Application of PDCA Cycle in Hand Hygiene Management of Psychiatric Medical Staff

Objective:To study the application effect of the plan-do-check-act(PDCA)cycle management in the hand hygiene management of psychiatric medical staff.Methods:One hundred and twenty medical staff from a psychiatric hospital from May 2023 to December 2023 were selected and divided into two groups.The control group(May 2023 to August 2023)applied the conventional management model,and the observation group(September 2023 to December 2023)applied the PDCA cycle management.The hand hygiene compliance,hand hygiene knowledge,and hygiene qualifications were compared,including the amount of hand sanitizer used.Results:The proportion of medical staff’s hand hygiene compliance and hand hygiene knowledge mastery scores in the observation group were higher than those in the control group(P<0.05);the hand hygiene passing rate in the observation group was higher than that of the control group(P<0.05);the daily amount of hand sanitizer per patient bed and the amount of hand sanitizer used was higher than that of the control group(P<0.05).Conclusion:The PDCA cycle management model for psychiatric medical staff promoted the improvement of hand hygiene compliance and increased their hand hygiene qualifications.It is suitable for further popularization and application in future clinical practice.

Development and Characterization of 35 SNP Markers in the Fat Greenling Hexagrammos otakii

Hexagrammos otakii is an important kind of economic fish species in East Asia. However, wild H. otakii resources have declined sharply in recent years as a result of human disturbance and habitat destruction. Thus, it is crucial to protect the current resources of H. otakii. In this study, 35 novel single nucleotide polymorphism (SNP) markers were developed based on restriction-site associated DNA sequencing. The results showed that the observed heterozygosity and expected heterozygosity ranged from 0.1875 to 0.6562 and 0.2679 to 0.5079, respectively. The minor allele frequency ranged from 0.1875 to 0.4375. Polymorphic information content ranged from 0.229 to 0.375. Six SNPs were found to be deviated significantly from the HWE (P H. otakii.

纤维素基水凝胶的构建及其应用

水凝胶是一种交联的三维网状亲水性聚合物材料,能够吸收和保留大量的水并且保持一定形状。近年来,随着石油资源的枯竭和人类对环境问题的日益关注,天然或改性类高分子合成聚合物水凝胶已成为研究的热点。纤维素及其衍生物是一大类可再生天然高分子材料,具有无毒、资源丰富以及种类繁多等特点,由它合成的纤维素基水凝胶具有良好的吸水保水性、生物相容性和生物可降解性等,可应用于医疗、环境、农业等多个领域。本文综述了近年来纤维素基水凝胶的构建及应用研究进展,将水凝胶的微观网络结构与宏观性能相结合,重点对比了单网络、互穿网络和半互穿网络纤维素基水凝胶的力学性能、溶胀性能和吸附性能等,并对其在医疗、环境、农业以及电子领域的应用进行总结。对开发兼具力学性能和生物相容性的纤维素基水凝胶以及未来发展更多绿色经济的方法合成纤维素基水凝胶材料并将之用于工业化提出了展望。

Stent-assisted coiling of intracranial carotid ophthalmic segment aneurysm segment aneurysms:Long-term follow-up from a single center

Background:To evaluate the efficacy of stent-assisted coiling(SAC)for the treatment of carotid ophthalmic segment aneurysm segment aneurysms(OSAs)of the internal carotid artery(ICA)through detailed long-term follow-up of a large patient cohort.Methods:We retrospectively analyzed 88 consecutive patients with OSAs between January 2009 and January 2020 at our center.Angiographic results were evaluated using the modified Raymond grading system and clinical outcomes were evaluated using the mRS scale.The primary endpoints were major aneurysm recurrence and poor clinical outcomes for at least 18 months of follow-up.The patients were asked to attend clinical follow-up assessments and possibly undergo DSA or MR via telephone.Results:We enrolled 88 patients with 99 OSAs treated with coiling,of whom 76 were treated with SAC.The coiling procedures were successful in all 88 patients.Overall,complications occurred in 8 patients(9.1%).No procedure-related mortality was observed.67(76.1%)experienced immediate aneurysm occlusion at the end of the procedure.Long-term angiographic follow-up(18 months)was available in 45/88 aneurysms(51%)(average 18.7±5.2 months).Four patients continued their follow-up for 5 years after initial aneurysm treatment.After a clinical follow-up time of 28.7 months(range,12-51 months),85 patients(95.5%)achieved favorable clinical outcomes(mRS scores of 0-2).Conclusions:This study indicates that SAC treatment is a safe and effective therapeutic alternative for ruptured and unruptured OSAs.The procedural risks are low with relatively long-term effectiveness.

