Experimental study on prediction model of wet gas pressure drop across single-orifice plate in horizontal pipes in the low gas phase Froude number region

The pressure drop prediction of wet gas across single-orifice plate in horizontal pipes had been solved satisfactorily under an annular-mist flow in the upstream of orifice plates.However,this pressure drop prediction is still not clearly determined when the upstream is in an intermittent flow or stratified flow,which is corresponding to a region of low FrG(gas phase Froude number)in the flow pattern map of wet gases.In this study,the wet gas pressure drop across a single-orifice plate was experimentally investigated in the low FrG region.By the experiment,the flow pattern transition in the downstream of single-orifice plates,as well as the effects of FrG and FrL(liquid phase Froude number)on UG(gas phase multiplier),were determined and compared when the upstream is in the flow pattern transition and the stratified flow region,respectively.Prediction performances were examined on the available pressure drop models.It was found that no model could be capable of jointly predicting the wet gas pressure drop in the low FrG region with an acceptable accuracy.With a new method of correlating FrG and FrL simultaneously,new correlations were proposed for the low FrG region.Among which the modified Chisholm model shows the best prediction accuracies,with the prediction deviations of UG being within 7%and 3%when the upstream is in flow pattern transition and stratified flow region,respectively.

Bioceramic-based scaffolds with antibacterial function for bone tissue engineering:A review

Bone defects caused by trauma,tumor,congenital abnormality and osteoarthritis,etc.have been substantially impacted the lives and health of human.Artificial bone implants,like bioceramic-based scaffolds,provide significant benefits over biological counterparts and are critical for bone repair and regeneration.However,it is highly probable that bacterial infections occur in the surgical procedures or on bioceramic-based scaffolds.Therefore,it is of great significance to obtain bioceramic-based scaffolds with integrative antibacterial and osteogenic functions for treating bone implant-associated infection and promoting bone repair.To fight against infection problems,bioceramic-based scaffolds with various antibacterial strategies are developed for bone repair and regeneration and also have made great progresses.This review summarizes recent progresses in bioceramic-based scaffolds with antibacterial function,which include drug-induced,ion-mediated,physical-activated and their combined antibacterial strategies according to specific antibacterial mechanism.Finally,the challenges and opportunities of antibacterial bioceramic-based scaffolds are discussed.

Forsterite-hydroxyapatite composite scaffolds with photothermal antibacterial activity for bone repair

Bone engineering scaffolds with antibacterial activity satisfy the repair of bacterial infected bone defects,which is an expected issue in clinical.In this work,3D-printed polymer-derived forsterite scaffolds were proposed to be deposited with hydroxyapatite(HA)coating via a hydrothermal treatment,achieving the functions of photothermal-induced antibacterial ability and bioactivity.The results showed that polymer-derived forsterite scaffolds possessed the photothermal antibacterial ability to inhibit Staphylococcus aureus(S.aureus)and Escherichia coli(E.coli)in vitro,owing to the photothermal effect of free carbon embedded in the scaffolds.The morphology of HA coating on forsterite scaffolds could be controlled through changing the hydrothermal temperature and the pH value of the reaction solution during hydrothermal treatment.Furthermore,HA coating did not influence the mechanical strength and photothermal effect of the scaffolds,but facilitated the proliferation and osteogenic differentiation of rat bone mesenchymal stem cells(rBMSCs)on scaffolds.Hence,the HA-deposited forsterite scaffolds would be greatly promising for repairing bacterial infected bone defects.