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Tailoring spatiotemporal dynamics of plasmonic vortices
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作者 Xinyao Yuan Quan Xu +7 位作者 Yuanhao Lang Xiaohan Jiang Yuehong Xu Xieyu Chen Jie Han Xueqian zhang Jiaguang Han weili zhang 《Opto-Electronic Advances》 SCIE EI CAS CSCD 2023年第4期16-26,共11页
Plasmonic vortices confining orbital angular momentums to surface have aroused wide research interest in the last decade.Recent advances of near-field microscopes have enabled the study on the spatiotemporal dynamics ... Plasmonic vortices confining orbital angular momentums to surface have aroused wide research interest in the last decade.Recent advances of near-field microscopes have enabled the study on the spatiotemporal dynamics of plasmonic vortices,providing a better understanding of optical orbital angular momentums in the evanescent wave regime.However,these works only focused on the objective characterization of plasmonic vortex and have not achieved subjectively tailoring of its spatiotemporal dynamics for specific applications.Herein,it is demonstrated that the plasmonic vortices with the same topological charge can be endowed with distinct spatiotemporal dynamics by simply changing the coupler design.Based on a near-field scanning terahertz microscopy,the surface plasmon fields are directly obtained with ultrahigh spatiotemporal resolution,experimentally exhibiting the generation and evolution divergences during the whole lifetime of plasmonic vortices.The proposed strategy is straightforward and universal,which can be readily applied into visible or infrared frequencies,facilitating the development of plasmonic vortex related researches and applications. 展开更多
关键词 plasmonic vortex surface plasmon spatiotemporal dynamics optical orbital angular momentum
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Regulating the growth of lithium dendrite by coating an ultra-thin layer of gold on separator for improving the fast-charging ability of graphite anode 被引量:2
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作者 Shuaishuai Yan Xiaoxia Chen +5 位作者 Pan Zhou Peican Wang Hangyu Zhou weili zhang Yingchun Xia Kai Liu 《Journal of Energy Chemistry》 SCIE EI CAS CSCD 2022年第4期467-473,共7页
With the ever-growing application of lithium-ion batteries(LIBs), their fast-charging technology has attracted great interests of scientists. However, growth of lithium dendrites during fast charge of the bat teries w... With the ever-growing application of lithium-ion batteries(LIBs), their fast-charging technology has attracted great interests of scientists. However, growth of lithium dendrites during fast charge of the bat teries with high energy density may pose great threats to the operation and cause serious safety issues Herein, we prepared a functional separator with an ultra-thin(20 nm) layer of Au nanoparticles deposited by evaporation coating method which could regulate growth direction and morphology of the lithium dendrites, owing to nearly zero overpotential of lithium meal nucleation on lithiated Au. Once the Li den drites are about to form on the graphite anode during fast charging(or lithiation), they plate predomi nantly on the Au deposited separator rather than on the graphite. Such selective deposition does no compromise the electrochemical performance of batteries under normal cycling. More importantly, i enables the better cycling stability of batteries at fast charge condition. The Li/Graphite cells with Au nanoparticles coated separator could cycle stably with a high areal capacity retention of 90.5% over 95 cycles at the current density of 0.72 m A cm^(-2). The functional separator provides an effective strategy to adjust lithium plating position at fast charge to ensure high safety of batteries without a compromise on the energy density of LIBs. 展开更多
关键词 Fast-charging Functional separator Lithium-ion batteries DENDRITES Safety
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Anti-Attacking Modeling and Analysis of Cyberspace Mimic DNS 被引量:1
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作者 Lei He Quan Ren +2 位作者 Bolin Ma weili zhang Jiangxing Wu 《China Communications》 SCIE CSCD 2022年第5期218-230,共13页