Chemical looping catalytic gasification of biomass over active LaNixFe1-xO_(3)perovskites as functional oxygen carriers

Oxygen carriers(OCs)with perovskite structure are attracting increasing interests due to their redox tunability by introducing various dopants in the structure.In this study,LaNixFe1-xO3(x=0,0.1,0.3,0.5,0.7,1.0)perovskite OCs have been prepared by a citric acid–nitrate sol–gel method,characterized by means of X-ray diffraction(XRD)analysis and tested for algae chemical looping gasification in a fixed bed reactor.The effects of perovskite types,OC/biomass mass ratio(O/B),gasification temperature and water injection rate on the gasification performance were investigated.Lower Ni-doped(0≤x≤0.5)perovskites crystalized in the rhombohedra system which was isostructural with LaNiO3,while those with composition 0.5≤x≤1 crystalized in the orthorhombic system.Despite the high reactivity for LaNiO_(3),LaNi_(0.5)Fe_(0.5)O_(3)(LN5F5)was found to be more stable at a high temperature and give almost as good results as LaNiO_(3)in the formation of syngas.The relatively higher syngas yield of 0.833 m^(3)·kg^(-1) biomass was obtained under the O/B of 0.4,water injection rate of 0.3 ml·min^(-1) and gasification temperature at 850C.Continuous high yield of syngas was achieved during the first 5 redox cycles,while a slight decrease in the reactivity for LN5F5 after 5 cycles was observed due to the adhesion of small grains occurring on the surface of OCs.However,an obvious improvement in the gasification performance was attained for LN5F5 compared to raw biomass direct gasification,indicating that LN5F5 is a promising functional OC for chemical looping catalytic gasification of biomass.

Helicobacter pylori antibody responses in association with eradication outcome and recurrence： a population-based intervention trial with 7.3-year follow-up in China

Objective： To identify serum biomarkers that may predict the short or long term outcomes of anti-Helicobacter gylori （H. pylori） treatment, a follow-up study was performed based on an intervention trial in Linqu County, China. Methods： A total of 529 subjects were selected randomly from 1,803 participants to evaluate total anti-H, pylori immunoglobulin G （IgG） and 10 specific antibody levels before and after treatment at 1-, 2- and 7.3-year. The outcomes of anti-H, pylori treatment were also parallelly assessed by 13C-urea breath test at 45-d after treatment and 7.3-year at the end of follow-up. Results： We found the medians of anti-H, pylori IgG titers were consistently below cut-off value through 7.3 years in eradicated group, however, the medians declined in recurrence group to 1.2 at 1-year after treatment and slightly increased to 2.0 at 7.3-year. While the medians were significantly higher （〉3.0 at 2- and 7.3-year） among subjects who failed the eradication or received placebo. For specific antibody responses, baseline seropositivities of FliD and HpaA were reversely associated with eradication failure [for FIiD, odds ratio （OR）=0.44, 95% confidence interval （95% CI）： 0.27-0.73; for HpaA, OR=0.32, 95% Ch 0.I7-0.60]. The subjects with multiple positive specific antibodies at baseline were more likely to be successfully eradicated in a linear fashion （Ptrend=0.006）. Conclusions： Our study suggested that total anti-H, pylori IgG level may serve as a potential monitor of long- term impact on anti-H, pylori treatment, and priority for H. pylori treatment may be endowed to the subjects with multiple seropositive antibodies at baseline, especially for FliD and HapA.

An erratum on “Application of three-dimensional printing in interventional medicine” [J Interv Med(February 2020) 1–16]

After the publication of this work,1 the authors noticed and confirmed that the Funding Information was mistakenly omitted from the article.The statement“This study was supported by grants from the National Natural Science Foundation of China,grant no.81370041,81471760,81671655,the Outstanding Clinical Discipline Project of Shanghai Pudong,grant no.PWYgy2018-04.The authors declare that they have no conflicts of interest.”should be included in the Funding information section of the paper which is missing.We apologize for the error.

