Consumer acceptability and sensory profiling of sesame oils obtained from different processes

This study aimed to investigate the effect of oil processing technologies on the sensory qualities of sesame oils and to identify drivers of liking.Using a check-all-that-apply(CATA)question and a hedonic scale,150 consumers evaluated the acceptability and sensory characteristics of 5 sesame oil samples including an aqueous extracted oil(S1),a cold-pressed oil(S2),two batches of screw-pressed oils(S3 and S5)and one crude sesame oil(S4).Solid-phase microextraction-gas chromatography-olfactometry-mass spectrometry(SPME-GC-O-MS)was used to identify odour-active compounds.The results showed that roasting,extraction techniques and filtration process influenced sensory perception and the acceptability of sesame oils.Consumers liked roasted sesame oils more than the cold-pressed sesame oil and liked the aqueous extracted sesame oil the most.Sensory attributes"sweet smell","mellow","roasted","nutty","persistent","high-intense flavour"and"cooked sesame seed flavour"were drivers of liking,while"green","raw sesame seed","rancid","woody"and"fishy"were drivers of disliking."Burnt"flavour was liked by some while disliked by others.Pyrazines contributed to roasted flavour;2-acetylpyrrole,acetophenone and furfural contributed to nutty flavour;2-pentyl-furan,5-methyl-2-furancarboxaldehyde,and 2-phenyl-2-butenal contributed to sweet odour in the roasted sesame seeds.Nonanal,hexanal,1-hexanol and ocimene were responsible for the"green"flavour perceived in the cold-pressed oil.This study provides valuable information for sesame manufacturers on how to improve the sensory qualities of sesame oils through process manipulation to meet the needs of diverse consumers.

Synthesis and ultraviolet/aggregation-induced emission investigation of novel tetraphenylvinyl hydrazone derivatives: efficient multimodal chemosensors for fluoride ion

Herein,three novel tetraphenylethylene hydrazone chemosensors TC12,SC16,and TC16 are prepared for the selective detection of F−.Two NH and one C=N units are incorporated into the sensors for better colorimetric responses,whereas the tetraphenyl unit is in charge of the aggregation-induced emission effect.Among them,compounds SC16 and TC16 form stable gels with some organic solvents.All the tetrahydrofuran/H2O solutions of the three compounds exhibit aggregation-induced emission effect,whereby the fluorescence emission increases by varying degrees with the volume of poor solvent water.Moreover,good aggregation-induced emission effects are observed in the self-assembly of SC16 and TC16.As a sample chemosensor,TC12 in tetrahydrofuran responds to F−selectively with high sensitivity,with the colorimetric and fluorometric detection limits of 8.25×10^(−7) mol·L^(-1) and 2.69×10^(−7) mol·L^(-1),respectively.The reversible gel-sol-gel phase transition and color changes indicate that both SC16-dimethyl sulfoxide and TC16-ethyl acetate gels specifically respond to F-with good sensitivity.The detection results are well supported by ultraviolet-visible spectroscopy,fluorescent spectroscopy,and 1H nuclear magnetic resonance.More importantly,the driving forces of gelation are visually clarified through the single crystal X-ray analysis of compound TOMe.

Biomarker-targeted fluorescent probes for breast cancer imaging

Breast cancer has become a common tumor worldwide which seriously endangers people＇s health. Earlydiagnosis and treatment are particularly urgent in order to reduce the onset risk, mortality, and prolongthe five-year survival rate. Therefore, we need a kind of diagnosis and treatment technology with highspecificity, sensitivity and selectivity. In recent years, because of its unique properties in biologicalapplications, fluorescence imaging has become an attractive research subject. Fluorescence imagingoffers innovative ideas of targetable recognition of breast cancer cells, breast cancer imaging in vivoanimal models, anticancer drugs delivery for guiding the mammary surgery via a noninvasive way withhigh sensitively and specifically. In this review, we summarized the recent advances of fluorescent probesfor breast cancer imaging, which were classified according to different biomarkers the probes recognized.Moreover, we discussed the strengths, built-in problems as well as the challenges about the fluorescentprobe as a unique potential method for the better application in breast cancer diagnosis and treatment.~ 2018 Chinese Chemical Society and Institute of Materia Medica, Chinese Academy of Medical Sciences.