The sluggish kinetics of both hydrogen evolution reaction(HER)and oxygen evolution reaction(OER)generate the large overpotential in water electrolysis and thus high-cost hydrogen production.Here,multidimensional nanop...The sluggish kinetics of both hydrogen evolution reaction(HER)and oxygen evolution reaction(OER)generate the large overpotential in water electrolysis and thus high-cost hydrogen production.Here,multidimensional nanoporous interpenetrating-phase FeNiZn alloy and FeNi_(3)intermetallic heterostructure is in situ constructed on NiFe foam(FeNiZn/FeNi_(3)@NiFe)by dealloying protocol.Coupling with the eminent synergism among specific constituents and the highly efficient mass transport from integrated porous backbone,FeNiZn/FeNi_(3)@NiFe depicts exceptional bifunctional activities for water splitting with extremely low overpotentials toward OER and HER(η_(1000)=367/245 mV)as well as the robust durability during the 400 h testing in alkaline solution.The as-built water electrolyzer with FeNiZn/FeNi_(3)@NiFe as both anode and cathode exhibits record-high performances for sustainable hydrogen output in terms of much lower cell voltage of 1.759 and 1.919 V to deliver the current density of 500 and 1000 mA cm^(-2)as well long working lives.Density functional theory calculations disclose that the interface interaction between FeNiZn alloy and FeNi_(3)intermetallic generates the modulated electron structure state and optimized intermediate chemisorption,thus diminishing the energy barriers for hydrogen production in water splitting.With the merits of fine performances,scalable fabrication,and low cost,FeNiZn/FeNi_(3)@NiFe holds prospective application potential as the bifunctional electrocatalyst for water splitting.展开更多
The grey relational analysis( GRA) was used to evaluate the 10 sugarcane lines by 13 main agronomic characters. The result showed that the grey correlation degree of self-cultivated lines GNY08- 320(0. 7502),GNY08- 33...The grey relational analysis( GRA) was used to evaluate the 10 sugarcane lines by 13 main agronomic characters. The result showed that the grey correlation degree of self-cultivated lines GNY08- 320(0. 7502),GNY08- 336(0. 7409),GNY08- 186(0. 7369),and GNY08- 225(0. 7277) were higher than ROC22(CK),so the 4 lines can be further tested,and the others were worse than CK that should be further observed or eliminated.展开更多
Li-CO_(2)batteries are among the most intriguing techniques for balancing the carbon cycle,but are challenged by the annoyed thermodynamic barrier of the Li_(2)CO_(3)decomposition reaction.Herein,we demonstrate the el...Li-CO_(2)batteries are among the most intriguing techniques for balancing the carbon cycle,but are challenged by the annoyed thermodynamic barrier of the Li_(2)CO_(3)decomposition reaction.Herein,we demonstrate the electrocatalytic performances of two-dimensional(2D)CoAl-layer double hydroxide(LDH)nanosheets can be significantly improved by trans-dimensional crosslinking with three-dimensional(3D)multilevel nanoporous(MP)-RuCoAl alloy(MP-RuCoAl alloy⊥CoAl-LDH).The MP-RuCoAl alloy⊥CoAl-LDH with multiscale pore channels and abundant nano-heterointerface is directly prepared by controllable etching Al from a Ru-Co-Al master alloy along with simultaneous partial oxidization of Al and Co atoms.The MP-RuCoAl is composed of various intermetallic compounds and Ru with abundant grain boundaries,and forms numerous heterointerface with 2D CoAl-LDH nanosheets.The multiscale porous metallic network benefits mass and electron transportation as well as discharge product storage and enables a rich multiphase reaction interface.In situ differential electrochemical mass spectrometry shows that the mass-to-charge ratio in the charging process is~0.733 which is consistent with the theoretical value of 3/4,stating that the reversible co-decomposition of Li_(2)CO_(3)and C can be achieved with the MP-RuCoAl alloy⊥CoAl-LDH.The Ketjen black(KB)/MP-RuCoAl⊥CoAl-LDH battery demonstrates a high cyclability for over 2270 h(227 cycles)with a lower voltage gap stabilized at~1.3 V at 200 mA·g^(−1).Our findings here provide useful guidelines for developing high efficiency transition metal based electrocatalysts by coupling with conductive porous substrate for impelling the development of practical Li-CO_(2)battery systems.展开更多
