Shape morphing is a critical aptitude for the survival of organisms and is determined by anisotropic tissue composition and directional orientation of micro-and nanostructures within cell walls,resulting in diferent s...Shape morphing is a critical aptitude for the survival of organisms and is determined by anisotropic tissue composition and directional orientation of micro-and nanostructures within cell walls,resulting in diferent swelling behaviors.Recent eforts have been dedicated to mimicking the behaviors that nature has perfected over billions of years.We present a robust strategy for preparing 3D periodically patterned single-component sodium alginate hydrogel sheets cross-linked with Ca^(2+)ions,which can reversibly deform and be retained into various desirable inside-out shapes as triggered by biocompatible ions(Na^(+)/Ca^(2+)).By changing the orientations of the patterned microchannels or triggering with Na^(+)/Ca^(2+)ions,various 3D twisting,tubular,and plantinspired architectures can be facilely programmed.Not only can the transformation recover their initial shapes reversibly,but also it can keep the designated shapes without continuous stimuli.Tese inside-out 3D reversible ion-triggered hydrogel transformations shall inspire more attractive applications in tissue engineering,biomedical devices,and sof robotics felds.展开更多
基金We are indebted to Dr.Massimiliano Galluzzi for performing AFM analysis of the samples.This work was supported by the National Key R&D Program of China(2017YFA0701303,2016YFA0201001)National Natural Science Foundation of China(21404116)+3 种基金the Youth Innovation Promotion Association of CAS,CAS Key Laboratory of Health Informatics,Shenzhen Institutes of Advanced Technology,Special Support Project for Outstanding Young Scholars of Guangdong Province(2015TQ01R292)Guangdong-Hong Kong Technology Cooperation Funding(2017A050506040)Shenzhen Science and Technology Innovation Committee(JCYJ20150316144521974,JCYJ20170818161757684,JCYJ2017-0413152640731)Shenzhen Peacock Plan.
文摘Shape morphing is a critical aptitude for the survival of organisms and is determined by anisotropic tissue composition and directional orientation of micro-and nanostructures within cell walls,resulting in diferent swelling behaviors.Recent eforts have been dedicated to mimicking the behaviors that nature has perfected over billions of years.We present a robust strategy for preparing 3D periodically patterned single-component sodium alginate hydrogel sheets cross-linked with Ca^(2+)ions,which can reversibly deform and be retained into various desirable inside-out shapes as triggered by biocompatible ions(Na^(+)/Ca^(2+)).By changing the orientations of the patterned microchannels or triggering with Na^(+)/Ca^(2+)ions,various 3D twisting,tubular,and plantinspired architectures can be facilely programmed.Not only can the transformation recover their initial shapes reversibly,but also it can keep the designated shapes without continuous stimuli.Tese inside-out 3D reversible ion-triggered hydrogel transformations shall inspire more attractive applications in tissue engineering,biomedical devices,and sof robotics felds.
