Yolk-shell nanostructures have recently attracted tremendous research interests in various areas because of their unique structural merits.Currently,there is an urgent need for developing porous shells with multifunct...Yolk-shell nanostructures have recently attracted tremendous research interests in various areas because of their unique structural merits.Currently,there is an urgent need for developing porous shells with multifunctional features to enhance their performance in various applications.Herein,advanced yolk-shell nanospheres have been facilely prepared by encapsulating silver nanoparticles with porous Janus polymer shells that consist of a hypercrosslinked polystyrene(xPS)outer layer and a tethered poly(acrylic acid)(PAA)brush lining.The xPS outer layer possesses well-developed porosity as mass diffusion pathways.More importantly,the tethered PAA brushes with customized carboxyl groups exhibit great affinity toward specific species(e.g.,cationic dyes),leading to their enrichment from the bulk solution into the interior cavity.The unusual combination of highly porous outer layers with customizable inbuilt polymer linings in the porous Janus shells endows them with great promise for synergistically catalytic degradation of cationic dyes.展开更多
背景:手术部位感染(SSI)是回肠造口还纳术后最常见的并发症之一。尽管一些皮肤闭合技术被提出以减少SSI发生率,但何种技术最优仍不明确。本研究比较了两种回肠造口还纳术后两种切口缝合技术(十字缝合与直线缝合)对SSI的影响。方法:2015...背景:手术部位感染(SSI)是回肠造口还纳术后最常见的并发症之一。尽管一些皮肤闭合技术被提出以减少SSI发生率,但何种技术最优仍不明确。本研究比较了两种回肠造口还纳术后两种切口缝合技术(十字缝合与直线缝合)对SSI的影响。方法:2015年1月至2017年12月间在中山大学附属第六医院进行回肠襻式造口的223例患者被纳入研究。根据造口还纳时的切口缝合方式,患者被分为直线缝合组(130例)和十字缝合组(103例)。比较两组患者临床病理特征,并分析SSI的危险因素。结果:两组患者均顺利完成手术。术后SSI发生率十字缝合组显著低于直线缝合组(2%vs 12%,P=0.007)。十字缝合组术后住院时间较直线缝合组显著缩短(8.1˘3.2 vs 10.8˘5.4天,P<0.001)。多因素分析证实,十字缝合是术后SSI的独立保护因素(OR=0.212,P=0.048)。结论:与直线缝合技术相比,十字缝合可显著降低SSI发生率并缩短术后住院时间。我们推荐将十字缝合用于回肠造口还纳手术的切口关闭。展开更多
基金This work was financially supported by the National Natural Science Foundation of China(Nos.51925308,U1601206,51672313,51702370,51872336)National Program for Support of Top-notch Young Professionals,Leading Scientific,Technical and Innovation Talents of Guangdong Special Support Program(No.2017TX04C248)+1 种基金Fundamental Research Funds for the Central Universities(Nos.18lgzd10,17lgpy83)the Science and Technology Program of Guangzhou(No.201704020059).
文摘Yolk-shell nanostructures have recently attracted tremendous research interests in various areas because of their unique structural merits.Currently,there is an urgent need for developing porous shells with multifunctional features to enhance their performance in various applications.Herein,advanced yolk-shell nanospheres have been facilely prepared by encapsulating silver nanoparticles with porous Janus polymer shells that consist of a hypercrosslinked polystyrene(xPS)outer layer and a tethered poly(acrylic acid)(PAA)brush lining.The xPS outer layer possesses well-developed porosity as mass diffusion pathways.More importantly,the tethered PAA brushes with customized carboxyl groups exhibit great affinity toward specific species(e.g.,cationic dyes),leading to their enrichment from the bulk solution into the interior cavity.The unusual combination of highly porous outer layers with customizable inbuilt polymer linings in the porous Janus shells endows them with great promise for synergistically catalytic degradation of cationic dyes.
基金supported by the Guangzhou Science and Technology Plan Project[No.201704020059 and 201803010074]National Key Clinical Discipline.
文摘背景:手术部位感染(SSI)是回肠造口还纳术后最常见的并发症之一。尽管一些皮肤闭合技术被提出以减少SSI发生率,但何种技术最优仍不明确。本研究比较了两种回肠造口还纳术后两种切口缝合技术(十字缝合与直线缝合)对SSI的影响。方法:2015年1月至2017年12月间在中山大学附属第六医院进行回肠襻式造口的223例患者被纳入研究。根据造口还纳时的切口缝合方式,患者被分为直线缝合组(130例)和十字缝合组(103例)。比较两组患者临床病理特征,并分析SSI的危险因素。结果:两组患者均顺利完成手术。术后SSI发生率十字缝合组显著低于直线缝合组(2%vs 12%,P=0.007)。十字缝合组术后住院时间较直线缝合组显著缩短(8.1˘3.2 vs 10.8˘5.4天,P<0.001)。多因素分析证实,十字缝合是术后SSI的独立保护因素(OR=0.212,P=0.048)。结论:与直线缝合技术相比,十字缝合可显著降低SSI发生率并缩短术后住院时间。我们推荐将十字缝合用于回肠造口还纳手术的切口关闭。