The global coronavirus disease 2019(COVID-19)pandemic caused by severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)has caused severe morbidity and mortality in humans.It is urgent to understand the function of...The global coronavirus disease 2019(COVID-19)pandemic caused by severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)has caused severe morbidity and mortality in humans.It is urgent to understand the function of viral genes.However,the function of open reading frame 10(ORF10),which is uniquely expressed by SARS-CoV-2,remains unclear.In this study,we showed that overexpression of ORF10 markedly suppressed the expression of type I interferon(IFN-I)genes and IFN-stimulated genes.Then,mitochondrial antiviral signaling protein(MAVS)was identified as the target via which ORF10 suppresses the IFN-I signaling pathway,and MAVS was found to be degraded through the ORF10-induced autophagy pathway.Furthermore,overexpression of ORF10 promoted the accumulation of LC3 in mitochondria and induced mitophagy.Mechanistically,ORF10 was translocated to mitochondria by interacting with the mitophagy receptor Nip3-like protein X(NIX)and induced mitophagy through its interaction with both NIX and LC3B.Moreover,knockdown of NIX expression blocked mitophagy activation,MAVS degradation,and IFN-I signaling pathway inhibition by ORF10.Consistent with our observations,in the context of SARS-CoV-2 infection,ORF10 inhibited MAVS expression and facilitated viral replication.In brief,our results reveal a novel mechanism by which SARS-CoV-2 inhibits the innate immune response;that is,ORF10 induces mitophagy-mediated MAVS degradation by binding to NIX.展开更多
Li–CO_(2) batteries,which integrate CO_(2) utilization and electrochemical energy storage,offer the prospect of utilizing a greenhouse gas and providing an alternative to the well-established lithium-ion batteries.Ho...Li–CO_(2) batteries,which integrate CO_(2) utilization and electrochemical energy storage,offer the prospect of utilizing a greenhouse gas and providing an alternative to the well-established lithium-ion batteries.However,they still suffer from rather limited reversibility,low energy efficiency,and sluggish CO_(2) redox reaction kinetics.To address these key issues,a nanoporous Ni_(3)Al intermetallic/Ni heterojunction(NP–Ni_(3) Al/Ni)is purposely engi-neered here via an alloying–etching protocol,whereby the unique interactions between Al and Ni in Ni_(3)Al endow NP-Ni_(3)Al/Ni with optimum reactant/product adsorption and thus unique catalytic performance for the CO_(2) redox reaction.Furthermore,the nanoporous spongy structure benefits mass transport as well as discharge product storage and enables a rich multiphase reaction interface.In situ Raman studies and theoretical simulations reveal that both CO_(2) reduction and the co-decomposition of Li_(2)CO_(3) and C are distinctly promoted by NP-Ni_(3)Al/Ni,thereby greatly improving catalytic activity and stability.NP-Ni_(3)Al/Ni offers promising application potential in Li–CO_(2) batteries,with its scalable fabrication,low production cost,and superior catalytic performance.展开更多
基金supported by National Science Foundation of China(52201254)Shandong Province(ZR2020MB090,ZR2020QE012)the project of“20 Items of University”of Jinan(202228046)。
文摘The sluggish kinetics of both hydrogen evolution reaction(HER)and oxygen evolution reaction(OER)generate the large overpotential in water electrolysis and thus high-cost hydrogen production.Here,multidimensional nanoporous interpenetrating-phase FeNiZn alloy and FeNi_(3)intermetallic heterostructure is in situ constructed on NiFe foam(FeNiZn/FeNi_(3)@NiFe)by dealloying protocol.Coupling with the eminent synergism among specific constituents and the highly efficient mass transport from integrated porous backbone,FeNiZn/FeNi_(3)@NiFe depicts exceptional bifunctional activities for water splitting with extremely low overpotentials toward OER and HER(η_(1000)=367/245 mV)as well as the robust durability during the 400 h testing in alkaline solution.The as-built water electrolyzer with FeNiZn/FeNi_(3)@NiFe as both anode and cathode exhibits record-high performances for sustainable hydrogen output in terms of much lower cell voltage of 1.759 and 1.919 V to deliver the current density of 500 and 1000 mA cm^(-2)as well long working lives.Density functional theory calculations disclose that the interface interaction between FeNiZn alloy and FeNi_(3)intermetallic generates the modulated electron structure state and optimized intermediate chemisorption,thus diminishing the energy barriers for hydrogen production in water splitting.With the merits of fine performances,scalable fabrication,and low cost,FeNiZn/FeNi_(3)@NiFe holds prospective application potential as the bifunctional electrocatalyst for water splitting.
基金Supported by Key Scientific and Technological Planning Project of Guangxi(Gui Ke Neng 1347013-7)Ability Construction Project for Innovation Plan of Chongzuo City of Guangxi(2012cxjhB001)Public Welfare Foundation Project of Guangxi Department of Finance(NYRKS201205 & XJYJS201309)
文摘The grey relational analysis( GRA) was used to evaluate the 10 sugarcane lines by 13 main agronomic characters. The result showed that the grey correlation degree of self-cultivated lines GNY08- 320(0. 7502),GNY08- 336(0. 7409),GNY08- 186(0. 7369),and GNY08- 225(0. 7277) were higher than ROC22(CK),so the 4 lines can be further tested,and the others were worse than CK that should be further observed or eliminated.
基金the National Natural Science Foundation of China(No.52201254)the Natural Science Foundation of Shandong Province(Nos.ZR2020QE012,ZR2020MB090,ZR2023ME155,and ZR2023ME085)+1 种基金the project of“20 Items of University”of Jinan(No.202228046)the Taishan Scholar Project of Shandong Province(No.tsqn202306226).