With the rapid development of information technology,the cyberspace security problem is increasingly serious.Kinds of dynamic defense technology have emerged such as moving target defense and mimic defense.This paper ... With the rapid development of information technology,the cyberspace security problem is increasingly serious.Kinds of dynamic defense technology have emerged such as moving target defense and mimic defense.This paper aims to describe the architecture and analyze the performance of Cyberspace Mimic DNS based on generalized stochastic Petri net.We propose a general method of anti-attacking analysis.For general attack and special attack model,the available probability,escaped probability and nonspecial awareness probability are adopted to quantitatively analyze the system performance.And we expand the GSPN model to adjust to engineering practice by specifying randomness of different output vectors.The result shows that the proposed method is effective,and Mimic system has high anti-attacking performance.To deal with the special attack,we can integrate the traditional defense mechanism in engineering practice.Besides,we analyze the performance of mimic DNSframework based on multi-ruling proxy and input-output desperation,the results represent we can use multi ruling or high-speed cache servers to achieve the consistent cost of delay,throughput compared with single authorized DNS,it can effectively solve 10%to 20%performance loss caused by general ruling proxy. 展开更多
关键词 cyberspace mimic DNS generalized stochastic Petri net anti-attacking MODELING performance
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Active-Thermal-Tunable Terahertz Absorber with Temperature-Sensitive Material Thin Film 被引量:1
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作者 Zhao zhang Zhen Tian +6 位作者 Chao Chang Xueguang Wang Xueqian zhang Chunmei Ouyang Jianqiang Gu Jiaguang Han weili zhang 《Nanotechnology and Precision Engineering》 EI CAS CSCD 2018年第2期123-128,共6页
It is shown that active-tunable terahertz absorbers can be realized in a sandwich-structured system comprising an ultrathin dielectric film(polyimide) on a temperature-sensitive substrate(InSb) with a metal film on th... It is shown that active-tunable terahertz absorbers can be realized in a sandwich-structured system comprising an ultrathin dielectric film(polyimide) on a temperature-sensitive substrate(InSb) with a metal film on the back by utilizing the intrinsic carrier density(N) variation in InSb. When increasing the temperature from 250 to 320 K, N in InSb varied from ~5.50×1015 to ~2.98×1016 cm–3. Fixing the thickness of dielectric film with the value of 1.37 μm, the absorption peak shifted from 1.41 to 3.29 THz while keeping absorption higher than 99%. This active tunability can respond to even a slight temperature perturbation, and shows polarization insensitivity as well as high tolerance of incidence-angle(absorption peak can still exceed 90% even the incidence angle reaches 60°). Besides, the refractive index of polyimide(PI) has thermal stability at the terahertz range and the merit of good workability. These characteristics guarantee the stability of activetunable performance. The peculiarities and innovations of this proposal promise a wide range of high efficiency terahertz devices, such as thermal sensors, spatial light modulators(SLMs) and so on. 展开更多
关键词 Terahertz wave ABSORBER Thin film INSB
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Decoherence of fiber light sources using a single-trench fiber 被引量:1
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作者 张华辉 张伟利 +5 位作者 王昭 朱洪杨 余超 郭佳宇 王珊珊 饶云江 《Chinese Physics B》 SCIE EI CAS CSCD 2020年第12期281-285,共5页
Decoherence of fiber laser sources is of great importance in imaging applications,and most current studies use ordinary multi-mode fibers(MMFs).Here,a newly designed single-trench fiber(STF)is investigated to reduce t... Decoherence of fiber laser sources is of great importance in imaging applications,and most current studies use ordinary multi-mode fibers(MMFs).Here,a newly designed single-trench fiber(STF)is investigated to reduce the spatial coherence of fiber light source and compared with MMFs.By bending two fibers with different turns,speckle contrast of a 0.8-m-long STF can be reduced from 0.13 to 0.08,while a 0.8-m-long MMF shows an inverse result.Through speckle contrast and decoupling-mode analysis,the reason of this inverse trend is revealed.Firstly,the STF supports more modes than the MMF due to its larger core diameter.Secondly,mode leak from the first core of the STF can couple to the second core when bending the STF.Thus,power distribution among high and low-order modes become more even,reducing the spatial coherence considerably.However,in the MMF,high-order modes become leaky modes and decrease slightly when bending the fiber.This work provides a new method to modulate coherence of light source and a new angle to study decoherence principle using special fibers. 展开更多
关键词 single-trench fiber multi-mode fiber bending fiber speckle contrast
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Path Exploration and Countermeasure Innovation for Developing Circular Agriculture in Southeast China 被引量:1
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作者 Boqi WENG weili zhang Yixiang WANG 《Asian Agricultural Research》 2014年第3期20-25,30,共7页
