Influence of initial check, information exchange, final accuracy check, reaction information nursing on the psychology of elderly with lung cancer

BACKGROUND As one of the fatal diseases with high incidence,lung cancer has seriously endangered public health and safety.Elderly patients usually have poor self-care and are more likely to show a series of psychological problems.AIM To investigate the effectiveness of the initial check,information exchange,final accuracy check,reaction(IIFAR)information care model on the mental health status of elderly patients with lung cancer.METHODS This study is a single-centre study.We randomly recruited 60 elderly patients with lung cancer who attended our hospital from January 2021 to January 2022.These elderly patients with lung cancer were randomly divided into two groups,with the control group taking the conventional propaganda and education and the observation group taking the IIFAR information care model based on the conventional care protocol.The differences in psychological distress,anxiety and depression,life quality,fatigue,and the locus of control in psychology were compared between these two groups,and the causes of psychological distress were analyzed.RESULTS After the intervention,Distress Thermometer,Hospital Anxiety and Depression Scale(HADS)for anxiety and the HADS for depression,Revised Piper’s Fatigue Scale,and Chance Health Locus of Control scores were lower in the observation group compared to the pre-intervention period in the same group and were significantly lower in the observation group compared to those of the control group(P<0.05).After the intervention,Quality of Life Questionnaire Core 30(QLQ-C30),Internal Health Locus of Control,and Powerful Others Health Locus of Control scores were significantly higher in the observation and the control groups compared to the pre-intervention period in their same group,and QLQ-C30 scores were significantly higher in the observation group compared to those of the control group(P<0.05).CONCLUSION The IIFAR information care model can help elderly patients with lung cancer by reducing their anxiety and depression,psychological distress,and fatigue,improving their tendencies on the locus of control in psychology,and enhancing their life qualities.

A molecular probe carrying anti-tropomyosin 4 for early diagnosis of cerebral ischemia/reperfusion injury

In vivo imaging of cerebral ischemia/reperfusion injury remains an important challenge.We injected porous Ag/Au@SiO_(2) bimetallic hollow nanoshells carrying anti-tropomyosin 4 as a molecular probe into mice with cerebral ischemia/reperfusion injury and observed microvascular changes in the brain using photoacoustic imaging with ultrasonography.At each measured time point,the total photoacoustic signal was significantly higher on the affected side than on the healthy side.Twelve hours after reperfusion,cerebral perfusion on the affected side increased,cerebrovascular injury worsened,and anti-tropomyosin 4 expression increased.Twenty-four hours after reperfusion and later,perfusion on the affected side declined slowly and stabilized after 1 week;brain injury was also alleviated.Histopathological and immunohistochemical examinations confirmed the brain injury tissue changes.The nanoshell molecular probe carrying anti-tropomyosin 4 has potential for use in early diagnosis of cerebral ischemia/reperfusion injury and evaluating its progression.

Dynamics and controls of ecosystem multiserviceability across the Qingzang Plateau

Ecosystem multiserviceability(EMS),a comprehensive and significant ecological indicator,reflects the capacity of ecosystems to offer multiple services concurrently.Intensified climate change and human activity are continu-ously altering ecosystem functions,services,and EMSs.However,numerous studies have only focused on one or a few ecosystem services,rarely taking into account spatial-temporal distribution and drivers of EMS on behalf of different agencies.We calculated EMS including pastoralist(PA),environmental protection agency(EPA),bio-diversity conservation agency(BCA),and climate change mitigation agency(CCMA)using grassland production,habitat quality,water conservation,and carbon sequestration.Then,the effects of geographical features,climate factors,and human activities on spatial-temporal patterns of EMS were explored.The result indicated that EMS showed a decreasing tendency from the southeast to northwest on the Qingzang Plateau(QZP).Meanwhile,there were no obvious fluctuations in four simulated scenarios(PA,EPA,BCA and CCMA)among different vegetation types during 2000 to 2015.Notably,EMS of all simulated scenarios decreased in the alpine steppe ecosystem,but negligible changes were found in other ecosystems from 2015 to 2020.Moreover,the relative importance of precipitation in annual mean value(from 2000 to 2020)of PA,EPA,BCA and CCMA were 0.13,0.11,0.30 and 0.19,respectively.Overall,precipitation played the dominant role on the dynamics of EMS,followed by elevation and human footprint.Our findings highlighted that understanding the patterns and drivers of EMS could provide a reference for the regional management and maintenance of ecosystem stability on QZP.

