Objective:To study the effect and prognosis and serological parameters between neuroendoscopy and microscope via order nasal sphenoid sinus approach of pituitary adenoma resection.Methods:120 patients with pituitary a...Objective:To study the effect and prognosis and serological parameters between neuroendoscopy and microscope via order nasal sphenoid sinus approach of pituitary adenoma resection.Methods:120 patients with pituitary adenoma were admitted in our hospital from January 2015 to January 2018, and were divided into two groups: observation group and control group, 60 cases in each group. The patients in the observation group were treated with pituitary tumor resection via the order nasal sphenoid sinus approach under neuroendoscopy, and the patients in the control group were treated with the pituitary adenoma resection under the microscope. The effects of operation on clinical efficacy, complications, prognosis, hormone level and visual function were compared between the two groups.Results: The total resection rate was significantly higher in the observation group than in the control group, and the recurrence rate, intraoperative bleeding, operative time and postoperative hospital stay were significantly lower than those in the control group, with statistically significant. The levels of ACTH, TSH and HGH in the two groups decreased significantly 2 weeks after operation, and the levels of hormone in the observation group were significantly lower than those in the control group 2 weeks after operation. The levels of NE, E, ATⅡ and R increased significantly in both groups, and the levels of stress indexes in the observation group were significantly lower than those in the control group. 2 weeks after operation, the MD, PSD, VFI of the two groups was significantly higher than that of the pre-operation group. The MD, VFI of the observation group was significantly higher than that of the control group, and the PSD was significantly lower than that of the control group. The main complications were cerebrospinal fluid leakage, urinary avalanche, intracranial hemorrhage and infection. The overall incidence of the patients in the observation group was significantly lower than that in the control group. Conclusion: The curative effect of pituitary adenoma resection via transsphenoidal approach by neuroendoscopy is significantly better than that of microsurgery. Neuroendoscopic surgery can significantly reduce intraoperative bleeding and stress response, thereby reducing the incidence of complications and contributing to the prognosis.展开更多
文摘Objective:To study the effect and prognosis and serological parameters between neuroendoscopy and microscope via order nasal sphenoid sinus approach of pituitary adenoma resection.Methods:120 patients with pituitary adenoma were admitted in our hospital from January 2015 to January 2018, and were divided into two groups: observation group and control group, 60 cases in each group. The patients in the observation group were treated with pituitary tumor resection via the order nasal sphenoid sinus approach under neuroendoscopy, and the patients in the control group were treated with the pituitary adenoma resection under the microscope. The effects of operation on clinical efficacy, complications, prognosis, hormone level and visual function were compared between the two groups.Results: The total resection rate was significantly higher in the observation group than in the control group, and the recurrence rate, intraoperative bleeding, operative time and postoperative hospital stay were significantly lower than those in the control group, with statistically significant. The levels of ACTH, TSH and HGH in the two groups decreased significantly 2 weeks after operation, and the levels of hormone in the observation group were significantly lower than those in the control group 2 weeks after operation. The levels of NE, E, ATⅡ and R increased significantly in both groups, and the levels of stress indexes in the observation group were significantly lower than those in the control group. 2 weeks after operation, the MD, PSD, VFI of the two groups was significantly higher than that of the pre-operation group. The MD, VFI of the observation group was significantly higher than that of the control group, and the PSD was significantly lower than that of the control group. The main complications were cerebrospinal fluid leakage, urinary avalanche, intracranial hemorrhage and infection. The overall incidence of the patients in the observation group was significantly lower than that in the control group. Conclusion: The curative effect of pituitary adenoma resection via transsphenoidal approach by neuroendoscopy is significantly better than that of microsurgery. Neuroendoscopic surgery can significantly reduce intraoperative bleeding and stress response, thereby reducing the incidence of complications and contributing to the prognosis.
