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MRI参数与巨噬细胞炎性蛋白3α和鼻咽癌病理特征的关系 被引量:6
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作者 刘文洪 罗光华 赵衡 《中国现代医学杂志》 CAS 2018年第27期116-119,共4页
目的通过MRI增强扫描参数与检测血清巨噬细胞炎性蛋白3α(MIP-3α)在鼻咽癌患者中的表达情况,探讨其在鼻咽癌诊断、与临床病理特征关系以及疗效评价中的作用。方法应用定量ELISA检测120例初治无远处转移的鼻咽癌患者血清MIP-3α的表达和... 目的通过MRI增强扫描参数与检测血清巨噬细胞炎性蛋白3α(MIP-3α)在鼻咽癌患者中的表达情况,探讨其在鼻咽癌诊断、与临床病理特征关系以及疗效评价中的作用。方法应用定量ELISA检测120例初治无远处转移的鼻咽癌患者血清MIP-3α的表达和MRI增强扫描参数情况。结果 120例鼻咽癌患者经过治疗后均达到完全缓解或部分缓解,鼻咽癌患者活检部位的MRI动态参数与血清MIP-3α表达呈正相关(P <0.05);鼻咽癌患者血清MIP-3α水平高于健康对照者。不同T分期、N分期及临床分期患者的曲线最大上升斜率比较,差异有统计学意义(P <0.05);MIP-3α与鼻咽癌临床分期相关,MIP-3α还与T分期有关(P<0.05)。治疗后完全缓解患者的血清MIP-3α降至健康对照者水平,部分缓解患者仍高于健康对照者水平;鼻咽癌患者活检部位的MRI动态参数与血清MIP-3α表达呈正相关。结论血清MIP-3α水平作为辅助诊断鼻咽癌的指标有一定的临床意义,其与磁共振增强扫描参数与检测有助于判断鼻咽癌分期和治疗后的近期疗效。 展开更多
关键词 磁共振增强扫描参数 血清巨噬细胞炎性蛋白3α 鼻咽癌 诊断
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Prevalence of post-traumatic stress disorder after earthquakes among the elderly in China: A meta-analysis 被引量:1
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作者 Yong Liang Hong Zeng +2 位作者 Yu-geng liu Ai-min Xu wen-hong liu 《World Journal of Emergency Medicine》 SCIE CAS CSCD 2021年第2期137-142,共6页
BACKGROUND: The study aims to investigate the occurrence of post-traumatic stress disorder(PTSD) after earthquakes among the elderly. METHODS: Data from cross-sectional studies focusing on the prevalence of PTSD after... BACKGROUND: The study aims to investigate the occurrence of post-traumatic stress disorder(PTSD) after earthquakes among the elderly. METHODS: Data from cross-sectional studies focusing on the prevalence of PTSD after earthquakes among the elderly were collected from Pub Med, EMBASE, Cochrane Library, and China National Knowledge Infrastructure in December 2019. The search terms included post-traumatic stress disorder, earthquake, and elderly. This study used Review Manager 5.0 to evaluate the impact of the results. In addition, forest plots, sensitivity analysis, and bias analysis were carried out on the included articles. The combined estimate of the risk ratio and the standard deviation of the 95% confidence interval(95% CI) were measurements of the size of the effect.RESULTS: There were 4,834 patients included from 10 eligible studies. The sample sizes of PTSD group and non-PTSD group were 1,277 and 3,557, respectively. The meta-analysis showed that the overall occurrence of PTSD after earthquakes among the elderly was 0.25;the occurrence in females was higher than that in males, and the occurrence in the same province indicated little difference(Wenchuan city 0.25 and Ya'an city 0.24).CONCLUSIONS: After earthquakes, the occurrence of PTSD is higher among the elderly than among other age groups, and higher among the females than among the males, while there is little difference among different areas within the same province. This indicated that prioritized specific psychological interventions should be provided to the aged and the females. 展开更多
关键词 Post-traumatic stress disorder The elderly EARTHQUAKE
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