Simulation study on the influence of longitudinal dynamic force on extreme-long heavy-haul trains

Purpose–The objective of this study is to investigate the impact of longitudinal forces on extreme-long heavy-haul trains,providing new insights and methods for their design and operation,thereby enhancing safety,operational efficiency and track system design.Design/methodology/approach–A longitudinal dynamics simulation model of the super long heavy haul train was established and verified by the braking test data of 30,000 t heavy-haul combination train on the long and steep down grade of Daqing Line.The simulation model was used to analyze the influence of factors on the longitudinal force of super long heavy haul train.Findings–Under normal conditions,the formation length of extreme-long heavy-haul combined train has a small effect on the maximum longitudinal coupler force under full service braking and emergency braking on the straight line.The slope difference of the long and steep down grade has a great impact on the maximum longitudinal coupler force of the extreme-long heavy-haul trains.Under the condition that the longitudinal force does not exceed the safety limit of 2,250 kN under full service braking at the speed of 60 km/h the maximum allowable slope difference of long and steep down grade for 40,000 t super long heavy-haul combined trains is 13‰,and that of 100,000 t is only 5‰.Originality/value–The results will provide important theoretical basis and practical guidance for further improving the transportation efficiency and safety of extreme-long heavy-haul trains.

Sweet综合征的发病机制及治疗进展

Sweet综合征(Sweet syndrome, SS)是一种病因不明的炎症性嗜中性皮肤病,与感染、药物、肿瘤及自身免疫性疾病等相关。发病机制涉及中性粒细胞功能障碍、免疫失衡及遗传因素等。传统一线治疗首选系统应用糖皮质激素。近年来随着SS的研究取得一定进展,生物制剂及小分子靶向药物也有成功治疗SS的报道。本文就SS的发病机制及治疗进展作一综述。

儿童错(牙合)畸形合并阻塞性睡眠呼吸暂停综合征的诊疗研究进展

儿童错(牙合)畸形在口腔科较常见,而部分错(牙合)畸形合并有阻塞性睡眠呼吸暂停综合征(obstructive sleep apnea hypopnea syndrome,OSAHS)的儿童常由于缺乏多学科诊疗而未得到恰当的治疗,导致睡眠期间通气异常,影响儿童中枢系统、心血管发育,甚至产生神经行为问题。儿童OSAHS与上呼吸道结构变窄、面部骨骼和神经肌肉因素相关,与错(牙合)畸形有一定相关性;儿童OSAHS临床表现和病因多样,因此诊断和治疗呈现多学科交叉、个性化和专业化的特点。通过问卷和体格检查能够进行初步筛查,儿童口腔科和耳鼻喉科检查则是发现该疾病的前哨。多导睡眠监测(polysomnography,PSG)是目前诊断的直接方法。儿童OSAHS治疗方法多样,对因腺样体扁桃体肥大引起的OSAHS,以腺样体扁桃体切除术为主;下颌前导装置治疗、上颌扩弓治疗等正畸治疗对合并错(牙合)畸形的OSAHS儿童有较好效果。目前儿童错(牙合)畸形与OSAHS相关性的研究较少,多学科联合疗法可能会提高治愈率但缺乏足够文献证明。未来应进一步阐明OSAHS的发病机制,推进多学科联合治疗的研究,以期通过多学科协作,对于潜在及已发病患者做到早干预、早治疗。

胜金口7号佛寺伎乐童子图像抱持乐器考辨

德国探险队第二次吐鲁番考察时,在胜金口7号佛寺获得一持花菩萨的壁画图像,图像中随侍的伎乐童子所抱持乐器由于其音柱制度之特殊,对琵琶乐器发展历史的研究具有极珍贵的价值。然而由于画工对琴轸部分的省略,导致这件乐器在1913年壁画图像公之于世时,被剥取者勒柯克(AlbertvonLeCoq)错误地鉴定为中亚的近古乐器dutar(都塔尔)。通过乐器发展历史的追溯,对勒柯克的误判予以证伪,并结合乐器学及音乐史的分析,指出壁画所描绘的乐器形象属于中古时期短颈品柱类鲁特(short-neckedfretted lute)——中国所称琵琶——的一种,其“真相”为中国五代时期前后的直项五弦琵琶。