This paper firstly elaborated current situation of agricultural resources and ecological environment protection of China,and pointed out that circular agriculture is an inevitable choice for sustainable development of... This paper firstly elaborated current situation of agricultural resources and ecological environment protection of China,and pointed out that circular agriculture is an inevitable choice for sustainable development of agriculture and effective approach for low-carbon economic development. Then,it analyzed mode and benefit of typical circular agriculture,such as ecological orchard in southeast hills,sightseeing ecological agricultural garden,and crop straw use. Finally,it came up with countermeasures for further developing circular agriculture,including integrating building system and establishing suitable mode,formulating production standard and ensuring food safety,strengthening technological innovation,and supporting sustainable development. 展开更多
关键词 SOUTHEAST Circular AGRICULTURE RESOURCE use Techni
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Trial of Intensive Blood-Pressure Control in Older Patients with Hypertension 被引量:1
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作者 weili zhang 《四川生理科学杂志》 2021年第8期1472-1472,共1页
Results:Of the 9624 patients screened for eligibility,8511 were enrolled in the trial;4243 were randomly assigned to the intensive-treatment group and 4268 to the standard-treatment group.At 1 year of follow-up,the me... Results:Of the 9624 patients screened for eligibility,8511 were enrolled in the trial;4243 were randomly assigned to the intensive-treatment group and 4268 to the standard-treatment group.At 1 year of follow-up,the mean systolic blood pressure was 127.5 mm Hg in the intensive-treatment group and 135.3 mm Hg in the standard-treatment group.During a median follow-up period of 3.34 years,primary-outcome events occurred in 147 patients(3.5%)in the intensive-treatment group,as compared with 196 patients(4.6%)in the standard-treatment group(hazard ratio,0.74;95%confidence interval[CI],0.60 to 0.92;P=0.007).The results for most of the individual components of the primary outcome also favored intensive treatment:the hazard ratio for stroke was 0.67(95%CI,0.47 to 0.97),acute coronary syndrome 0.67(95%CI,0.47 to 0.94). 展开更多
关键词 BLOOD PATIENTS ACUTE
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The associations between telomere trajectory and blood pressure change in a longitudinal hypertensive cohort in China
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作者 Shuyuan zhang Yu Chen +5 位作者 Shujun Yang Rongxia Li Li Fu Dianwen Wang Rutai Hui weili zhang 《中国循环杂志》 CSCD 北大核心 2018年第S01期162-162,共1页
Objective Telomere length, as an emerging marker of biological age,isrelatedwithhypertension.Ouraimistoinvestigatethe relationship between telomere trajectory and blood pressure change as well as the incident cardiova... Objective Telomere length, as an emerging marker of biological age,isrelatedwithhypertension.Ouraimistoinvestigatethe relationship between telomere trajectory and blood pressure change as well as the incident cardiovascular events in a longitudinal hypertensive cohort in China. 展开更多
关键词 TELOMERE TRAJECTORY BLOOD PRESSURE a longitudinal HYPERTENSIVE COHORT
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Long-term stimulation of angiotensin Ⅱ induced endothelial senescence and dysfunction
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作者 Rongxia Li Shujun Yang +4 位作者 Xue Mi Yunyun Yang RutaiHui Yu Chen weili zhang 《中国循环杂志》 CSCD 北大核心 2018年第S01期129-129,共1页
Objective Vascular endothelial cells senescence is one of major risk factors for atherosclerotic diseases,which can be induced by endogenous peptides,such as angiotensin Ⅱ(Ang Ⅱ).However,the effect of chronic Ang Ⅱ... Objective Vascular endothelial cells senescence is one of major risk factors for atherosclerotic diseases,which can be induced by endogenous peptides,such as angiotensin Ⅱ(Ang Ⅱ).However,the effect of chronic Ang Ⅱ stimulation on endothelial senescence remains unknown.Therefore,this study aims to investigate the changes in morphology and function of human umbilical vein endothelial cells(HUVECs)in response to the chronic stimulation of Ang Ⅱ. 展开更多
关键词 ATHEROSCLEROTIC diseases angiotensinⅡ(AngⅡ) human UMBILICAL vein ENDOTHELIAL cells(HUVECs)
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Exciton-polariton based WS_(2)polarization modulator controlled by optical Stark beam
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作者 Mahnoor Shahzadi Chuyuan Zheng +2 位作者 Sheraz Ahmad Shanshan Wang weili zhang 《Opto-Electronic Advances》 SCIE EI CAS 2022年第11期54-60,共7页
