3-Acetamidotropolone 1 reacted with p-substitutedbenzenediazonium chloride in pyridine to afford 3-acetamido-5-(4-substitutedphenylazo)tropolones 2a~f. Hydrolysis of compounds 2a~f gave 3-amino-5-(4-substitutedphenyla...3-Acetamidotropolone 1 reacted with p-substitutedbenzenediazonium chloride in pyridine to afford 3-acetamido-5-(4-substitutedphenylazo)tropolones 2a~f. Hydrolysis of compounds 2a~f gave 3-amino-5-(4-substitutedphenylazo)tropolones 3a~f which could not be obtained directly from reactions of 3-aminotropolone with p-substitutedbenzenediazonium chloride. The structures of these new compounds 2a, 2c~f, 3a, 3c~f were confirmed from the elemental analysis and spectral data.展开更多
new method to synthesize heterocycle-fused troponoid compounds by oxidizing azocoupling products of 3-isopropenyltropolone and 3-cinnamoyltropolone with bromine in the presence of pyridine was reported for the first t...new method to synthesize heterocycle-fused troponoid compounds by oxidizing azocoupling products of 3-isopropenyltropolone and 3-cinnamoyltropolone with bromine in the presence of pyridine was reported for the first time. Reaction of azo-couping products of 3-isopropenyl tropolone 1a similar to f and 3-cinnamoyltropolone 3a similar to d with excess bromine afforded heterocycle-fused troponoid compounds 2a similar to f, 4a similar to d, respectively.展开更多
3-Acetyltropolone 1 reacted with 3,4,5-trimethoxybenzaldehyde et al. to afford 2 similar to 5. 2-Acetyl-7-methylaminotropone 7 reacted with 3, 1,5-trimethoxybenzaldehyde el al, to gave 8 similar to 10. Compound 1 reac...3-Acetyltropolone 1 reacted with 3,4,5-trimethoxybenzaldehyde et al. to afford 2 similar to 5. 2-Acetyl-7-methylaminotropone 7 reacted with 3, 1,5-trimethoxybenzaldehyde el al, to gave 8 similar to 10. Compound 1 reacted with 3,4,5-trimethoxybenzaldehyde in the presence of ethyl orthoformate and perchloric acid to afford 6. Compounds 3,5 reacted with hydroxylamine to give 11, 12. The reactions of 3,5 with phenylhydrazine gave 13, 14.展开更多
基金The National Natural Science Foundation of China (29933050) and Natural Science Foundation of Liaoning Province (972004).
文摘3-Acetamidotropolone 1 reacted with p-substitutedbenzenediazonium chloride in pyridine to afford 3-acetamido-5-(4-substitutedphenylazo)tropolones 2a~f. Hydrolysis of compounds 2a~f gave 3-amino-5-(4-substitutedphenylazo)tropolones 3a~f which could not be obtained directly from reactions of 3-aminotropolone with p-substitutedbenzenediazonium chloride. The structures of these new compounds 2a, 2c~f, 3a, 3c~f were confirmed from the elemental analysis and spectral data.
文摘new method to synthesize heterocycle-fused troponoid compounds by oxidizing azocoupling products of 3-isopropenyltropolone and 3-cinnamoyltropolone with bromine in the presence of pyridine was reported for the first time. Reaction of azo-couping products of 3-isopropenyl tropolone 1a similar to f and 3-cinnamoyltropolone 3a similar to d with excess bromine afforded heterocycle-fused troponoid compounds 2a similar to f, 4a similar to d, respectively.
文摘3-Acetyltropolone 1 reacted with 3,4,5-trimethoxybenzaldehyde et al. to afford 2 similar to 5. 2-Acetyl-7-methylaminotropone 7 reacted with 3, 1,5-trimethoxybenzaldehyde el al, to gave 8 similar to 10. Compound 1 reacted with 3,4,5-trimethoxybenzaldehyde in the presence of ethyl orthoformate and perchloric acid to afford 6. Compounds 3,5 reacted with hydroxylamine to give 11, 12. The reactions of 3,5 with phenylhydrazine gave 13, 14.