老旧小区建筑结构及市政设施改造研究综述

本研究旨在探讨老旧小区构成及其更新需求的识别,通过分析不同时期老旧小区的构成特点,明确更新工作的主导方向及实施重点,进而提出完善老旧小区更新需求识别的策略。首先梳理了老旧小区在不同时期的构成主体,包括公有产权房屋、商品房和保障房等。随后,从建筑生命周期和当前需求差距的角度,分析了老旧小区更新需求的识别方法。在此基础上,提出应由产权方主导进行相关工作,并对客观运行状况与当前需求差距较大的老旧小区开展更新工作。研究发现,老旧小区的构成在不同时期呈现出不同的特点,当前以公有产权房屋为主体,未来商品房和保障房将逐渐占据重要地位。在更新需求识别方面,研究强调了从建筑生命周期和当前需求差距两个维度进行综合评估的重要性。同时,明确了产权方在更新工作中的主导地位,以及针对特定老旧小区开展更新工作的必要性。为完善老旧小区更新需求的识别,应充分考虑不同时期的构成特点和管理制度,从建筑生命周期和当前需求差距的角度进行综合评估。同时,强化产权方在更新工作中的主导作用,针对运行状况与需求差距较大的老旧小区开展有针对性的更新工作,以提升老旧小区的整体居住环境和生活品质。

Practice guidelines for ultrasound-guided percutaneous microwave ablation for hepatic malignancy

Primary liver cancer and liver metastases are among the most frequent malignancies worldwide,with an increasing number of new cases and deaths every year.Traditional surgery is only suitable for a limited proportion of patients and imaging-guided percutaneous thermal ablation has achieved optimistic results for management of hepatic malignancy.This synopsis outlines the first clinical practice guidelines for ultrasoundguided percutaneous microwave ablation therapy for hepatic malignancy,which was created by a joint task force of the Society of Chinese Interventional Ultrasound.The guidelines aim at standardizing the microwave ablation procedure and therapeutic efficacy assessment,as well as proposing the criteria for the treatment candidates.

马铃薯StCYP85A3促进萌芽及根系伸长的功能解析

油菜素内酯(BR)是一类植物甾醇类激素,对植物生长发育及胁迫应答具有显著的调控作用,马铃薯中StCYP85A3作为BR合成酶的编码基因,功能仍待进一步探究。本研究从‘川芋10号’马铃薯中克隆出该基因,生物信息学分析表明该蛋白具有催化BR合成的典型亲氧结合域,属于CYP85As家族成员。通过组织表达分析发现该基因在块茎芽眼及根中表达量最高,且芽眼中的表达量随着储藏时间的延长而增加,在块茎芽眼休眠解除时表达迅速升高。同时发现外源BR可诱导马铃薯芽眼及根中StCYP85A3表达量升高,从而显著促进了种薯萌芽及幼苗根的伸长。通过在拟南芥野生型及cyp85a2突变体中过表达StCYP85A3发现,过表达株系种子萌发及根系伸长都早于野生型,同时回补株系弥补了突变体种子萌发、植株根系生长迟缓的缺陷。此外,外源BR对过表达株系种子萌发、根系伸长无显著促进作用,但显著促进了野生型、突变体及回补株系种子萌发、根系伸长。上述马铃薯及拟南芥试验结果表明, StCYP85A3具有促进萌芽及根系伸长的功能。