The recent era of fast optical manipulation and optical devices owe a lot to exciton-polaritons being lighter in mass,faster in speed and stronger in nonlinearity due to hybrid light-matter characteristics.The room te... The recent era of fast optical manipulation and optical devices owe a lot to exciton-polaritons being lighter in mass,faster in speed and stronger in nonlinearity due to hybrid light-matter characteristics.The room temperature existence of polaritons in two dimensional materials opens up new avenues to the design and analysis of all optical devices and has gained the researchers attention.Here,spin-selective optical Stark effect is introduced to form a waveguide effect in uniform community of polaritons,and is used to realize polarization modulation of polaritons.The proposed device basically takes advantage of the spin-sensitive properties of optical Stark effect of polaritons inside the WS_(2)microcavity so as to guide different modes and modulate polarization of polaritons.It is shown that polaritonic wavepacket of different mode profiles can be generated by changing intensity of the optical Stark beam and the polarization of polaritons can be controlled and changed periodically along the formed waveguide by introduction birefringence that is sensitive to polarization degree of the optical Stark beam. 展开更多
关键词 Stark beam POLARITONS MODULATOR TMDs polarization degree
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Development Trend Analysis of Computer Management Information System
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作者 weili zhang Changsheng zhang +1 位作者 Chenghao Han Hongquan Li 《Journal of Electronic Research and Application》 2020年第1期7-13,共7页
Based on the retrospect and analysis of the main points of the development of computer management information system,on the basis of the study of relevant data such as enterprise units,mass media,personal information ... Based on the retrospect and analysis of the main points of the development of computer management information system,on the basis of the study of relevant data such as enterprise units,mass media,personal information and information security,and according to the actual situation of our country,this paper intentionally and systematically collects relevant research materials on the role of management information system in the survival and development of enterprises,and aims at one or more merits.To study its impact,this paper focuses on three aspects:application analysis,development direction and implementation strategy,which can provide strong reference and guidance for the application of enterprise computer management system. 展开更多
关键词 MANAGEMENT information system DEVELOPMENT TREND REALIZATION STRATEGY
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Research on the Development and Application of Campus Card in Colleges and Universities
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作者 Wei zhang Xiushuang Yi +1 位作者 Chenghao Han weili zhang 《Journal of Contemporary Educational Research》 2020年第4期65-73,共9页
With the rapid development of the construction of smart campus in Colleges and universities and the maturity of related technologies,campus card has become the most frequently used and the most frequently used core co... With the rapid development of the construction of smart campus in Colleges and universities and the maturity of related technologies,campus card has become the most frequently used and the most frequently used core component of smart campus.Based on the actual construction of onecard system in domestic universities and the author’s years of experience in campus card management,this paper makes a systematic study on the development of campus card,virtual campus card,big data application,information security and other aspects,with a view to providing effective reference for the construction of campus card in Colleges and universities. 展开更多
关键词 Campus card Virtual card Big data application
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Active terahertz beam steering based on mechanical deformation of liquid crystal elastomer metasurface 被引量:4
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作者 Xiaolin Zhuang Wei zhang +7 位作者 Kemeng Wang Yangfan Gu Youwen An Xueqian zhang Jianqiang Gu Dan Luo Jiaguang Han weili zhang 《Light(Science & Applications)》 SCIE EI CAS CSCD 2023年第1期118-127,共10页
