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Knockdown of RNA N6-methyladenosine methyltransferase METTL3 represses Warburg effect in colorectal cancer via regulating HIF-1a 被引量:2
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作者 Zhou Yang Yingjun Quan +7 位作者 yusheng Chen Yijun Huang Renhong Huang weiping yu Dejun Wu Min Ye Zhijun Min Bo yu 《Signal Transduction and Targeted Therapy》 SCIE CSCD 2021年第3期624-626,共3页
Dear Editor,Colorectal cancer(CRC)is an important digestive tract tumor with high malignancy.Nearly one million people suffer from CRC every year with a mortality rate of 33%.Therefore,it is urgent to determine the me... Dear Editor,Colorectal cancer(CRC)is an important digestive tract tumor with high malignancy.Nearly one million people suffer from CRC every year with a mortality rate of 33%.Therefore,it is urgent to determine the mechanism for the development of CRC,in order to find more effective diagnosis markers and therapeutic targets.Various RNA modifications have been identified in both mRNA and non-coding RNAs,with RNA methylation being the most common mRNA modification in eukaryotes. 展开更多
关键词 cancer diagnosis MORTALITY
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Ceramic coating electric-deposited by high-energy pulse 被引量:1
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作者 weiping yu Xiaoping Wang 《Chinese Science Bulletin》 SCIE EI CAS 1999年第24期2228-2232,共5页
A novel method to prepare ceramic coatings has been developed by making use of plasma energy produced from the pulsed discharge between electric conductor and aqueous electrolyte. A ZrO2-8%Y2O3 coating was obtained by... A novel method to prepare ceramic coatings has been developed by making use of plasma energy produced from the pulsed discharge between electric conductor and aqueous electrolyte. A ZrO2-8%Y2O3 coating was obtained by this method, which had excellent adhesion with substrate, smooth surface and good resistance to high temperature oxidation. 展开更多
关键词 HIGH-ENERGY PULSE electric-deposition CERAMIC coating.
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