面向电气工程研究生的“数字图像处理”课程改革

人工智能技术在电气工程领域的应用日益广泛。图像处理与机器视觉作为人工智能的重要分支,在电气工程专业研究生的知识体系中的重要性在不断提高。针对这一需求,对“数字图像处理”课程进行了改革。根据电气工程专业研究生的培养目标,设计了课程的教学目标,进而根据电气工程领域对图像处理的实际需求调整了教学内容;根据电气工程领域的实际工程应用设计了具有较高复杂度的实践教学内容;改革了课程的考核方式与内容,以有效评估学生在课程中的能力达成情况。改革后的课程教学,有效提高了学生在课程和实践中的参与度,强化了实践效果,使学生在课程结束时基本具备了在电气工程领域复杂工程问题中应用和评价基于图像的解决方案能力。

Geology and mineralization of the Tiegelongnan supergiant porphyry-epithermal Cu(Au, Ag) deposit(10 Mt) in western Tibet, China: A review

The Tiegelongnan Cu(Au,Ag)deposit in central Tibet contains more than 10 Mt of copper ranking 29 th in the world.It is characterized by typical porphyry-epithermal alteration and mineralization.In order to improve the understanding of porphyry-epithermal copper deposit in Tibet,new zircon U-Pb age and sulfur isotope data along with published data in the Tiegelongnan are presented to investigate the formation and preservation mechanism.Ore-related intrusive rocks in the Tiegelongnan including Early Cretaceous(about 120 Ma)granodiorite porphyry and diorite porphyry are closely related to the northward subduction of Bangongco-Nujiang ocean.Sulfur mainly comes from deep magma,and ore-forming fluid is affected by both magmatic and meteoric water.The metallogenic setting of Tiegelongnan is consistent with those of Andean porphyry copper deposits in South America.The cover of the Meiriqiecuo Formation volcanic rocks,Lhasa-Qiangtang collision and India-Eurasian collision have significance in the preservation and uplift of the deposit.The formation,preservation and discovery of Tiegelongnan play an important role in exploration of ancient porphyry-epithermal deposits in Tibet.

Highly Stretchable Shape Memory Self-Soldering Conductive Tape with Reversible Adhesion Switched by Temperature

With practical interest in the future applications of next-generation electronic devices,it is imperative to develop new conductive interconnecting materials appropriate for modern electronic devices to replace traditional rigid solder tin and silver paste of high melting temperature or corrosive solvent requirements.Herein,we design highly stretchable shape memory self-soldering conductive(SMSC)tape with reversible adhesion switched by temperature,which is composed of silver particles encapsulated by shape memory polymer.SMSC tape has perfect shape and conductivity memory property and anti-fatigue ability even under the strain of 90%.It also exhibits an initial conductivity of 2772 S cm^(−1) and a maximum tensile strain of~100%.The maximum conductivity could be increased to 5446 S cm^(−1) by decreasing the strain to 17%.Meanwhile,SMSC tape can easily realize a heating induced reversible strong-to-weak adhe-sion transition for self-soldering circuit.The combination of stable conductivity,excellent shape memory performance,and temperature-switching reversible adhesion enables SMSC tape to serve two functions of electrode and solder simultaneously.This provides a new way for conductive interconnecting materials to meet requirements of modern electronic devices in the future.

Observation of the early blood vessels of cutaneous malignant melanoma using Swept Source Optical Coherence Tomography A ngiography(SS-OCTA)

Melanoma,characterized by high mortality,rapid development and accompanied with angio-genesis is the most typical malignant tumor in skin cancer.Hence,the detection of blood vessels is of much significanoe.The early vascular network has small scale.If we remove the tumor early and biopsy it,it will increase the spread of the cancer cells and infection and bleeding.In this case,we presented a new angiography method.A high-resolution OCT system for noninvasive an-giographic imaging of early skin melanoma-Swept Source Optical Coberence Tomography Angiography(SS-OCTA)is proposed.With a high lateral resolution of 10pm in vrivo tomographic angiography,SS-OCTA is used to image and identify the morphology of the early tumor blood vessels.In addition,a control group experiment is conducted to observe the growth of melanoma in the process of rupture,malormation of micro-vessels.The results of the analysis and statistical test(P<0.05)are statistically signifcant.