Active metasurfaces are emerging as the core of next-generation optical devices with their tunable optical responses and flat-compact topography.Especially for the terahertz band,active metasurfaces have been develope... Active metasurfaces are emerging as the core of next-generation optical devices with their tunable optical responses and flat-compact topography.Especially for the terahertz band,active metasurfaces have been developed as fascinating devices for optical chopping and compressive sensing imaging.However,performance regulation by changing the dielectric parameters of the integrated functional materials exhibits severe limitations and parasitic losses.Here,we introduce a C-shape-split-ring-based phase discontinuity metasurface with liquid crystal elastomer as the substrate for infrared modulation of terahertz wavefront.Line-focused infrared light is applied to manipulate the deflection of the liquid crystal elastomer substrate,enabling controllable and broadband wavefront steering with a maximum output angle change of 22°at 0.68THz.Heating as another control method is also investigated and compared with infrared control.We further demonstrate the performance of liquid crystal elastomer metasurface as a beam steerer,frequency modulator,and tunable beam splitter,which are highly desired in terahertz wireless communication and imaging systems.The proposed scheme demonstrates the promising prospects of mechanically deformable metasurfaces,thereby paving the path for the development of reconfigurable metasurfaces. 展开更多
关键词 TUNABLE MODULATOR BEAM
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Spectrally programmable Raman fiber laser with adaptive wavefront shaping 被引量:1
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作者 YANLI zhang SHANSHAN WANG +2 位作者 MINGZHU SHE YUNJIANG RAO weili zhang 《Photonics Research》 SCIE EI CAS CSCD 2023年第1期20-26,共7页
Raman fiber lasers(RFLs)have broadband tunability due to cascaded stimulated Raman scattering,providing extensive degrees of freedom for spectral manipulation.However,the spectral diversity of RFLs depends mainly on t... Raman fiber lasers(RFLs)have broadband tunability due to cascaded stimulated Raman scattering,providing extensive degrees of freedom for spectral manipulation.However,the spectral diversity of RFLs depends mainly on the wavelength flexibility of the pump,which limits the application of RFLs.Here,a spectrally programmable RFL is developed based on two-dimensional spatial-to-spectral mapping of light in multimode fibers(MMFs).Using an intracavity wavefront shaping method combined with genetic algorithm optimization,we launch light with a selected wavelength(s)at MMF output into the active part of the laser for amplification.In contrast,the light of undesired wavelengths is blocked.We demonstrate spectral shaping of the high-order RFL,including a continuously tunable single wavelength and multiple wavelengths with a designed spectral shape.Due to the simultaneous control of different wavelength regions,each order of Raman Stokes light allows flexible and independent spectral manipulation.Our research exploits light manipulation in a fiber platform with multieigenmodes and nonlinear gain,mapping spatial control to the spectral domain and extending linear light control in MMFs to active light emission,which is of great significance for applications of RFLs in optical imaging,sensing,and spectroscopy. 展开更多
关键词 FIBER LASER PUMP
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Generating superposed terahertz perfect vortices via a spin-multiplexed all-dielectric metasurface 被引量:1
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作者 FAN HUANG QUAN XU +4 位作者 WANYING LIU TONG WU JIANQIANG GU JIAGUANG HAN weili zhang 《Photonics Research》 SCIE EI CAS CSCD 2023年第3期431-441,共11页
Perfect optical vortices(POVs),characterized as a ring radius independent of topological charge(TC),possess extensive application in particle manipulation and optical communication.At present,the complex and bulky opt... Perfect optical vortices(POVs),characterized as a ring radius independent of topological charge(TC),possess extensive application in particle manipulation and optical communication.At present,the complex and bulky optical device for generating POVs has been miniaturized by leveraging the metasurface,and either spindependent or spin-independent POV conversions have been further accomplished.Nevertheless,it is still challenging to generate superposed POVs for incidences with orthogonal circular polarization.Here,a spinmultiplexed all-dielectric metasurface method for generating superposed POVs in the terahertz frequency range is proposed and demonstrated.By using the multiple meta-atom comprised structure as the basic unit,the complex amplitude of two superposed POVs is modulated,decoupled,and subsequently encoded to left-and righthanded circular polarization incidences.Furthermore,two kinds of metasurfaces are fabricated and characterized to validate this controlling method.It is demonstrated that the measured intensity and phase distributions match well with the calculation of the Rayleigh–Sommerfeld diffraction integral,and the radius of superposed POVs is independent of TCs.This work provides promising opportunities for developing ultracompact terahertz functional devices applied to complex structured light generation and terahertz communication,and exploring sophisticated spin angular momentum and orbital angular momentum interactions like the photonic spin-Hall effect. 展开更多
