Female breast cancer(BCa)has overtaken lung cancer as the most diagnosed cancer worldwide.1 The overall survival for BCa patients without metastasis for five years is over 80%.2 However,relapse and metastasis remain t...Female breast cancer(BCa)has overtaken lung cancer as the most diagnosed cancer worldwide.1 The overall survival for BCa patients without metastasis for five years is over 80%.2 However,relapse and metastasis remain the primary challenge for BCa.In various carcinomas,Holliday junction recognition protein(HJURP)has shown up-regulated patterns and belongs to the CENP-A pre-nucleosomal complex.3-°HJURP's expression pattern,roles,and prognosis remain largely unknown in BCa.展开更多
基金funded by the National Natural Science Youth Fund of China (No.82103626)the Nanjing Gaochun People's Hospital Institute-Level High-Quality Scientific Research Projects (China) (No.GYK-2022-002).
文摘Female breast cancer(BCa)has overtaken lung cancer as the most diagnosed cancer worldwide.1 The overall survival for BCa patients without metastasis for five years is over 80%.2 However,relapse and metastasis remain the primary challenge for BCa.In various carcinomas,Holliday junction recognition protein(HJURP)has shown up-regulated patterns and belongs to the CENP-A pre-nucleosomal complex.3-°HJURP's expression pattern,roles,and prognosis remain largely unknown in BCa.