No.2164071)the “Strategic Priority Research Program” of the Chinese Academy of Sciences(No.XDA09030301-3)
文摘Neurodegenerative disease is one of the serious diseases of the human nervous system.There is no effective way to treat neurodegenerative diseases.Flavors such as curcumin,coumarin,have attracted increasing attention due to having a beneficial therapeutic effect on Alzheimer's disease and Parkinson's disease.But the use of most drugs is limited in clinical treatment because of blood-brain barrier.The use of nano-drug carriers such as liposomes,polymer micelles,polymer nanoparticles and magnetic nanoparticles,which can carry drugs across the blood-brain barrier,has brought hope for the treatment of neurodegenerative diseases.