Introduction:The Omicron variant of severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)demonstrates increased transmissibility compared to earlier strains,contributing to a significant number of fatalities in ...Introduction:The Omicron variant of severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)demonstrates increased transmissibility compared to earlier strains,contributing to a significant number of fatalities in Hong Kong Special Administrative Region(HKSAR),China.Adequate medical resources and medications are essential in mitigating these deaths.This study evaluates the effects of supplementary resources from the Chinese mainland during the fifth wave of the pandemic in HKSAR.Methods:Vector autoregression(VAR)was employed to analyze data from the Oxford coronavirus disease 2019(COVID-19)Government Response Tracker to assess the effectiveness of control measures during five waves of the pandemic in HKSAR.Additionally,a transmission dynamics model was created to investigate the influence of supplementary medical resources from the Chinese mainland and oral medications on mortality.Results:In the initial four waves,workplace closures,restrictions on public events,international travel bans,and shielding the elderly significantly influenced pandemic management.Contrarily,during the fifth wave,these measures showed no notable effects.When comparing a situation without extra medical resources or COVID-19 oral medication,there was a 17.7%decrease in COVID-19 fatalities with mainland medical resources and an additional 10.2%reduction with oral medications.Together,they contributed to a 26.6%decline in fatalities.Discussion:With the rapid spread of the virus,regional reallocation of medical resources may reduce mortality even when the local healthcare system is overstretched.展开更多
基金Supported by the National Key Research and Development Program of China(No.2022YFC2600705)the Self-supporting Program of Guangzhou Laboratory(Grant No.SRPG22-007)+2 种基金the Science and Technology Development Fund of Macao SAR,China(005/2022/ALC and 0045/2021/A)the Science and Technology Program of Guangzhou(No.2022B01W0003 and Grant No.202102100003)the Macao University of Science and Technology(Grant FRG-20-021-MISE).
文摘Introduction:The Omicron variant of severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)demonstrates increased transmissibility compared to earlier strains,contributing to a significant number of fatalities in Hong Kong Special Administrative Region(HKSAR),China.Adequate medical resources and medications are essential in mitigating these deaths.This study evaluates the effects of supplementary resources from the Chinese mainland during the fifth wave of the pandemic in HKSAR.Methods:Vector autoregression(VAR)was employed to analyze data from the Oxford coronavirus disease 2019(COVID-19)Government Response Tracker to assess the effectiveness of control measures during five waves of the pandemic in HKSAR.Additionally,a transmission dynamics model was created to investigate the influence of supplementary medical resources from the Chinese mainland and oral medications on mortality.Results:In the initial four waves,workplace closures,restrictions on public events,international travel bans,and shielding the elderly significantly influenced pandemic management.Contrarily,during the fifth wave,these measures showed no notable effects.When comparing a situation without extra medical resources or COVID-19 oral medication,there was a 17.7%decrease in COVID-19 fatalities with mainland medical resources and an additional 10.2%reduction with oral medications.Together,they contributed to a 26.6%decline in fatalities.Discussion:With the rapid spread of the virus,regional reallocation of medical resources may reduce mortality even when the local healthcare system is overstretched.