关键词 DIELECTRIC RADIUS GENERATING
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Meta-optics inspired surface plasmon devices 被引量:1
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作者 Quan Xu Yuanhao Lang +8 位作者 Xiaohan Jiang Xinyao Yuan Yuehong Xu Jianqiang Gu Zhen Tian Chunmei Ouyang Xueqian zhang Jiaguang Han weili zhang 《Photonics Insights》 2023年第1期48-91,共44页
Surface plasmons(SPs)are electromagnetic surface waves that propagate at the interface between a conductor and a dielectric.Due to their unique ability to concentrate light on two-dimensional platforms and produce ver... Surface plasmons(SPs)are electromagnetic surface waves that propagate at the interface between a conductor and a dielectric.Due to their unique ability to concentrate light on two-dimensional platforms and produce very high local-field intensity,SPs have rapidly fueled a variety of fundamental advances and practical applications.In parallel,the development of metamaterials and metasurfaces has rapidly revolutionized the design concepts of traditional optical devices,fostering the exciting field of meta-optics.This review focuses on recent progress of meta-optics inspired SP devices,which are implemented by the careful design of subwavelength structures and the arrangement of their spatial distributions.Devices of general interest,including coupling devices,on-chip tailoring devices,and decoupling devices,as well as nascent SP applications empowered by sophisticated usage of meta-optics,are introduced and discussed. 展开更多
关键词 surface plasmons METAMATERIALS metasurfaces PLASMONICS metadevices
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High-voltage,low-temperature supercapacitors enabled by localized“water-in-pyrrolidinium chloride”electrolyte
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作者 Peng zhang weili zhang +8 位作者 Zhengjie Wang Xuefei Wang Qingjuan Ren Shuai zhang Yujia Wang Liang He Pan Liu Qingyin zhang Zhiqiang Shi 《eScience》 2023年第6期80-88,共9页
Aqueous electrolytes offer superior prospects for advanced energy storage.“Water-in-salt”(WIS)electrolytes exhibit a wide electrochemical stability window(ESW),but their low conductivity,high viscosity,and precipita... Aqueous electrolytes offer superior prospects for advanced energy storage.“Water-in-salt”(WIS)electrolytes exhibit a wide electrochemical stability window(ESW),but their low conductivity,high viscosity,and precipitation at low temperatures restrict their application.Herein,we report a novel localized“water-in-pyrrolidinium chloride”electrolyte(LWIP;1 mol/L,N-propyl-N-methylpyrrolidinium chloride/(water and N,Ndimethylformamide,1:4 by molality))enabling high-voltage,low-temperature supercapacitors(SCs).The greatly improved ESW(3.451 V)is mainly attributed to the strong solvation between Cl-and water molecules,which broadens the negative stability.This water-binding mechanism is very different from that of a WIS electrolyte based on alkali metal salt.SCs using LWIP electrolytes not only yield a high operating voltage of 2.4 V and excellent capacity retention(82.8%after 15,000 cycles at 5 A g^(-1))but also operate stably at-20℃.This work provides new approaches for the design and preparation of novel electrolytes. 展开更多
关键词 Localized“water-in-pyrrolidinium chloride” electrolyte High voltage Low temperature Aqueous supercapacitors High power/energy density
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INTERACTIVE KNOWLEDGE LEARNING BY ARTIFICIAL INTELLIGENCE FOR SMALLHOLDERS
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作者 weili zhang Renlian zhang +2 位作者 Hongjie JI Anja SEVERIN Zhaojun LI 《Frontiers of Agricultural Science and Engineering》 CSCD 2023年第4期648-653,共6页
Enhancement of farming management relies heavily on enhancing farmer knowledge.In the past,both the direct learning approach and the personnel extension system for improving fertilization practices of smallholders has... Enhancement of farming management relies heavily on enhancing farmer knowledge.In the past,both the direct learning approach and the personnel extension system for improving fertilization practices of smallholders has proven insufficiently effective.Therefore,this article proposes an interactive knowledge learning approach using artificial intelligence as a promising alternative.The system consists of two parts.The first is a dialog interface that accepts information from farmers about their current farming practices.The second part is an intelligent decision system,which categorizes the information provided by farmers in two categories.The first consists of onfarm constraints,such as fertilizer resources,split application times and seasons.The second comprises knowledge-based practices by farmers,such as nutrient in-and output balance,ratios of different nutrients and the ratios of each split nutrient amount to the total nutrient input.The interactive knowledge learning approach aims to identify and rectify incorrect practices in the knowledge-based category while considering the farmer's available finance,labor,and fertilizer resources.Investigations show that the interactive knowledge learning approach can make a strong contribution to prevention of the overuse of nitrogen and phosphorus fertilizers,and mitigating agricultural non-point sourcepollution. 展开更多