Performance of common buckwheat(Fagopyrum esculentum M.) supplied with selenite or selenate for selenium biofortification in northeastern China

Selenium(Se)deficiency commonly occurs in soils of northeastern China and leads to insufficient Se intake by humans.A two-year field study of Se biofortification of common buckwheat supplied with 40 g Se ha^(-1)as selenite(Se(IV)),selenate(Se(VI)),or a combination(1/2 Se(IV+VI))was performed to investigate Se accumulation and translocation in plants and determine the effects of different forms of Se on the grain yield,biomass production,and Se use efficiency of plants and seeds.Se application increased seed Se concentrations to 47.1–265.1μg kg^(-1).Seed Se concentrations following Se(VI)or 1/2 Se(IV+VI)treatment exceeded 100μg kg^(-1),an amount suitable for crop Se biofortification.Se concentration in shoots and roots decreased with plant development,and Se translocation from root to shoot in Se(IV)-treated plants was lower than that in plants treated with 1/2 Se(IV+VI)and Se(VI).Both grain yield and biomass production increased under 1/2 Se(IV+VI)treatment,with grain yields reaching 1663.8 and 1558.5 kg ha^(-1)in 2015 and 2016,respectively,reflecting increases of 11.0% and 10.3% over those without Se application.The Se use efficiency of seeds and plants under Se(VI)treatment was significantly higher than those under 1/2 Se(IV+VI)and Se(IV)treatments.Thus,application of selenate could result in higher Se accumulation in buckwheat seeds than application of the other Se sources,but the combined application of selenate and selenite might be an alternative approach for improving buckwheat grain yield by Se biofortification in northeastern China.

Application of three-dimensional printing in interventional medicine

Introduction In recent years,three-dimensional printing(3DP),an additive manufacturing process,has gained widespread clinical application,and 3DP has been considered as the third industrial revolution.1 In its early introduction in the 1980s,3DP served as a software-controlled technology that converted computer-aided-design(CAD)data into a physical object via a single process.By depositing multiple two-dimensional cross-sections one above the other,3DP can now be used to build arbitrarily complex geometries and patient-specific constructs using the patient’s imaging data.Till date,computed tomography has been the main imaging data source for 3DP owing to its excellent spatial resolution.Furthermore,current 3D printers have enabled bedside on-demand fabrication of medical products in hospitals.New materials including polymers,ceramics,biomaterials,and metals have been developed for such applications over the last few decades.Medical fields that employ 3DP technologies have also expanded,such as tissue engineering,regenerative medicine,pharmaceutics,and medical models and devices.2 The market for additive manufacturing is expected to surpass$20 billion in the global industry by the end of the 2020.3 Although the use of 3DP technology in interventional medicine is still relatively new,advancements are occurring within this discipline at a rapid rate.Different 3DP technologies,materials,and clinical applications relevant to the interventional field are discussed in this article.

Green and compatible industrial development in Western China

Western China has lagged a lot in terms of industrial structure and economic development,compared with the national average.And China announced its target of CO_2 emission reduction,i.e.by 2020,CO_2 emission per GDP will drop by40-45%compared with 2005.The target will be incorporated into China's long-term industrial planning.Against this background,this paper will make a comprehensive examination of the industrial development of Western China,aiming to discover a green and compatible way.First,we analyze the spatiotemporal evolution of regional industrial structure for the period 2000-2010.Second,we try to discover the industrial structure optimization path for Western China by employing the Vector Auto Regression model.Lastly,we try to provide some advice and suggestions for further industrial development in Western China.Our examination shows that further industrial development in Western China should pay full attention to resource conservation and recycling,and develop on a green and compatible path.

Acoustic Emission Recognition Based on a Two-Streams Convolutional Neural Network

The Convolutional Neural Network(CNN)is a widely used deep neural network.Compared with the shallow neural network,the CNN network has better performance and faster computing in some image recognition tasks.It can effectively avoid the problem that network training falls into local extremes.At present,CNN has been applied in many different fields,including fault diagnosis,and it has improved the level and efficiency of fault diagnosis.In this paper,a two-streams convolutional neural network(TCNN)model is proposed.Based on the short-time Fourier transform(STFT)spectral and Mel Frequency Cepstrum Coefficient(MFCC)input characteristics of two-streams acoustic emission(AE)signals,an AE signal processing and classification system is constructed and compared with the traditional recognition methods of AE signals and traditional CNN networks.The experimental results illustrate the effectiveness of the proposed model.Compared with single-stream convolutional neural network and a simple Long Short-Term Memory(LSTM)network,the performance of TCNN which combines spatial and temporal features is greatly improved,and the accuracy rate can reach 100%on the current database,which is 12%higher than that of single-stream neural network.

