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直肠癌切除术后吻合口漏与患者长期预后的关系 被引量:6
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作者 王文跃 Susanne Merkel +1 位作者 Paul Hermanek werner hohenberger 《中日友好医院学报》 2001年第6期327-330,共4页
目的 :探讨吻合口漏与直肠癌术后局部复发和生存率的关系。方法 :对 1978年~ 1996年行直肠癌前切除术的 814例患者进行随访 ,并对发生与未发生吻合口漏患者的预后进行了单因素和多因素分析。结果 :814例中 89例 (10 .9% )发生了吻合口... 目的 :探讨吻合口漏与直肠癌术后局部复发和生存率的关系。方法 :对 1978年~ 1996年行直肠癌前切除术的 814例患者进行随访 ,并对发生与未发生吻合口漏患者的预后进行了单因素和多因素分析。结果 :814例中 89例 (10 .9% )发生了吻合口漏。经过Kaplan Meier生存曲线分析 ,患者总体 5a局部复发率是 13.6 %。多因素分析显示吻合口漏是影响肿瘤局部复发的独立危险因素 (相对危险度为 1.7,P =0 .0 4 18) ,也是影响肿瘤相关生存率的独立危险因素 (相对危险度为 1.6 ,P =0 .0 172 )。结论 :吻合口漏是影响直肠癌患者术后局部复发率和肿瘤相关生存率的危险因素。 展开更多
关键词 局部复发 直肠腺癌 吻合口漏 手术后 预后 生态率 切除术
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Recent results of laparoscopic surgery in inflammatory bowel disease 被引量:7
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作者 Hermann Kessler Jonas Mudter werner hohenberger 《World Journal of Gastroenterology》 SCIE CAS CSCD 2011年第9期1116-1125,共10页
Inflammatory bowel diseases are an ideal indication for the laparoscopic surgical approach as they are basically benign diseases not requiring lymphadenectomy and extended mesenteric excision;well-established surgical... Inflammatory bowel diseases are an ideal indication for the laparoscopic surgical approach as they are basically benign diseases not requiring lymphadenectomy and extended mesenteric excision;well-established surgical procedures are available for the conventional approach.Inflammatory alterations and fragility of the bowel and mesentery,however,may demand a high level of laparoscopic experience.A broad spectrum of operations from the rather easy enterostomy formation for anal Crohn’s disease(CD)to restorative proctocolectomies for ulcerative colitis(UC)may be managed laparoscopically.The current evidence base for the use of laparoscopic techniques in the surgical therapy of inflammatory bowel diseases is presented.CD limited to the terminal ileum has become a common indication for laparoscopic surgical therapy.In severe anal CD, laparoscopic stoma formation is a standard procedure with low morbidity and short operative time.Studies comparing conventional and laparoscopic bowel resections,have found shorter times to first postoperative bowel movements and shorter hospital stays as well as lower complication rates in favour of the laparoscopic approach.Even complicated cases with previous surgery,abscess formation and enteric fistulas may be op-erated on laparoscopically with a low morbidity.In UC, restorative proctocolectomy is the standard procedure in elective surgery.The demanding laparoscopic approach is increasingly used,however,mainly in major centers; its feasibility has been proven in various studies.An increased body mass index and acute inflammation of the bowel may be relative contraindications.Short and longterm outcomes like quality of life seem to be equivalent for open and laparoscopic surgery.Multiple studies have proven that the laparoscopic approach to CD and UC is a safe and successful alternative for selected patients. The appropriate selection criteria are still under investigation.Technical considerations are playing an important role for the complexity of both diseases. 展开更多
关键词 Crohn’s disease Ulcerative colitis LAPAROSCOPIC COLORECTAL SURGERY
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