Methyl 3-deoxy-3-(diphenylphosphino)-4,6-O-benzylidene-alpha-D-altropyranoside (1) and methyl 2-deoxy-2-(diphenylphosphino)-4,6-O-benzylidene-alpha-D-altropyranoside (2) were prepared from methyl 2,3-anhydro-4,6-O-ben...Methyl 3-deoxy-3-(diphenylphosphino)-4,6-O-benzylidene-alpha-D-altropyranoside (1) and methyl 2-deoxy-2-(diphenylphosphino)-4,6-O-benzylidene-alpha-D-altropyranoside (2) were prepared from methyl 2,3-anhydro-4,6-O-benzylidene-O-D-mannopyranoside and methyl 2,3-anhydro-4,6-O-benzylidene-alpha-D-allopyranoside, respectively, via regioselective and stereospecific ring-opening reactions in high yields. Compounds 1 and 2 were oxidized to give the corresponding phosphine oxides (3 and 4).展开更多
基金Project supported by the State Key Project for Fundamental Research and the National Natural Science Foundation of China.
文摘Methyl 3-deoxy-3-(diphenylphosphino)-4,6-O-benzylidene-alpha-D-altropyranoside (1) and methyl 2-deoxy-2-(diphenylphosphino)-4,6-O-benzylidene-alpha-D-altropyranoside (2) were prepared from methyl 2,3-anhydro-4,6-O-benzylidene-O-D-mannopyranoside and methyl 2,3-anhydro-4,6-O-benzylidene-alpha-D-allopyranoside, respectively, via regioselective and stereospecific ring-opening reactions in high yields. Compounds 1 and 2 were oxidized to give the corresponding phosphine oxides (3 and 4).
