Coronary artery calcification is common in eld-erly,diabetic,and dialysis-dependent patie-nts,poses a great challenge to interventional therapy and significantly increases the risk of complica-tions and poor prognosis...Coronary artery calcification is common in eld-erly,diabetic,and dialysis-dependent patie-nts,poses a great challenge to interventional therapy and significantly increases the risk of complica-tions and poor prognosis.[1]Traditional rotational ath-erectomy and excimer laser coronary atherectomy are bo-th special treatment techniques for severely calcified le-sions,but they are difficult to use in clinical practice due to complicated operations.Intravascular lithotripsy(IVL)is a new way of treating calcified lesion.展开更多
Objective:Colorectal cancer(CRC)is one of the most lethal and prevalent malignancies world-wide.Currently,surgery,radiotherapy and chemotherapy are clinically applied as common approaches for CRC patients.Cisplatin is...Objective:Colorectal cancer(CRC)is one of the most lethal and prevalent malignancies world-wide.Currently,surgery,radiotherapy and chemotherapy are clinically applied as common approaches for CRC patients.Cisplatin is one of the most frequently used chemotherapy drugs for diverse cancers.Although chemotherapeutic strategies have improved the prognosis and survival of cancer patients,development of cisplatin resistance has led to cancer recurrence.Curcumin,isolated from turmeric,has been used as an effective anti-cancer agent.However,the molecular mechanisms for curcumin-mediated cisplatin sensitivity of CRC have not been elucidated.展开更多
基金Supported by Fengtai District Commission of Health(Fengtai District Health System Science and Research Project NO.2023-81).
文摘Coronary artery calcification is common in eld-erly,diabetic,and dialysis-dependent patie-nts,poses a great challenge to interventional therapy and significantly increases the risk of complica-tions and poor prognosis.[1]Traditional rotational ath-erectomy and excimer laser coronary atherectomy are bo-th special treatment techniques for severely calcified le-sions,but they are difficult to use in clinical practice due to complicated operations.Intravascular lithotripsy(IVL)is a new way of treating calcified lesion.
文摘Objective:Colorectal cancer(CRC)is one of the most lethal and prevalent malignancies world-wide.Currently,surgery,radiotherapy and chemotherapy are clinically applied as common approaches for CRC patients.Cisplatin is one of the most frequently used chemotherapy drugs for diverse cancers.Although chemotherapeutic strategies have improved the prognosis and survival of cancer patients,development of cisplatin resistance has led to cancer recurrence.Curcumin,isolated from turmeric,has been used as an effective anti-cancer agent.However,the molecular mechanisms for curcumin-mediated cisplatin sensitivity of CRC have not been elucidated.
