Plants possess diverse cell types and intricate regulatory mechanisms to adapt to the ever-changing environment of nature.Various strategies have been employed to study cell types and their developmental progressions,...Plants possess diverse cell types and intricate regulatory mechanisms to adapt to the ever-changing environment of nature.Various strategies have been employed to study cell types and their developmental progressions,including single-cell sequencing methods which provide high-dimensional catalogs to address biological concerns.In recent years,single-cell sequencing technologies in transcriptomics,epigenomics,proteomics,metabolomics,and spatial transcriptomics have been increasingly used in plant science to reveal intricate biological relationships at the single-cell level.However,the application of single-cell technologies to plants is more limited due to the challenges posed by cell structure.This review outlines the advancements in single-cell omics technologies,their implications in plant systems,future research applications,and the challenges of single-cell omics in plant systems.展开更多
基金supported by the National Natural Science Foundation of China(Grant No.32170574)the start-up fund of Peking University Institute of Advanced Agricultural Sciences,the Shandong Laboratory of Advanced Agricultural Sciences,the National Key R&D of China(Grant No.2018YFA0507101)+2 种基金the Program for Guangdong Introducing Innovative and Entrepreneurial Teams(Grant No.2016ZT06S172)the Taishan Scholars Programthe Yuandu Scholars Program,China.
文摘Plants possess diverse cell types and intricate regulatory mechanisms to adapt to the ever-changing environment of nature.Various strategies have been employed to study cell types and their developmental progressions,including single-cell sequencing methods which provide high-dimensional catalogs to address biological concerns.In recent years,single-cell sequencing technologies in transcriptomics,epigenomics,proteomics,metabolomics,and spatial transcriptomics have been increasingly used in plant science to reveal intricate biological relationships at the single-cell level.However,the application of single-cell technologies to plants is more limited due to the challenges posed by cell structure.This review outlines the advancements in single-cell omics technologies,their implications in plant systems,future research applications,and the challenges of single-cell omics in plant systems.
