Background and Objective: Giant cavernous carotid artery aneurysms (CCAAs) often produce a variety of neurological deficits, primarily those related to ophthalmoplegia/paresis and headache. This study was designed to ...Background and Objective: Giant cavernous carotid artery aneurysms (CCAAs) often produce a variety of neurological deficits, primarily those related to ophthalmoplegia/paresis and headache. This study was designed to evaluate the resolution of symptoms after parent artery occlusion (PAO) treatment for giant CCAAs. Methods: We retrospectively reviewed a series of 17 consecutive giant CCAAs treated with PAO treatment. All patients were evaluated by balloon occlusion test (BOT) before treatment. Patients who could tolerate BOT were treated by PAO. The following outcomes were analyzed: angiographic assessment, evolution of symptoms and outcome at clinical follow-up using modified Rankin Scale (mRS). Results: A total number of 17 giant CCAAs were treated by PAO. The initial post-procedure and follow-up angiogram revealed complete occlusion in all patients, no new lesion was detected. Periprocedural infarcts occurred in 1 patient (5.9%). Procedure-related mortality and morbidity were 0% and 5.9%, respectively. At mean 31.8 months clinical follow-up, symptoms had disappeared in 7 (41.2%) of the patients, partially improved in 5 (29.4%), remained unchanged in 4 (23.5%) and worsened in 1 (5.9%) of cases. Sixteen (94.1%) patients presented a good clinical outcome (mRS 0 - 1). Conclusion: Most patients in our series improved or remained stable after PAO. The results of this study indicate that PAO can improve the outcome of those symptomatic giant CCAAs if BOT can be tolerated.展开更多
Digital soil mapping (DSM) aims to produce detailed maps of soil properties or soil classes to improve agricultural management and soil quality assessment. Optimized sampling design can reduce the substantial costs an...Digital soil mapping (DSM) aims to produce detailed maps of soil properties or soil classes to improve agricultural management and soil quality assessment. Optimized sampling design can reduce the substantial costs and efforts associated with sampling, profile description, and laboratory analysis. The purpose of this study was to compare common sampling designs for DSM, including grid sampling (GS), grid random sampling (GRS), stratified random sampling (StRS), and conditioned Latin hypercube sampling (cLHS). In an agricultural field (11 ha) in Quebec, Canada, a total of unique 118 locations were selected using each of the four sampling designs (45 locations each), and additional 30 sample locations were selected as an independent testing dataset (evaluation dataset). Soil visible near-infrared (Vis-NIR) spectra were collected in situ at the 148 locations (1 m depth), and soil cores were collected from a subset of 32 locations and subdivided at 10-cm depth intervals, totaling 251 samples. The Cubist model was used to elucidate the relationship between Vis-NIR spectra and soil properties (soil organic matter (SOM) and clay), which was then used to predict the soil properties at all 148 sample locations. Digital maps of soil properties at multiple depths for the entire field (148 sample locations) were prepared using a quantile random forest model to obtain complete model maps (CM-maps). Soil properties were also mapped using the samples from each of the 45 locations for each sampling design to obtain sampling design maps (SD-maps). The SD-maps were evaluated using the independent testing dataset (30 sample locations), and the spatial distribution and model uncertainty of each SD-map were compared with those of the corresponding CM-map. The spatial and feature space coverage were compared across the four sampling designs. The results showed that GS resulted in the most even spatial coverage, cLHS resulted in the best coverage of the feature space, and GS and cLHS resulted in similar prediction accuracies and spatial distributions of soil properties. The SOM content was underestimated using GRS, with large errors at 0–50 cm depth, due to some values not being captured by this sampling design, whereas larger errors for the deeper soil layers were produced using StRS. Predictions of SOM and clay contents had higher accuracy for topsoil (0–30 cm) than for deep subsoil (60–100 cm). It was concluded that the soil sampling designs with either good spatial coverage or feature space coverage can provide good accuracy in 3D DSM, but their performances may be different for different soil properties.展开更多
文摘Background and Objective: Giant cavernous carotid artery aneurysms (CCAAs) often produce a variety of neurological deficits, primarily those related to ophthalmoplegia/paresis and headache. This study was designed to evaluate the resolution of symptoms after parent artery occlusion (PAO) treatment for giant CCAAs. Methods: We retrospectively reviewed a series of 17 consecutive giant CCAAs treated with PAO treatment. All patients were evaluated by balloon occlusion test (BOT) before treatment. Patients who could tolerate BOT were treated by PAO. The following outcomes were analyzed: angiographic assessment, evolution of symptoms and outcome at clinical follow-up using modified Rankin Scale (mRS). Results: A total number of 17 giant CCAAs were treated by PAO. The initial post-procedure and follow-up angiogram revealed complete occlusion in all patients, no new lesion was detected. Periprocedural infarcts occurred in 1 patient (5.9%). Procedure-related mortality and morbidity were 0% and 5.9%, respectively. At mean 31.8 months clinical follow-up, symptoms had disappeared in 7 (41.2%) of the patients, partially improved in 5 (29.4%), remained unchanged in 4 (23.5%) and worsened in 1 (5.9%) of cases. Sixteen (94.1%) patients presented a good clinical outcome (mRS 0 - 1). Conclusion: Most patients in our series improved or remained stable after PAO. The results of this study indicate that PAO can improve the outcome of those symptomatic giant CCAAs if BOT can be tolerated.
基金the National Science and Engineering Research Council of Canada(No.RGPIN-2014-04100)for funding this project.
文摘Digital soil mapping (DSM) aims to produce detailed maps of soil properties or soil classes to improve agricultural management and soil quality assessment. Optimized sampling design can reduce the substantial costs and efforts associated with sampling, profile description, and laboratory analysis. The purpose of this study was to compare common sampling designs for DSM, including grid sampling (GS), grid random sampling (GRS), stratified random sampling (StRS), and conditioned Latin hypercube sampling (cLHS). In an agricultural field (11 ha) in Quebec, Canada, a total of unique 118 locations were selected using each of the four sampling designs (45 locations each), and additional 30 sample locations were selected as an independent testing dataset (evaluation dataset). Soil visible near-infrared (Vis-NIR) spectra were collected in situ at the 148 locations (1 m depth), and soil cores were collected from a subset of 32 locations and subdivided at 10-cm depth intervals, totaling 251 samples. The Cubist model was used to elucidate the relationship between Vis-NIR spectra and soil properties (soil organic matter (SOM) and clay), which was then used to predict the soil properties at all 148 sample locations. Digital maps of soil properties at multiple depths for the entire field (148 sample locations) were prepared using a quantile random forest model to obtain complete model maps (CM-maps). Soil properties were also mapped using the samples from each of the 45 locations for each sampling design to obtain sampling design maps (SD-maps). The SD-maps were evaluated using the independent testing dataset (30 sample locations), and the spatial distribution and model uncertainty of each SD-map were compared with those of the corresponding CM-map. The spatial and feature space coverage were compared across the four sampling designs. The results showed that GS resulted in the most even spatial coverage, cLHS resulted in the best coverage of the feature space, and GS and cLHS resulted in similar prediction accuracies and spatial distributions of soil properties. The SOM content was underestimated using GRS, with large errors at 0–50 cm depth, due to some values not being captured by this sampling design, whereas larger errors for the deeper soil layers were produced using StRS. Predictions of SOM and clay contents had higher accuracy for topsoil (0–30 cm) than for deep subsoil (60–100 cm). It was concluded that the soil sampling designs with either good spatial coverage or feature space coverage can provide good accuracy in 3D DSM, but their performances may be different for different soil properties.