Multiorgan dysfunction syndrome due to high-dose cantharidin poisoning:A case report

BACKGROUND This report delves into the diagnostic and therapeutic journey undertaken by a patient with high-dose cantharidin poisoning and multiorgan dysfunction syndrome(MODS).Particular emphasis is placed on the comprehensive elucidation of the clinical manifestations of high-dose cantharidin poisoning,the intricate path to diagnosis,and the exploration of potential underlying mechanisms.CASE SUMMARY A patient taking 10 g of cantharidin powder orally subsequently developed MODS.The patient was treated with supportive care,fluid hydration and antibiotics,and hemoperfusion and hemofiltration therapy for 24 h and successfully recovered 8 d after hospital admission.Cantharidin poisoning can cause lifethreatening MODS and is rare clinically.This case underscores the challenge in diagnosis and highlights the need for early clinical differentiation to facilitate accurate assessment and prompt intervention.CONCLUSION This article has reported and analyzed the clinical data,diagnosis,treatment,and prognosis of a case of high-dose cantharidin poisoning resulting in MODS and reviewed the relevant literature to improve the clinical understanding of this rare condition.

燃煤烟气半干法脱氯的化学动力学模拟（英文）

目的:燃煤锅炉烟气中的HCl对环境、设备及脱硫系统有不利的影响,也是脱硫废水处理的难点。本文提出半干法脱氯技术,探讨其技术合理性,并研究不同因素对反应效率的影响,为进一步工程应用提供理论依据,实现燃煤烟气中HCl的脱除及脱硫废水零排放。创新点:1.提出半干法脱氯技术,将氯离子固化到飞灰中;2.脱氯后脱硫废水大幅减少,将脱硫废水作为碱基溶剂回喷到烟道中,实现脱硫废水零排放;3.建立良搅拌反应器(PSR)模型,探讨半干法脱氯过程的化学动力学反应机理与关键参数。方法:1.通过CHEMKIN构建PSR模型,模拟实际燃煤烟气组分下的半干法脱氯过程;2.通过敏感性分析,探讨SO_2与HCl之间的竞争关系(图8~10);3.通过单变量模拟,研究不同因素对反应效率的影响(图13~16)。结论:1.烟气中的SO_2对HCl的脱除存在较大竞争关系,但即使Na/Cl(摩尔比)为1时,HCl的反应效率依然可观。2.HCl的反应效率与Na/Cl呈正相关;综合考虑反应效率和运行成本,设置Na/Cl为5较为合理。3.SO_2浓度的小范围变化不会对HCl的反应效率造成显著影响。4.仅通过化学动力学模拟,烟气温度对HCl的反应效率影响不明显。5.烟气中酸性气体与NaOH在0.1 s内即可完成反应,在1 s左右达到平衡。