目的:探讨弥散张量磁共振成像技术(Diffusion tensor imaging,DTI)中的基于纤维束示踪空间统计方法(Tracer based spatial statistics,TBSS)对无先兆偏头痛患者(Migraine without aura,MWoA)脑白质微结构的变化模式及诊断价值。方法:前...目的:探讨弥散张量磁共振成像技术(Diffusion tensor imaging,DTI)中的基于纤维束示踪空间统计方法(Tracer based spatial statistics,TBSS)对无先兆偏头痛患者(Migraine without aura,MWoA)脑白质微结构的变化模式及诊断价值。方法:前瞻性收集22例MWoA患者(MWoA组)和24例健康对照组(HC组)并进行全脑DTI检查,使用TBSS方法比较MWoA患者和健康对照组在白质微结构水平上的差异,并提取差异脑区的FA值。采用Spearman相关性分析来探讨差异脑区FA值与病程、头疼发作频率、偏头痛失能程度评估量表(MIDAS)、数字疼痛评估量表(NRS)相关性。通过受试者工作特征(ROC)曲线分析差异脑区的FA值是否可以用来评价无先兆偏头痛的诊断价值。结果:与健康对照组相比,MWoA患者在胼胝体膝部、胼胝体体部、胼胝体压部、双侧内囊前肢、右侧内囊后肢、双侧前放射冠、右侧上放射冠、右侧外囊、双侧上纵束的FA值降低。相关性分析发现在MWoA组中,左侧前放射冠FA值与NRS评分呈负相关(r=-0.425,P<0.05)。ROC分析显示胼胝体膝部、胼胝体体部、胼胝体压部、双侧内囊前肢、右侧内囊后肢、右侧前放射冠FA值对于MWoA具有一定的诊断价值,其AUC值分别为0.8627、0.7576、0.7614、0.7879、0.7292、0.7064、0.7311,均P<0.05。结论:DTI所示FA值可用于诊断MWoA。展开更多
Soils in the hydro-fluctuation belts of the reservoirs are most highly influenced by the special hydro-conditions and reservoir operation,leading to unique soil erosion process and largely accelerate soil erosion inte...Soils in the hydro-fluctuation belts of the reservoirs are most highly influenced by the special hydro-conditions and reservoir operation,leading to unique soil erosion process and largely accelerate soil erosion intensity.The present study aimed to estimate soil erosion rate in the hydro-fluctuation belt of the Pubugou Reservoir,Southwest China,based on the framework of Universal Soil Loss Equation(USLE).An attempt has been made to modify the original USLE by including the reservoir water erosivity(W),a new factor into the model.Soil erosion rate from different land use types were quantitatively estimated,using the USLE and the modified USLE respectively.Field observation showed that soil erosion rate in dry farmland,bare land and grassland was 4700,44600 and 5050 t/km2,respectively.The erosion rate assessed by the modified USLE was closely related to that recorded from the field monitoring data.The findings of this study clearly highlight the importance of inclusion of the W factor to the original USLE model while assessing soil erosion in the reservoir hydro-fluctuation belt.展开更多
文摘目的:探讨弥散张量磁共振成像技术(Diffusion tensor imaging,DTI)中的基于纤维束示踪空间统计方法(Tracer based spatial statistics,TBSS)对无先兆偏头痛患者(Migraine without aura,MWoA)脑白质微结构的变化模式及诊断价值。方法:前瞻性收集22例MWoA患者(MWoA组)和24例健康对照组(HC组)并进行全脑DTI检查,使用TBSS方法比较MWoA患者和健康对照组在白质微结构水平上的差异,并提取差异脑区的FA值。采用Spearman相关性分析来探讨差异脑区FA值与病程、头疼发作频率、偏头痛失能程度评估量表(MIDAS)、数字疼痛评估量表(NRS)相关性。通过受试者工作特征(ROC)曲线分析差异脑区的FA值是否可以用来评价无先兆偏头痛的诊断价值。结果:与健康对照组相比,MWoA患者在胼胝体膝部、胼胝体体部、胼胝体压部、双侧内囊前肢、右侧内囊后肢、双侧前放射冠、右侧上放射冠、右侧外囊、双侧上纵束的FA值降低。相关性分析发现在MWoA组中,左侧前放射冠FA值与NRS评分呈负相关(r=-0.425,P<0.05)。ROC分析显示胼胝体膝部、胼胝体体部、胼胝体压部、双侧内囊前肢、右侧内囊后肢、右侧前放射冠FA值对于MWoA具有一定的诊断价值,其AUC值分别为0.8627、0.7576、0.7614、0.7879、0.7292、0.7064、0.7311,均P<0.05。结论:DTI所示FA值可用于诊断MWoA。
基金financially supported by the National Key Research and Development Program of China(Grant No.SQ2018YFD080041)the Sichuan Science and Technology Program(Grant No.2017SZ0188)。
文摘Soils in the hydro-fluctuation belts of the reservoirs are most highly influenced by the special hydro-conditions and reservoir operation,leading to unique soil erosion process and largely accelerate soil erosion intensity.The present study aimed to estimate soil erosion rate in the hydro-fluctuation belt of the Pubugou Reservoir,Southwest China,based on the framework of Universal Soil Loss Equation(USLE).An attempt has been made to modify the original USLE by including the reservoir water erosivity(W),a new factor into the model.Soil erosion rate from different land use types were quantitatively estimated,using the USLE and the modified USLE respectively.Field observation showed that soil erosion rate in dry farmland,bare land and grassland was 4700,44600 and 5050 t/km2,respectively.The erosion rate assessed by the modified USLE was closely related to that recorded from the field monitoring data.The findings of this study clearly highlight the importance of inclusion of the W factor to the original USLE model while assessing soil erosion in the reservoir hydro-fluctuation belt.
