Polysaccharide extract from Rosa laevigata fruit attenuates inflammatory obesity by targeting redox balance and gut interface in high-fat diet-fed rats

Low-molecular-weight polysaccharides(RLPs)extracted from Rosa laevigata fruits showed multiple biofunctions in Asia.This study aimed to investigate its anti-inflammatory obesity effect in high-fat dietfed rats and further elucidated the underlying molecular mechanism by multi-omics methods.The results showed that RLPs administration had significantly restored immune organ indexes and reduced body weight gain.RNA-seq revealed that the effect of RLPs was partially attributed to its regulation on PPARs signaling by increasing the expressions of Scd,Acox3 and Hmgcs2,and on other redox-related pathways by decreasing the expressions of Cyp2 e1,Il1-r1 and Lbp.Moreover,16 S rRNA sequencing coupled with metagenome sequencing showed that RLPs had significantly reduced the ratio of Firmicutes/Bacteroidetes from 8.01 to2.37,and significantly increased the relative abundances of Alistipes,Prevotella,and Akkermansia from 0.36%,1.10%and 2.61%to 0.65%,2.37%and 4.42%,respectively.Spearman correlation analysis result indicated that the abundances of Lachnospiraceae,Prevotella and Bacteroidales were significantly negatively correlated with obesity phenotype,liver function and inflammatory factors.These results revealed that RLPs exerted significant anti-inflammatory obesity property partially via regulation on gut microbiota interface and the redox balance.Therefore,RLPs could be a promising functional food resource with the potential for redox imb alance-related diseases chemoprevention.

A new synthetic chelating collector for the flotation of oxidized-lead mineral

A new synthetic reagent DPTUHP [diphenyl α-（3-phenylthioureido） hexylpbosphonate] containing a hydrocarbon chain nonpolar group, a thioureido, and a phosphonate easter chelating group, has proven to be an effective collector for the flotation of cerussite mineral. The synthetic method utilized the Mannich-type reaction of an N-monosubstituted thiourea, an aldehyde, and triphenyl phosphate in glacial acetic acid solution. The experimental results of flotation of the cerussite mineral show that the collector has stronger collecting ability and higher selectivity in a neutral and a slightly alkaline medium, especially in the pulp of pH=8. Using the measurements by infrared spectroscopy （IR） and X-ray photoelectron spectroscopy （XPS） of the cerussite mineral, the collector, as well as the cerussite treated with the collector, the flotation mechanism of cerussite has been discussed. It is concluded that the adsorption of collector on cerussite is a chemical adsorption through the electron donor atoms of the collector chelating the Pb （ Ⅱ ） of cerussite to form chelate.

Experimental and Numerical Studies of the Wave-Induced Responses of a River-to-Sea Ship

The ship motions and wave-induced loads of a new type of river-to-sea ship are investigated experimentally and numerically. A river-to-sea ship is an unconventional type of container ship characterized by high breadth to draft ratio and low length to breadth ratio, which makes it more prone to hydroelasticity than conventional ships of the same size. A segmented model was tested under two loading conditions, namely, ballast and loaded conditions, to determine the vertical motions and wave-induced loads under each condition. Results are compared with numerical simulations in the frequency domain. The wave-induced responses are calculated by a nonlinear time domain code at each time step. The response amplitude operators of vertical ship responses in regular waves are analyzed, and the wave-induced responses are consistent with the experimental results.

铝合金板以及加筋板极限受压强度研究

This work reviews the ultimate compressive strength of aluminium plates and stiffened panels.The effect of boundary condition,initial imperfection,welding-induced residual stress and heat-affected zone are discussed.As the effect of manufacturing technology lacks in the literature,this effect is analysed employing the finite element method,considering the technology of welding and integrated extrusion.The numerical analyses have shown that the ultimate strength of the integrated extruded stiffened panel is relatively higher than the one of the traditional welded panel.

Research progress on the origin traceability of edible oils

The origin traceability of edible oil is an effective way to protect the legitimate rights and interests of producers and consumers.This review briefly summarizes research progress on origin traceability technologies for edible oils including stable isotope ratio mass spectrometry,mineral element fingerprint analysis,organic component fingerprint analysis,near-infrared spectroscopy,nuclear magnetic resonance technology and biochemical analysis.Moreover,the development trends in edible oil origin traceability technology were proposed.

Structural and acoustic response of a finite stiffened conical shell

In this paper, a precise transfer matrix method is presented to calculate the struc- tural and acoustic responses of the conical shell. The governing equations of conical shells are written as a coupled set of first order differential equations. The field transfer matrix of the shell and non-homogenous term resulting from the external excitation are obtained by precise integra- tion method. After assembling the field transfer matrixes, the whole matrix describing dynamic behavior of the stiffened conical shell is obtained. Then the structural and acoustic responses of the shell are solved by obtaining unknown sound pressure coefficients. The natural frequencies of the shell are compared with the FEM results to test the validity. Furthermore, the effects of the semi-vertex angle, driving force directions and boundary conditions on the structural and acoustic responses are studied.

A High-Order Numerical Method to Study Three-Dimensional Hydrodynamics in a Natural River

A high-order numerical method for three-dimensional hydrodynamics is p-resented.The present method applies high-order compact schemes in space and a Runge-Kutta scheme in time to solve the Reynolds-averaged Navier-Stokes equations with the k-ǫturbulence model in an orthogonal curvilinear coordinate system.In ad-dition,a two-dimensional equation is derived from the depth-averaged momentum equations to predict the water level.The proposed method isfirst validated by its application to simulateflow in a 180◦curved laboratoryflume.It is found that the simulated results agree with measurements and are better than those from SIMPLEC algorithm.Then the method is applied to study three-dimensional hydrodynamics in a natural river,and the simulated results are in accordance with measurements.