What is already known about this topic?Diarrhea represents a substantial public health issue,contributing globally to a high number of pediatric medical consultations,hospital admissions,and mortality rates.What is ad...What is already known about this topic?Diarrhea represents a substantial public health issue,contributing globally to a high number of pediatric medical consultations,hospital admissions,and mortality rates.What is added by this report?An increase in diarrheal frequency serves as a critical benchmark for evaluating severity.The predominant pathogens associated with pediatric diarrhea are rotavirus and norovirus,with co-infections exerting a notable compounding effect that leads to more severe diarrhea.What are the implications for public health practice?Implementing sensitive diagnostic techniques and comprehensive monitoring is paramount in identifying co-infections.Such strategies can provide physicians with critical insights into disease progression,thus considerably reducing the burden of diarrhea.展开更多
基金Supported by the Three-year Action Plan for Promoting Clinical Skills and Innovation Ability of Municipal Hospitals(SHDC2022CRS039)Shanghai Natural Science Foundation(22ZR1462100,23ZR1464000,23ZR1463900)+4 种基金Medical Innovation Research Special Project of the Shanghai 2021“Science and Technology Innovation Action Plan”(21Y11922500,21Y11922400)the Talent Fund of Longhua Hospital affiliated to Shanghai University of Traditional Chinese Medicine(LH001.007)Natural Science Foundation of Gansu Province(21JR11RA182)Research Ward Construction Project of Shanghai Hospital Development Center(SHDC2022CRW006)Shanghai Municipal Education Commission Collaborative Innovation Center(A1-U21-205-902).
文摘What is already known about this topic?Diarrhea represents a substantial public health issue,contributing globally to a high number of pediatric medical consultations,hospital admissions,and mortality rates.What is added by this report?An increase in diarrheal frequency serves as a critical benchmark for evaluating severity.The predominant pathogens associated with pediatric diarrhea are rotavirus and norovirus,with co-infections exerting a notable compounding effect that leads to more severe diarrhea.What are the implications for public health practice?Implementing sensitive diagnostic techniques and comprehensive monitoring is paramount in identifying co-infections.Such strategies can provide physicians with critical insights into disease progression,thus considerably reducing the burden of diarrhea.