In order to know about the influences of disturbance on the operating performance, the present work developed the overall dynamic simulation model of the micro gas turbine and investigated the control system under the...In order to know about the influences of disturbance on the operating performance, the present work developed the overall dynamic simulation model of the micro gas turbine and investigated the control system under the disturbances of environmental temperature and unit load. The response processes of main parameters have been obtained. It found that the compressor pressure ratio and the fuel flow rate increase in the case of natural gas being replaced by pine gas. When the system reaches a new steady state, the main parameters change to different values. The output power decreases with the declining of the air mass flow when the ambient temperature rises, the biomass gas mass flow rate increases under the regulation of the control system to maintain the output power and rotating speed in which the thermal efficiency reduces by 1.40%. The thermal efficiency enhances with the increase of output load. The control system can quickly and effectively act to maintain the key parameters at desired value.展开更多
Multiple quantum coherences are often employed to describe quantum many-body dynamics in nuclear spin systems and recently,to characterize quantum phase transitions in trapped ions.Here we investigate the multiple-qua...Multiple quantum coherences are often employed to describe quantum many-body dynamics in nuclear spin systems and recently,to characterize quantum phase transitions in trapped ions.Here we investigate the multiple-quantum-coherence dynamics of a spin-1 Bose–Einstein condensate.By adjusting the quadratic Zeeman shift,the condensate exhibits three quantum phases.Our numerical results show that the spectrum of multiple quantum coherence does indeed catch the quantum critical points.More importantly,with only a few low-order multiple quantum coherences,the spin-1 condensate exhibits rich signals of the many-body dynamics,beyond conventional observables.The experimental implementation of such multiple quantum coherence protocol is also discussed.展开更多
As a common clinical disease, fracture is often accompanied by pain, swelling, bleeding as well as other symptoms and has a high disability rate, even threatening life, seriously endangering patients’ physical and ps...As a common clinical disease, fracture is often accompanied by pain, swelling, bleeding as well as other symptoms and has a high disability rate, even threatening life, seriously endangering patients’ physical and psychological health and quality of life. Medical practitioners take many strategies for the treatment of fracture healing, including Traditional Chinese Medicine(TCM). In the early stage of fracture healing,the local fracture is often in a state of hypoxia, accompanied by the expression of hypoxia inducible factor-1α(HIF-1α), which is beneficial to wound healing. Through literature mining, we thought that hypoxia, HIF-1α and downstream factors affected the mechanism of fracture healing, as well as dominated this process. Therefore, we reviewed the local characteristics and related signaling pathways involved in the fracture healing process and summarized the intervention of TCM on these mechanisms,in order to inspirit the new strategy for fracture healing, as well as elaborate on the possible principles of TCM in treating fractures based on the HIF molecular mechanism.展开更多
Animal models and static cultures of intestinal epithelial cells are commonly used platforms for exploring mercury ion(Hg(II))transport.However,they cannot reliably simulate the human intestinal microenvironment and m...Animal models and static cultures of intestinal epithelial cells are commonly used platforms for exploring mercury ion(Hg(II))transport.However,they cannot reliably simulate the human intestinal microenvironment and monitor cellular physiology in situ;thus,the mechanism of Hg(II)transport in the human intestine is still unclear.Here,a gut-on-a-chip integrated with transepithelial electrical resistance(TEER)sensors and electrochemical sensors is proposed for dynamically simulating the formation of the physical intestinal barrier and monitoring the transport and absorption of Hg(II)in situ.The cellular microenvironment was recreated by applying fluid shear stress(0.02 dyne/cm^(2))and cyclic mechanical strain(1%,0.15 Hz).Hg(II)absorption and physical damage to cells were simultaneously monitored by electrochemical and TEER sensors when intestinal epithelial cells were exposed to different concentrations of Hg(II)mixed in culture medium.Hg(II)absorption increased by 23.59%when tensile strain increased from 1%to 5%,and the corresponding expression of Piezo1 and DMT1 on the cell surface was upregulated.展开更多
文摘In order to know about the influences of disturbance on the operating performance, the present work developed the overall dynamic simulation model of the micro gas turbine and investigated the control system under the disturbances of environmental temperature and unit load. The response processes of main parameters have been obtained. It found that the compressor pressure ratio and the fuel flow rate increase in the case of natural gas being replaced by pine gas. When the system reaches a new steady state, the main parameters change to different values. The output power decreases with the declining of the air mass flow when the ambient temperature rises, the biomass gas mass flow rate increases under the regulation of the control system to maintain the output power and rotating speed in which the thermal efficiency reduces by 1.40%. The thermal efficiency enhances with the increase of output load. The control system can quickly and effectively act to maintain the key parameters at desired value.