Effects of Helicobacter pylori eradication on the profiles of blood metabolites and their associations with the progression of gastric lesions: a prospective follow-up study

Objective:This study aimed at examining the alterations in metabolomic profiles caused by treatment of H.pylori infection,and the associations between key plasma metabolites and the risk of gastric lesion progression during follow-up after treatment.Methods:An intervention trial was performed in 183 participants,117 of whom were H.pylori positive participants receiving treatment for H.pylori infection.H.pylori positive participants were prospectively followed for 182 to 1,289 days.Untargeted metabolomics assays were conducted on plasma samples collected at baseline,6 months after treatment,and during continued follow-up.Results:We identified 59 metabolites with differential posttreatment changes between participants with successful and failed H.pylori eradication,17 metabolites significantly distinguished participants with successful vs.failed eradication.Two metabolites[PC(18:1(11Z)/14:1(9Z))and(2S)-6-amino-2-formamidohexanamide]showed posttreatment changes positively associated with successful H.pylori eradication,and were inversely associated with the risk of gastric lesion progression among participants with successful eradication.In contrast,9-decenoic acid showed posttreatment changes inversely associated with successful eradication:its level was positively associated with the risk of gastric lesion progression among participants with successful eradication.Although the identified metabolites showed a temporary but significant decline after treatment,the trend generally reversed during continued follow-up,and pretreatment levels were restored.Conclusions:Treatment of H.pylori infection significantly altered plasma metabolic profiles in the short term,and key metabolites were capable of distinguishing participants with successful vs.failed eradication,but might not substantially affect metabolic regulation in the long term.Several plasma metabolites were differentially associated with the risk of gastric lesion progression among participants with successful or failed eradication.

In silico Cloning and Bioinformatics Analysis of OsARAB-1 Gene from Rice

[ Objective] This study aimed to perform in silico cloning and bioinformatics analysis of OsARAB-1 gene from rice. [Method] Using NP 174188.1 as a query probe, the full-length cDNA sequence of OsARAB-1 gene was obtained by in silico cloning. The nucleotide sequence and protein sequence were analyzed by bioinformatics software. [Result] The full-length cDNA of OsARAB-1 gene was obtained. The coding sequence （CDS） of OsARAB-1 gene is 1 086 bp in length, encoding a protein of 361 amino acid residues. OsARAB-1 gene was located in the genome sequence NC 008398.2 （6 769 813 -6 773 213 bp segment） of rice chro- mosome 5 by in silico mapping. OsARAB-1 protein is an extracellular hydrophilic protein, which is relatively stable, slightly alkaline. The secondary structure of OsARAB-1 protein is mainly composed of or-helices and random coils. OsARAB-1 protein has two functional domains ： SGNH hydrolase-type esterase and GDSL li- pase. There are 21 phosphorylation sites and seven O-[3-GlcNAc glycosylation sites. The putative active-site amino acid residues are Ser34, Glyl07, Asn167, Asp333 and His336, respectively. OsARAB-1 protein has the closest genetic relationship with esterase subtype B4FM12 from maize. The expression of OsARAB-1 gene plays an important role in the development and morphogenesis of rice and is related with rice blast resistance. [ Conclusion] This study laid a solid foundation for cloning and functional identification of OsARAB-1 gene with experimental methods.

那王府往事

清朝定鼎中原后皇族宗室多居住于京城,其中重要成员被册封为王爵,其府邸被称为王府,星罗棋布的王府是北京建筑与文化特色的重要组成部分。一般来说,清代蒙古王公的府第在其游牧领地,京城只是其驻京的寓所。但乾隆朝以来,因清朝下嫁公主而令蒙古额驸在京居住并由后嗣承继,原来赏赐的公主府逐渐演变为蒙古王府。那王府即是北京现保存较好的蒙古王府之一,原主乃是清朝外藩蒙古喀尔喀赛音诺颜部扎萨克亲王那彦图,其修建过程与历代拥有者的经历都蕴含了丰富的历史信息,让我们来一探究竟。

Architecture Design of an Integrated Communication and Broadcasting Network

Due to the power limitation of nodes in wire-less sensor networks (WSNs), how to maximize network lifetime has become a critical issue for deployment of WSNs. Although several schemes have been proposed for 2D WSNs, few for 3D WSNs are known. In this paper, we present a scheme to maximize network lifetime for 3D WSNs through balancing energy consumption, as an extension of the existing scheme for 2D WSNs proposed recently [1]. Same as [1], we formulate the energy consumption balancing problem as an problem of optimal distribution of transmitting data by combining the techniques of sphere-corona based network division, mixed-routing and data aggregation. We first present a Tiled-block based routing scheme in order to balance energy consumption among nodes in each sphere-corona. Then we design an algorithm to compute the optimal distribution ratio of transmitting data between direct and hop-by-hop transmission, with the purpose of balancing energy consumption among nodes across different sphere-coronas. We show maximizing network lifetime through computing the optimal number of sphere-coronas. Afterwards a energy consumption balanced data collecting protocol (ECBDC) is designed and a solution to extend ECBDC to largescale WSNs is also presented. Simulaiton results show that ECBDC is superior to conventional direct and multihop transmission schemes in network lifetime.

