PURPOSE: It is unclear whether protein C deficiency is associated with retinal venous occlusive disease. DESIGN: We performed a cross-sectional study. METHODS: Members of a protein C-deficient family, either deficient...PURPOSE: It is unclear whether protein C deficiency is associated with retinal venous occlusive disease. DESIGN: We performed a cross-sectional study. METHODS: Members of a protein C-deficient family, either deficient or nondeficient, with a history of nonocular venous thrombosis were included. All participants completed questionnaires regarding their medical and ophthalmic histories. Each subject underwent dilated direct ophthalmoscopic and binocular indirect ophthalmoscopic examinations by a single vitreoretinal specialist. RESULTS: None of the 18 family members with a known history of nonocular thrombosis-12 with and 6 without protein C deficiency-manifested stigmas of recent or chronic retinal vascular occlusive disease. CONCLUSIONS: This study showed no evidence of involvement of the retinal vascular bed in a family with an increased risk of nonocular venous thrombosis attributable to the deficiency of protein C.展开更多
Background/aim: A lack of data exists concerning the development of late posto perative, non-proliferative vitreoretinopathy (PVR), rhegmatogenous retinal det achments (RRDs) after successful posterior segment intraoc...Background/aim: A lack of data exists concerning the development of late posto perative, non-proliferative vitreoretinopathy (PVR), rhegmatogenous retinal det achments (RRDs) after successful posterior segment intraocular foreign body (PSI OFB) removal. The authors present a series of PSIOFB cases over several years wi th posterior hyaloid separation resulting in RRD in two patients, 4 and 8 months after initial injury and vitrectomy. This report aims to increase aware ness concerning the possibility of late RRDs complicating PSIOFB injuries and to emphasise careful long term observation. Methods: Medical records of consecutiv e cases referred for presumed PSIOFB injury during a 4 year period were retrospe ctively reviewed. All eyes referred for presumed PSIOFB injuries were included. Results: 11 patients were included in the series. Two patients had eyes so badly injured by large PSIOFBs that primary globe closure was followed within days by enucleation. Nine patients underwent pars plana vitrectomy for PSIOFB removal. Two patients experienced late RRDs that were managed with excellent long term vi sual outcomes. Conclusions: Late RRD may occur following successful removal of P SIOFBs, even several months after initial management. These RRDs may be successf ully managed with a variety of methods, depending upon the extent and location o f the detachment and causative break as well as surgeon comfort and preference.展开更多
文摘PURPOSE: It is unclear whether protein C deficiency is associated with retinal venous occlusive disease. DESIGN: We performed a cross-sectional study. METHODS: Members of a protein C-deficient family, either deficient or nondeficient, with a history of nonocular venous thrombosis were included. All participants completed questionnaires regarding their medical and ophthalmic histories. Each subject underwent dilated direct ophthalmoscopic and binocular indirect ophthalmoscopic examinations by a single vitreoretinal specialist. RESULTS: None of the 18 family members with a known history of nonocular thrombosis-12 with and 6 without protein C deficiency-manifested stigmas of recent or chronic retinal vascular occlusive disease. CONCLUSIONS: This study showed no evidence of involvement of the retinal vascular bed in a family with an increased risk of nonocular venous thrombosis attributable to the deficiency of protein C.
文摘Background/aim: A lack of data exists concerning the development of late posto perative, non-proliferative vitreoretinopathy (PVR), rhegmatogenous retinal det achments (RRDs) after successful posterior segment intraocular foreign body (PSI OFB) removal. The authors present a series of PSIOFB cases over several years wi th posterior hyaloid separation resulting in RRD in two patients, 4 and 8 months after initial injury and vitrectomy. This report aims to increase aware ness concerning the possibility of late RRDs complicating PSIOFB injuries and to emphasise careful long term observation. Methods: Medical records of consecutiv e cases referred for presumed PSIOFB injury during a 4 year period were retrospe ctively reviewed. All eyes referred for presumed PSIOFB injuries were included. Results: 11 patients were included in the series. Two patients had eyes so badly injured by large PSIOFBs that primary globe closure was followed within days by enucleation. Nine patients underwent pars plana vitrectomy for PSIOFB removal. Two patients experienced late RRDs that were managed with excellent long term vi sual outcomes. Conclusions: Late RRD may occur following successful removal of P SIOFBs, even several months after initial management. These RRDs may be successf ully managed with a variety of methods, depending upon the extent and location o f the detachment and causative break as well as surgeon comfort and preference.
