Allergic asthma is an inflammatory disease of the airways characterized by recurrent episodes of wheezing,bronchoconstriction,and airway hyperresponsiveness(AHR)[1].In recent years,allergic asthma has become a heated ...Allergic asthma is an inflammatory disease of the airways characterized by recurrent episodes of wheezing,bronchoconstriction,and airway hyperresponsiveness(AHR)[1].In recent years,allergic asthma has become a heated public health problem because of the highly increased incidence and prevalence[2].The main pathogenesis of asthma is airway inflammation and AHR.AHR is caused by an imbalance of Th1/Th2 cells with predominance to Th2,whereas airway inflammation is caused by increased levels of Th2 cytokine[3].Major effects of pathological changes in the respiratory include eosinophil infiltration,bronchial epithelial cell damage,obstruction of the mucus plug,and thickening of the submucosal muscle layer[4,5].展开更多
基金supported by the National Natural Science Foundation of China[Grant Nos.31971562 and 81671586].
文摘Allergic asthma is an inflammatory disease of the airways characterized by recurrent episodes of wheezing,bronchoconstriction,and airway hyperresponsiveness(AHR)[1].In recent years,allergic asthma has become a heated public health problem because of the highly increased incidence and prevalence[2].The main pathogenesis of asthma is airway inflammation and AHR.AHR is caused by an imbalance of Th1/Th2 cells with predominance to Th2,whereas airway inflammation is caused by increased levels of Th2 cytokine[3].Major effects of pathological changes in the respiratory include eosinophil infiltration,bronchial epithelial cell damage,obstruction of the mucus plug,and thickening of the submucosal muscle layer[4,5].