基金supported by the NSAF under Grant No.U1930201the National Natural Science Foundation of China(NSFC)under Grant Nos.12274331,91836101,12135018,12204428the Innovation Program for Quantum Science and Technology under Grant No.2021ZD0302100。
文摘Multiple quantum coherences are often employed to describe quantum many-body dynamics in nuclear spin systems and recently,to characterize quantum phase transitions in trapped ions.Here we investigate the multiple-quantum-coherence dynamics of a spin-1 Bose–Einstein condensate.By adjusting the quadratic Zeeman shift,the condensate exhibits three quantum phases.Our numerical results show that the spectrum of multiple quantum coherence does indeed catch the quantum critical points.More importantly,with only a few low-order multiple quantum coherences,the spin-1 condensate exhibits rich signals of the many-body dynamics,beyond conventional observables.The experimental implementation of such multiple quantum coherence protocol is also discussed.
基金This work is financially supported by National Natural Science Foundation of China(No.82060877,82104527)the Science and Technology Planning Project of Tibet Autonomous Region(No.XZ202101ZD 0022G)Fundamental Research Funds for the Central Universities(No.lzujbky-2022-ct03).
文摘As a common clinical disease, fracture is often accompanied by pain, swelling, bleeding as well as other symptoms and has a high disability rate, even threatening life, seriously endangering patients’ physical and psychological health and quality of life. Medical practitioners take many strategies for the treatment of fracture healing, including Traditional Chinese Medicine(TCM). In the early stage of fracture healing,the local fracture is often in a state of hypoxia, accompanied by the expression of hypoxia inducible factor-1α(HIF-1α), which is beneficial to wound healing. Through literature mining, we thought that hypoxia, HIF-1α and downstream factors affected the mechanism of fracture healing, as well as dominated this process. Therefore, we reviewed the local characteristics and related signaling pathways involved in the fracture healing process and summarized the intervention of TCM on these mechanisms,in order to inspirit the new strategy for fracture healing, as well as elaborate on the possible principles of TCM in treating fractures based on the HIF molecular mechanism.
基金supported by the Taishan Scholars Program of Shandong Province (No.tsqn201812087)the National Natural Science Foundation of China (No.61901239)+1 种基金Qingchuang Science and Technology Plan Foundation for Colleges and Universities in Shandong Province (No.2019KJB009)the Young Ph.D.Cooperation Foundation of Qilu University of Technology (Shandong Academy of Sciences) (No.2019BSHZ002).
文摘Animal models and static cultures of intestinal epithelial cells are commonly used platforms for exploring mercury ion(Hg(II))transport.However,they cannot reliably simulate the human intestinal microenvironment and monitor cellular physiology in situ;thus,the mechanism of Hg(II)transport in the human intestine is still unclear.Here,a gut-on-a-chip integrated with transepithelial electrical resistance(TEER)sensors and electrochemical sensors is proposed for dynamically simulating the formation of the physical intestinal barrier and monitoring the transport and absorption of Hg(II)in situ.The cellular microenvironment was recreated by applying fluid shear stress(0.02 dyne/cm^(2))and cyclic mechanical strain(1%,0.15 Hz).Hg(II)absorption and physical damage to cells were simultaneously monitored by electrochemical and TEER sensors when intestinal epithelial cells were exposed to different concentrations of Hg(II)mixed in culture medium.Hg(II)absorption increased by 23.59%when tensile strain increased from 1%to 5%,and the corresponding expression of Piezo1 and DMT1 on the cell surface was upregulated.