Application of Social Support System in the Rehabilitation of Vagrants and Beggars with Mental Illness

Objective:Analyze the specific role of social support in vagrants and beggars with mental illness.Methods:80 patients with vagrant psychosis admitted into our hospital from April 2020 to April 2021 were randomly selected.The patients were treated for more than 6 months.The patients were randomly divided into two groups by drawing lots,with 40 cases in each group.The control group received routine nursing,and the observation group received routine nursing along with social support.The objective support,subjective support,and the utilization of support,which were combined into total social support of the two groups were compared after different nursing interventions.Results:After different nursing interventions,through the comparison of social support scale,the scores of objective support,subjective support,and utilization of support,and the total social support in the observation group were higher than the control group,and the differences were statistically significant(P<0.05).Conclusion:The application of social support system and while providing routine nursing among vagrants and beggars with psychosis can effectively improve their mental status,make them feel more valued and supported,and help improve their mental health and quality of life.

梨状窝后壁鱼刺致急性颈段硬脊膜外感染1例

下咽异物是耳鼻喉科常见疾病,由于该区域的解剖结构比较隐蔽,可能存在因咽腔狭窄暴露不佳而漏诊的情况。因异物留存时间过长导致的各类并发症临床文献时有报道,由于下咽梨状窝区域异物造成的急性颈段硬脊膜外感染病例临床上罕有报道。本例患者异物取出后1周出现了对侧的颈部疼痛、活动时加重,早期症状不典型,病情进展后出现颈部疼痛及感染症状持续加重,颈部增强CT及MRI检查明确了感染的部位及罕见病因,经过积极的抗感染治疗,患者痊愈。1个月后随访,患者状态良好。

表面活性剂驱油机理研究新进展:胶束增溶和原位乳化

降低油/水界面张力被认为是表面活性剂提高原油采收率的主要机理,但部分现场试验表明,低浓度表面活性剂驱在未达到超低界面张力的情况下也可以提高采收率,多孔介质中表面活性剂溶液与原油逐步接触后的演化过程尚无研究.针对这些问题,我们从微米和纳米尺度上深入剖析了表面活性剂驱油机理,提出了“胶束增溶,乳化携油”的新认识.通过吸光度测试、小角度中子散射和透射电子显微镜等方法评价了表面活性剂溶液与油的相互作用,发现表面活性剂胶束可通过增溶部分原油的方式提高采收率;利用微流控技术研究了表面活性剂驱油过程中的乳化过程,发现原位乳化主要通过封堵大孔道和乳化携油提高采收率.相关研究结果有助于深入理解表面活性剂溶液与原油间的相互作用,为生产实践中的配方优化提供理论依据.

A simple fluorescent sensor for highly sensitive detection of UO_(2)2+

Extensive application of nuclear energy has caused widespread environmental uranium contamination.New detection approaches without complicated sample pretreatment and precision instruments are in demand for on-site and in-time determination of uranyl ions in environmental monitoring, especially in an emergency situation. In this work, a simple and effective fluorescent sensor(Z)-N’-hydroxy-4-(1,2,2-triphenylvinyl)benzimidamide(TPE-A) with aggregation-induced emission(AIE) character was established and studied. It could realize to detect UO_(2)2+via quenching the fluorescence of its aggregation-induced emission, with good selectivity and sensitivity. Such strategy shows a wide linear range from 5.0 × 10^(-8)mol/L to 4.5 × 10^(-7)mol/L(R^(2)= 0.9988) with exceptional sensitivity reaching 4.7 × 10^(-9)mol/L, which is far below the limit for uranium in drinking water(30 μg/L, ca. 1.1 × 10-7mol/L) stipulated by the WHO.A response time less than four minutes make it rapid for uranyl ion measurement. It was applied for detection of uranyl ion in spiked river water samples with recoveries in the range of 98.7%-104.0%, comparable to those obtained by ICP-MS. With the advantages of portable apparatus, rapid detection process and high sensitivity, TPE-A can serve as a promising fluorescent sensor for the detection of UO_(2)2+in environmental water samples.