Yolk-shell nanostructures have recently attracted tremendous research interests in various areas because of their unique structural merits.Currently,there is an urgent need for developing porous shells with multifunct...Yolk-shell nanostructures have recently attracted tremendous research interests in various areas because of their unique structural merits.Currently,there is an urgent need for developing porous shells with multifunctional features to enhance their performance in various applications.Herein,advanced yolk-shell nanospheres have been facilely prepared by encapsulating silver nanoparticles with porous Janus polymer shells that consist of a hypercrosslinked polystyrene(xPS)outer layer and a tethered poly(acrylic acid)(PAA)brush lining.The xPS outer layer possesses well-developed porosity as mass diffusion pathways.More importantly,the tethered PAA brushes with customized carboxyl groups exhibit great affinity toward specific species(e.g.,cationic dyes),leading to their enrichment from the bulk solution into the interior cavity.The unusual combination of highly porous outer layers with customizable inbuilt polymer linings in the porous Janus shells endows them with great promise for synergistically catalytic degradation of cationic dyes.展开更多
Background:Surgical-site infection(SSI)was one of the most common post-operative morbidities of ileostomy reversal.Although several skin-closure procedures had been developed to reduce the rate of SSI,the optimal proc...Background:Surgical-site infection(SSI)was one of the most common post-operative morbidities of ileostomy reversal.Although several skin-closure procedures had been developed to reduce the rate of SSI,the optimal procedure remains unclear.In this study,we compared the effect of two surgical techniques for wound closure following ileostomy reversal:gunsight suture(GS)and linear suture(LS).Methods:A total of 233 patients who underwent loop ileostomy at the Sixth Affiliated Hospital of Sun Yat-sen University between January 2015 and December 2017 were enrolled into our study.These patients were divided into two groups:the LS group and the GS group.We compared the clinical characteristics between the two groups and analyzed the data using IBM SPSS to identify risk factors for SSI.Results:Both groups successfully underwent surgery.The rate of SSI was significantly lower in the GS group(n=2,0.02%)than in the LS group(n=16,12.00%,P=0.007).The length of hospital stay after the operation in the GS group was significantly shorter than that in the LS group(8.163.2 vs 10.865.4 days,P<0.001).Multivariate analysis showed that GS was an independent protective risk factor for SSI(odds ratio=0.212,P=0.048).Conclusions:Compared with the LS technique,the GS technique can significantly decrease the rate of SSI and shorten the length of hospital stay after surgery.The GS technique may be recommended for wound closure following ileostomy reversal.展开更多
基金This work was financially supported by the National Natural Science Foundation of China(Nos.51925308,U1601206,51672313,51702370,51872336)National Program for Support of Top-notch Young Professionals,Leading Scientific,Technical and Innovation Talents of Guangdong Special Support Program(No.2017TX04C248)+1 种基金Fundamental Research Funds for the Central Universities(Nos.18lgzd10,17lgpy83)the Science and Technology Program of Guangzhou(No.201704020059).
文摘Yolk-shell nanostructures have recently attracted tremendous research interests in various areas because of their unique structural merits.Currently,there is an urgent need for developing porous shells with multifunctional features to enhance their performance in various applications.Herein,advanced yolk-shell nanospheres have been facilely prepared by encapsulating silver nanoparticles with porous Janus polymer shells that consist of a hypercrosslinked polystyrene(xPS)outer layer and a tethered poly(acrylic acid)(PAA)brush lining.The xPS outer layer possesses well-developed porosity as mass diffusion pathways.More importantly,the tethered PAA brushes with customized carboxyl groups exhibit great affinity toward specific species(e.g.,cationic dyes),leading to their enrichment from the bulk solution into the interior cavity.The unusual combination of highly porous outer layers with customizable inbuilt polymer linings in the porous Janus shells endows them with great promise for synergistically catalytic degradation of cationic dyes.
基金supported by the Guangzhou Science and Technology Plan Project[No.201704020059 and 201803010074]National Key Clinical Discipline.
文摘Background:Surgical-site infection(SSI)was one of the most common post-operative morbidities of ileostomy reversal.Although several skin-closure procedures had been developed to reduce the rate of SSI,the optimal procedure remains unclear.In this study,we compared the effect of two surgical techniques for wound closure following ileostomy reversal:gunsight suture(GS)and linear suture(LS).Methods:A total of 233 patients who underwent loop ileostomy at the Sixth Affiliated Hospital of Sun Yat-sen University between January 2015 and December 2017 were enrolled into our study.These patients were divided into two groups:the LS group and the GS group.We compared the clinical characteristics between the two groups and analyzed the data using IBM SPSS to identify risk factors for SSI.Results:Both groups successfully underwent surgery.The rate of SSI was significantly lower in the GS group(n=2,0.02%)than in the LS group(n=16,12.00%,P=0.007).The length of hospital stay after the operation in the GS group was significantly shorter than that in the LS group(8.163.2 vs 10.865.4 days,P<0.001).Multivariate analysis showed that GS was an independent protective risk factor for SSI(odds ratio=0.212,P=0.048).Conclusions:Compared with the LS technique,the GS technique can significantly decrease the rate of SSI and shorten the length of hospital stay after surgery.The GS technique may be recommended for wound closure following ileostomy reversal.