Propagation Characteristics of Partial Discharge Pulses in the Cable

In order to determine the type and location of partial discharge in cable, the effect of partial discharge (PD) pulse propagation in the cable is studied. Firstly, pulses are injected to cables of different lengths so that input and output signal can be measured at both ends of each cable. Then the transfer function of pulse propagation path can be defined. Secondly, high-voltage test is done in the cable joint with man-made defects, and typical PD waveforms are gotten. Seven parameters of waveform characteristics are calculated, including edge times, waveform shape and statistical characteristics. They are used to distinguish different types of PD or distances of the pulse propagation. Thus the efficiency of PD recognition in cable can be improved.

基于CiteSpace的绿色医院研究热点与趋势分析

自从绿色建筑被提出,绿色医院也一直是大家关注的热点。为了全面把握绿色医院领域的研究热点及趋势,文章基于CiteSpace软件,绘制关键词共现图、关键词时间线图。结果表明:关于绿色医院较为全面的探索主要集中在标准、评价指标等方面。学者对绿色医院的关注点是技术和人文,未来应结合新兴技术,打造绿色智慧医院,实现医院的可持续发展。

面向冲击负荷的新型电能表关键技术研究

非线性冲击负荷会对计量点的电流、电压及频率产生较大影响,会引起较严重的电能计量误差。在分析非线性冲击负荷对计量误差影响的基础上,建立了冲击负荷模型,给出较为精确的冲击负荷仿真方法,据此给出了新型冲击负荷电能表的设计方案和设计原理;设计了电压、电流高速AD采样电路,给出了零磁通电流互感器设计方法;提出了一种冲击负荷计量方法及算法思路,给出了基于IIR低通滤波器的冲击负荷滤波算法及具体参数,设计出新型冲击负荷电能表。在冲击负荷模型的基础上,设计了冲击负荷典型实验环境,分别在暂态冲击负荷、短时冲击负荷、长时冲击负荷等条件下对待测冲击负荷电能表进行实验,实验结果表明,所设计的新型冲击负荷电能表能准确计量冲击负荷电能。

马铃薯蔗糖磷酸合成酶StSPS1的原核表达及抗体制备

为了对马铃薯蔗糖磷酸合成酶(SPS)编码蛋白StSPS1进行原核表达及多克隆抗体制备。从四倍体马铃薯品种川芋10号的块茎中克隆出了StSPS1基因,该基因编码区全长为3165 bp,编码蛋白的长度为1055 aa。随后基于构建的His标签融合表达载体PET30a-StSPS1,进行了StSPS1蛋白的诱导、变性、纯化、复性及兔免疫试验。结果发现,StSPS1蛋白分子量约为119.62 ku,在可溶性上清中的表达极少,主要在不溶的沉淀中表达,最佳的诱导条件为37℃下用0.5或1.0 mmol/L的IPTG诱导4 h。由于StSPS1为包涵体蛋白,故对其进行包涵体变性处理,并利用His标签纯化出了与目的条带大小相符的蛋白,同时通过His抗体进行了蛋白质免疫印迹(WB)试验,发现在119.62 ku处检测到目标条带,说明StSPS1包涵体蛋白纯化成功。最后,通过将透析复性后的StSPS1蛋白注射进兔子皮下组织中,成功免疫出2个StSPS1的抗体,经过WB鉴定发现2个抗体均能在抗原和川芋10号叶片的总蛋白中杂出目标条带。综上,对马铃薯StSPS1蛋白进行了诱导及纯化,并成功制备了StSPS1蛋白的兔多克隆抗体。

矩形窗三点插值傅里叶变换高精度频率估计方法

针对电力系统信号频率估计的高准确性要求,该文提出一种基于矩形窗的三点复频域插值频率估计方法。所提出的方法首先采用矩形窗对信号加权处理,然后进行离散傅里叶变换,最后选择离散频谱中幅度最大的三根谱线进行复频域插值,得到频率估计结果。该方法同时考虑离散频谱中的正、负频谱,消除短程和长程频谱泄漏对频率估计误差的影响。采用主瓣最窄的矩形窗进行加窗,能最大程度地减少白噪声对频率估计误差的影响。仿真和实验结果表明:在不同周期和噪声强度情况下,所提出的方法均可以实现对信号频率的准确估计。在与已有的加窗插值傅里叶变换方法相比,该文所提出的插值算法抗噪性更好、频率估计误差更小,适用于对电力系统信号频率的准确估计。