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Effects of leukemia inhibitory factor and basic fibroblast growth factor on free radicals and endogenous stem cell proliferation in a mouse model of cerebral infarction 被引量:2
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作者 weihui huang Yadan Li +2 位作者 Yufeng Lin Xue Ye Dawei Zang 《Neural Regeneration Research》 SCIE CAS CSCD 2012年第19期1469-1474,共6页
The present study established a mouse model of cerebral infarction by middle cerebral artery occlusion,and monitored the effect of 25 μg/kg leukemia inhibitory factor and(or) basic fibroblast growth factor administra... The present study established a mouse model of cerebral infarction by middle cerebral artery occlusion,and monitored the effect of 25 μg/kg leukemia inhibitory factor and(or) basic fibroblast growth factor administration 2 hours after model establishment.Results showed that following administration,the number of endogenous neural stem cells in the infarct area significantly increased,malondialdehyde content in brain tissue homogenates significantly decreased,nitric oxide content,glutathione peroxidase and superoxide dismutase activity significantly elevated,and mouse motor function significantly improved as confirmed by the rotarod and bar grab tests.In particular,the effect of leukemia inhibitory factor in combination with basic fibroblast growth factor was the most significant.Results indicate that leukemia inhibitory factor and basic fibroblast growth factor can improve the microenvironment after cerebral infarction by altering free radical levels,improving the quantity of endogenous neural stem cells,and promoting neurological function of mice with cerebral infarction. 展开更多
关键词 碱性成纤维细胞生长因子 白血病抑制因子 小鼠模型 脑梗塞 内源性 自由基 因子和 细胞增殖
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Fabrication of CdS/SnS Heterojunction for Photovoltaic Application
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作者 Hongnan Li Shuying Cheng +3 位作者 Jie Zhang weihui huang Haifang Zhou Hongjie Jia 《World Journal of Condensed Matter Physics》 2015年第1期10-17,共8页
SnS/CdS heterojunction is a promising system for photovoltaic application. SnS thin films were thermally evaporated onto CdS/ITO coated glass substrates. The structure of the device was glass/ ITO/CdS/SnS/In/Ag and I-... SnS/CdS heterojunction is a promising system for photovoltaic application. SnS thin films were thermally evaporated onto CdS/ITO coated glass substrates. The structure of the device was glass/ ITO/CdS/SnS/In/Ag and I-V curves of the fabricated devices were measured under dark and illuminated conditions, respectively. We discussed the relationship of the thickness and annealing temperature of CdS buffer layers with the performance of SnS/CdS heterojunctions. The optimum thickness and annealing temperature of the CdS buffer layers were 50 nm and 350°C, respectively. The best device had a conversion efficiency of 0.0025%. 展开更多
关键词 SNS Films HETEROJUNCTION Thermally Vacuum-Evaporation I-V CURVES
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