Summary What is already known about this topic?Although ticks and tick-borne diseases are prevalent throughout China,there remains a knowledge gap regarding their biology and potential risk of distribution to human an...Summary What is already known about this topic?Although ticks and tick-borne diseases are prevalent throughout China,there remains a knowledge gap regarding their biology and potential risk of distribution to human and animal populations on Chongming Island.The island,being China’s third largest and a crucial component in the ecological preservation of the Yangtze Delta region,has yet to be comprehensively studied in this context.展开更多
A bioinspired acid-triggered hemiacetalization/dehydration/[3 + 3]-type cycloaddition cascade process was disclosed, diastereoselectively furnishing furo[2,3-b]chromene skeleton under mild conditions. The viability of...A bioinspired acid-triggered hemiacetalization/dehydration/[3 + 3]-type cycloaddition cascade process was disclosed, diastereoselectively furnishing furo[2,3-b]chromene skeleton under mild conditions. The viability of this approach was demonstrated by syntheses of a series of furo[2,3-b]chromene and pyrano[2,3-b]chromene derivatives. The successful total syntheses of two lignan-phloroglucinol hybrids,hyperaspidinols A and B, exemplified the synthetic utility of our biomimetic methodology.展开更多
基金Supported by the financial backing of the Science and Technology Innovation Project Fund from the School of Global Health,Shanghai Jiao Tong University School of Medicine(SGHKJCX2021-05,SGHKJCX2021-04)the International Joint Laboratory on Tropical Diseases Control in Greater Mekong Subregion(21410750200).
文摘Summary What is already known about this topic?Although ticks and tick-borne diseases are prevalent throughout China,there remains a knowledge gap regarding their biology and potential risk of distribution to human and animal populations on Chongming Island.The island,being China’s third largest and a crucial component in the ecological preservation of the Yangtze Delta region,has yet to be comprehensively studied in this context.
基金supported financially by the National Natural Science Foundation of China (Nos.81773602,21901049 and 21801032)Natural Science Foundation of Guangdong Province (No.2019A1515011694)+2 种基金Guangdong Special Support Program (No.2017TQ04R599)Youth Innovation Promotion Association of CAS (No.2020342)Guangxi Natural Science Foundation (Nos.2018GXNSFBA050015 and AD19245004)。
文摘A bioinspired acid-triggered hemiacetalization/dehydration/[3 + 3]-type cycloaddition cascade process was disclosed, diastereoselectively furnishing furo[2,3-b]chromene skeleton under mild conditions. The viability of this approach was demonstrated by syntheses of a series of furo[2,3-b]chromene and pyrano[2,3-b]chromene derivatives. The successful total syntheses of two lignan-phloroglucinol hybrids,hyperaspidinols A and B, exemplified the synthetic utility of our biomimetic methodology.