关键词 FINANCE PREVENTION FARMING
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Composition and Functional Capacity of Gut Microbes are Associated with Arterial Stiffness:A Prospective Study
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作者 Jing Li Yixuan Zhong +4 位作者 Jingjing Bai Shuohua Chen Jun Cai Shouling Wu weili zhang 《Cardiology Discovery》 2023年第2期102-111,共10页
Objective:Arterial stiffness is an important predictor of cardiovascular disease.Microbial diversity in the gut has been shown to be associated inversely with arterial stiffness in Caucasian populations.However,due to... Objective:Arterial stiffness is an important predictor of cardiovascular disease.Microbial diversity in the gut has been shown to be associated inversely with arterial stiffness in Caucasian populations.However,due to the different profiles of the gut microbiota among ethnicities,the relationship between gut-microbiota dysbiosis and the progression of arterial stiffness merits further investigation.This study aimed to investigate the association between the composition and functional capacity of the gut microbiota and the progression of arterial stiffness.Methods:“Shotgun”metagenomics sequencing were undertaken in 96 individuals from a hypertension-associated gut-microbiota study in the Kailuan cohort,who measured brachial-ankle pulse wave velocity(baPWV)and provided fecal samples between September 2014 and February 2015 at Kailuan General Hospital and 11 affiliated hospitals.The different composition and functional capacity of the gut microbiota were compared between individuals without arterial stiffness(normal arterial stiffness group,baPWV<1,400 cm/s,n=27)and participants with arterial stiffness(increased arterial stiffness group,baPWV≥1,400 cm/s,n=69)at baseline.These participants were followed up prospectively for a mean duration of 2.6 years,and 50 underwent a repeat baPWV measurement.Associations between the gut microbiota and severity and progression of arterial stiffness were assessed using MaAsLin2 software after adjustment for age,sex,and mean arterial blood pressure and correction for multiple testing.Gene“catalogs”were aligned to the Kyoto Encyclopedia of Genes and Genomes(KEGG)database to obtain information for potential functional capacities of the gut microbiota.Results:In this study,14 genera and 50 species of bacteria were identified to be abundant in participants with normal arterial stiffness compared with those with increased arterial stiffness.Of 14 genera,the prevalence of beneficial bacteria of the genera Leadbetterella and Cytophaga was correlated inversely with baPWV(P<0.05).Analyses of functional capacity revealed gut-microbial dysfunctions in the synthetic processes of“threonine dehydratase”“hypothetical protein”“mannosyl transferase”and“type-IV secretion-system proteins”in individuals suffering from arterial stiffness.During follow-up,bacteria of the proinflammatory genera Escherichia,Shigella,and Ruegeria were enriched in individuals with increased baPWV.Functional analyses showed that 26 KEGG orthologs of gut microbes were associated with an increase in baPWV and involved in“carbohydrate metabolism”“amino acid metabolism”and“protein families related to genetic information processing.”Conclusions:The composition and functional capacity of the microbial community in the gut of people suffering from arterial stiffness differed from those in individuals not suffering from arterial stiffness.Our data provide a new direction for the causality of the host-gut microbiota in arterial stiffness. 展开更多
关键词 Arterial stiffness Brachial-ankle pulse wave velocity Gut microbiota Microbial functions
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嗅神经母细胞瘤术后放疗致鼻泪管狭窄一例
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作者 章伟利 吴蓉 +1 位作者 黄钦颖 李金瑛 《中华眼视光学与视觉科学杂志》 CAS CSCD 2019年第12期955-955,共1页
患者,女,37岁,因"右侧鼻塞、脓涕、嗅觉减退1年"于2016年10月31日到北京大学深圳医院(以下简称我院)耳鼻喉科就诊,查鼻窦CT提示:右侧上、中鼻道内占位性病变,符合嗅母细胞瘤改变。2016年11月4日在我院耳鼻喉科住院并在全身麻... 患者,女,37岁,因"右侧鼻塞、脓涕、嗅觉减退1年"于2016年10月31日到北京大学深圳医院(以下简称我院)耳鼻喉科就诊,查鼻窦CT提示:右侧上、中鼻道内占位性病变,符合嗅母细胞瘤改变。2016年11月4日在我院耳鼻喉科住院并在全身麻醉下行右侧经鼻鼻腔鼻窦肿瘤切除术,术后病理提示:右侧嗅神经母细胞瘤。 展开更多
关键词 嗅神经母细胞瘤 嗅觉减退 术后放疗 中鼻道 占位性病变 鼻腔鼻窦肿瘤 鼻泪管狭窄 耳鼻喉科
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