Congestion Relief in Downlink OFDMA Cellular System Using Inter-Cell Relay

This paper proposes the concept of inter-cell relay for downlink orthogonal frequency division multiple access(OFDMA) cellular systems, which uses multi-hop to relay calls from overloaded cells to light-load neighboring cells. It is shown that when using inter-cell relay, the number of calls in the congestion cell can be significantly increased. The congestion cell is divided into two parts. One is called non-relay area(NRA), in which a call directly communicates with the base station(BS) of a congested cell. The other is called relay area(RA), in which a call communicates with the BS of a neighboring cell through a relay station(RS). The two parts have different user-call densities. By adjusting the densities of two parts, we will maximize the number of supported calls inside a congested cell. The results show the benefits gained from inter-cell relay in congestion relief, which can reduce cell congestion by fully utilizing the available resources in the neighboring cells.

Effects of COL1A1 and SYTL2 on inflammatory cell infiltration and poor extracellular matrix remodeling of the vascular wall in thoracic aortic aneurysm

Background:Thoracic aortic aneurysm(TAA)is a fatal cardiovascular disease,the pathogenesis of which has not yet been clarified.This study aimed to identify and validate the diagnostic markers of TAA to provide a strong theoretical basis for developing new methods to prevent and treat this disease.Methods:Gene expression profiles of the GSE9106,GSE26155,and GSE155468 datasets were acquired from the Gene Expression Omnibus(GEO)database.Differentially expressed genes(DEGs)were identified using the"limma"package in R.Least absolute shrinkage and selection operator(LASSO),support vector machine-recursive feature elimination(SVM-RFE),random forest,and binary logistic regression analyses were used to screen the diagnostic marker genes.Single-sample gene set enrichment analysis(ssGSEA)was used to estimate immune cell infiltration in TAA.Results:A total of 16 DEGs were identified.The enrichment and functional correlation analyses showed that DEGs were mainly associated with inflammatory response pathways and collagen-related diseases.Collagen type I alpha 1 chain(COL1A1)and synaptotagmin like 2(SYTL2)were identified as diagnostic marker genes with a high diagnostic value for TAA.The expression of COL1A1 and SYTL2 was considerably higher in TAA vascular wall tissues than in the corresponding normal tissues,and there were significant differences in the infiltration of immune cells between TAA and normal vascular wall tissues.Additionally,COL1A1 and SYTL2 expression were associated with the infiltration of immune cells in the vascular wall tissue.Single-cell analysis showed that COL1A1 in TAA was mainly derived from fibroblasts and SYTL2 mainly from cluster of differentiation(CD)8+T cells.In addition,single-cell analysis indicated that fibroblasts and CD8+T cells in TAA were significantly higher than those in normal arterial wall tissue.Conclusions:COL1A1 and SYTL2 may serve as diagnostic marker genes for TAA.The upregulation of SYTL2 and COL1A1 may be involved in the inflammatory infiltration of the vessel wall and poor extracellular matrix remodeling,promoting the progression of TAA.

8F Zelante和6F Solent血栓去除导管治疗下肢深静脉血栓形成的疗效对比分析

目的比较8F Zelante和6F Solent血栓去除导管治疗下肢深静脉血栓形成(DVT)的疗效。方法回顾性分析复旦大学附属中山医院厦门医院血管外科2020年6月至2022年12月收治的51例急性或亚急性DVT患者的临床资料, 其中男性22例, 年龄(60.5±14.4)岁。根据血栓去除导管不同, 分为Zelante组和Solent组。比较分析两组的溶栓时间、支架植入率、血栓清除率、通畅率、深静脉血栓后综合征(PTS)发生率和并发症等指标。结果 51例DVT患者中, Zelante组15例, Solent组36例。Zelante组术中吸栓时间[(322.7±78.1)s 比(416.4±61.5)s, t=4.577, P=0.001]和溶栓时间[(46.3±28.8)h 比(96.1±39.5)h, t=2.796, P=0.010]少于Solent组, 但总体血栓清除效果优于Solent组(χ2=7.913, P=0.019), 差异均具有统计学意义。两组支架植入率、单次住院滤器回收情况比较, 差异无统计学意义(P均>0.05)。51例患者均获得随访, 随访时间为(12.6±7.1)个月(范围:1~30个月)。随访期间, Zelante组无PTS出现。Solent组中再干预3例;PTS 6例, 其中3例为重度。结论相较6F Solent血栓去除导管, 8F Zelante导管治疗DVT具有更好的血栓清除效果, 并发症更少。