文摘Li-CO_(2)batteries are among the most intriguing techniques for balancing the carbon cycle,but are challenged by the annoyed thermodynamic barrier of the Li_(2)CO_(3)decomposition reaction.Herein,we demonstrate the electrocatalytic performances of two-dimensional(2D)CoAl-layer double hydroxide(LDH)nanosheets can be significantly improved by trans-dimensional crosslinking with three-dimensional(3D)multilevel nanoporous(MP)-RuCoAl alloy(MP-RuCoAl alloy⊥CoAl-LDH).The MP-RuCoAl alloy⊥CoAl-LDH with multiscale pore channels and abundant nano-heterointerface is directly prepared by controllable etching Al from a Ru-Co-Al master alloy along with simultaneous partial oxidization of Al and Co atoms.The MP-RuCoAl is composed of various intermetallic compounds and Ru with abundant grain boundaries,and forms numerous heterointerface with 2D CoAl-LDH nanosheets.The multiscale porous metallic network benefits mass and electron transportation as well as discharge product storage and enables a rich multiphase reaction interface.In situ differential electrochemical mass spectrometry shows that the mass-to-charge ratio in the charging process is~0.733 which is consistent with the theoretical value of 3/4,stating that the reversible co-decomposition of Li_(2)CO_(3)and C can be achieved with the MP-RuCoAl alloy⊥CoAl-LDH.The Ketjen black(KB)/MP-RuCoAl⊥CoAl-LDH battery demonstrates a high cyclability for over 2270 h(227 cycles)with a lower voltage gap stabilized at~1.3 V at 200 mA·g^(−1).Our findings here provide useful guidelines for developing high efficiency transition metal based electrocatalysts by coupling with conductive porous substrate for impelling the development of practical Li-CO_(2)battery systems.
基金This work was partially supported by grants from the National Natural Science Fund of China(31872490,31972665,and 32072834)Taishan Scholar and Distinguished Experts(to H.H.).
文摘The global coronavirus disease 2019(COVID-19)pandemic caused by severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)has caused severe morbidity and mortality in humans.It is urgent to understand the function of viral genes.However,the function of open reading frame 10(ORF10),which is uniquely expressed by SARS-CoV-2,remains unclear.In this study,we showed that overexpression of ORF10 markedly suppressed the expression of type I interferon(IFN-I)genes and IFN-stimulated genes.Then,mitochondrial antiviral signaling protein(MAVS)was identified as the target via which ORF10 suppresses the IFN-I signaling pathway,and MAVS was found to be degraded through the ORF10-induced autophagy pathway.Furthermore,overexpression of ORF10 promoted the accumulation of LC3 in mitochondria and induced mitophagy.Mechanistically,ORF10 was translocated to mitochondria by interacting with the mitophagy receptor Nip3-like protein X(NIX)and induced mitophagy through its interaction with both NIX and LC3B.Moreover,knockdown of NIX expression blocked mitophagy activation,MAVS degradation,and IFN-I signaling pathway inhibition by ORF10.Consistent with our observations,in the context of SARS-CoV-2 infection,ORF10 inhibited MAVS expression and facilitated viral replication.In brief,our results reveal a novel mechanism by which SARS-CoV-2 inhibits the innate immune response;that is,ORF10 induces mitophagy-mediated MAVS degradation by binding to NIX.
基金This work was financially supported by the National Natural Science Foundation of China(52201254)the Natural Science Foundation of Shandong Province(ZR2020QE012,ZR2020MB090)+2 种基金the project of“20 Items of University”of Jinan(202228046)the Taishan Scholar Project of Shandong ProvinceJ.W.acknowledges the support of the Singapore Ministry of Education,for research conducted at the National University of Singapore(Tier 1,A-8000186-01-00).
文摘Li–CO_(2) batteries,which integrate CO_(2) utilization and electrochemical energy storage,offer the prospect of utilizing a greenhouse gas and providing an alternative to the well-established lithium-ion batteries.However,they still suffer from rather limited reversibility,low energy efficiency,and sluggish CO_(2) redox reaction kinetics.To address these key issues,a nanoporous Ni_(3)Al intermetallic/Ni heterojunction(NP–Ni_(3) Al/Ni)is purposely engi-neered here via an alloying–etching protocol,whereby the unique interactions between Al and Ni in Ni_(3)Al endow NP-Ni_(3)Al/Ni with optimum reactant/product adsorption and thus unique catalytic performance for the CO_(2) redox reaction.Furthermore,the nanoporous spongy structure benefits mass transport as well as discharge product storage and enables a rich multiphase reaction interface.In situ Raman studies and theoretical simulations reveal that both CO_(2) reduction and the co-decomposition of Li_(2)CO_(3) and C are distinctly promoted by NP-Ni_(3)Al/Ni,thereby greatly improving catalytic activity and stability.NP-Ni_(3)Al/Ni offers promising application potential in Li–CO_(2) batteries,with its scalable fabrication,low production cost,and superior catalytic performance.
