Design of a NIM-based DAQ system

In order to satisfy the requirements of beam measurement in the heavy ion medical machine and other small nuclear physics experiments, we designed and built a nuclear instrumentation module-based data acquisition system. This is composed of a set of functional modules and a purpose-built bus. One of the modules operates as a master, collecting data from the other slave modules. It then sends the data to the back-end computer via Ethernet.In addition to the hardware, dedicated software has been designed and implemented. In this paper, we provide a detailed description of the architecture of the system, the data frame, and the software. The bus is the central part of the system. It can transmit data from the slave modules to the master at 33 MB/s. The frame used to transmit the data also ensures its integrity and monitors the hardware architecture. The client software is designed to process data in real time and store data on a hard disk for later analysis.

Upgraded control system designed for SECRAL

To improve the accuracy and usability of the superconducting electron cyclotron resonance ion source with advanced design in Lanzhou(SECRAL), an upgraded version of the control system was designed and tested. This paper details the architecture of the optimized control system and presents the results of its use in the long-term operation of the accelerator. The control system software, based on Visual C++, was developed following the model-view-controller architecture design pattern. The data acquisition system was based on a field-programmable gate array integrated circuit. In addition, control strategies were optimized for higher operational stability. The upgraded control system was tested with a U^(33+) ion beam at SECRAL, where it provided a data acquisition time of less than 1 ms. The fast reaction time and highprecision data processing during beam tuning verified the stability and maintainability of the control system.

Association between admission hemoglobin level and prognosis in patients with type 2 diabetes mellitus

BACKGROUND Anaemia is common in patients with chronic kidney disease(CKD)and is a major risk factor that contributes to mortality in such patients.Type 2 diabetes mellitus(T2DM)is one of the leading causes of CKD.The association between admission hemoglobin levels and renal damage in patients with T2DM remains unclear.AIM To evaluate the relationship between admission hemoglobin levels and prognosis in patients with T2DM.METHODS We performed a retrospective analysis of 265 consecutive patients presenting with T2DM between 2011 and 2015.The composite endpoint was end-stage renal disease or a 50%reduction in the estimated glomerular filtration rate.RESULTS In multivariable-adjusted Cox proportional hazards models(adjusting for demographic factors,traditional risk factors,lipids),the adjusted hazard ratios(HRs)for the highest and middle tertiles compared to the lowest tertile of hemoglobin were 0.82(95%CI:0.11-6.26,P=0.8457)and 0.28(95%CI:0.09-0.85,P=0.0246),respectively.However,after further adjustment for glycaemia control,hemoglobin was positively related to the risk of the composite endpoint(HR:1.05,95%CI:0.14-8.09,P=0.9602)when the highest tertile was compared to the lowest tertile of hemoglobin.We found a U-shaped relationship between hemoglobin levels and the composite endpoint.The curve tended to reach the lowest level at an optimal hemoglobin level.CONCLUSION Among patients with T2DM,a U-shaped relationship was observed between hemoglobin levels and renal damage.A lower admission hemoglobin level(hemoglobin<13.3 g/dL)is an independent predictor of renal damage.

Comparison between peroral traction-assisted ESD and traditional ESD treatment for early gastric cancer and precancerous lesions

Objective:To explore the differences in the effect of peroral traction-assisted endoscopic submucosal dissection (ESD) and traditional ESD for the treatment of early gastric cancer and precancerous lesions. Methods:112 patients with early gastric cancer and precancerous lesions treated in our hospital between May 2013 and May 2016 were collected and divided into control group and observation group according to the random number table (n=56). Observation group of patients received peroral traction-assisted ESD, and the control group of patients only received traditional ESD. The intraoperative dissected lesion diameter, mean operation time and intraoperative blood loss of two groups of patients were recorded, enzyme-linked immunosorbent assay was used to detect serum inflammatory factor levels, and RIA was used to detect serum stress hormone levels. Results:Dissected lesion diameter of observation group was greater than that of control group (P<0.05) while mean operation time and intraoperative blood loss were less than those of control group (P<0.05);1 d after operation, serum inflammatory factors interleukin-6 (IL-6), interleukin-8 (IL-8), interleukin-12 (IL-12) and tumor necrosis factor-α(TNF-α) levels of observation group were lower than those of control group (P<0.05), and serum stress hormones cortisol (Cor),β-endorphin (β-EP), epinephrine (E), norepinephrine (NE) and angiotensin II (ATII) levels were lower than those of control group (P<0.05). Conclusions:Peroral traction-assisted ESD can effectively increase the lesion dissection effect and reduce the postoperative inflammatory response and stress response in patients with early gastric cancer and precancerous lesions.