国际卵巢肿瘤分析简单法则鉴别卵巢肿瘤良恶性的临床价值分析

目的:分析国际卵巢肿瘤分析(IOTA)简单法则鉴别卵巢肿瘤良恶性的临床价值。方法:回顾性选取2020年1月—2022年12月于孝感市中心医院经病理检查确诊的卵巢肿瘤患者386例作为研究对象,由低年资组医师和高年资组医师在不知病理诊断结果情况下,依靠经验和应用IOTA简单法则分别对卵巢肿瘤进行定性诊断,以术后病理诊断结果为“金标准”,比较两组医师经验性诊断与应用IOTA简单法则对卵巢肿瘤良恶性的诊断效能。结果:386例卵巢肿瘤中,良性肿瘤294例,恶性肿瘤92例。低年资组医师经验诊断卵巢肿瘤良恶性的准确率、灵敏度、特异度、阳性预测值、阴性预测值低于低年资组应用IOTA简单法则、高年资组经验诊断、高年资组应用IOTA简单法则,差异有统计学意义(P<0.05);高年资组经验诊断、高年资组应用IOTA简单法则以及低年资组应用IOTA简单法则诊断卵巢肿瘤良恶性的准确率、灵敏度、特异度、阳性预测值、阴性预测值比较,差异无统计学意义(P>0.05)。结论:低年资医师应用IOTA简单法则对卵巢肿瘤良恶性的诊断效能与高年资医师经验诊断的效能相当,可帮助低年资医师提高诊断准确性,减少漏诊及误诊。

新型陈化技术对六堡茶品质的影响

陈化是提升六堡茶品质的重要工序,为明确新型陈化技术对六堡茶品质的影响,比较了新型陈化技术处理与正常仓储的六堡茶的感官品质与理化成分。结果表明,经过新型陈化技术处理的六堡茶汤色更红,香气滋味更显陈味,水浸出物、茶多酚、游离氨基酸含量低于正常仓储的六堡茶。新型陈化技术为稳定提升六堡茶品质提供了新的便捷途径。

Coordinative Development Between Land Use Change and Regional Population-Resources-Environment-Development System—A Case Study of Jiangsu Province

Land use change has significant influence on the operation of the PopulationResources-Environment-De-velopment (PRED) System. Moderate land use is the key factor to ensure the coordinative and sustainable development between land use and PRED system. Based on the internal relationship between land use and PRED system, a PRED evaluation index system and a Press-Status-Response (PSR) model were established in this study. According to the expounding on the mechanism of the PSR model, we investigated the coordinative development between the changes of regional land use and PRED system taking Jiangsu Province as an example. The results showed that the orders of the Synthetic Index of Land Use (SILU) and the Variation of PRED Index (VPI) in Jiangsu are both the southern Jiangsu>the central Jiangsu>the northern Jiangsu. A cubic curve model was used to fit the relationship between the VPI and SILU. The inflection point of VPI was situated in 5.0 of SILU. When SILU was below 5.0, VPI increased with SILU, which will be helpful to the coordinative development between land use and PRED system. Based on those results, it is suggested that the land use degree of the southern Jiangsu, especially that of Nanjing City, should be moderately controlled at present, while land resources of the central Jiangsu and the northern Jiangsu should be further exploited.

基于高分辨质谱结合主成分分析技术评价发酵过程对六堡茶关键品质成分的影响

六堡茶是一种产自广西六堡的微生物发酵型茶叶,其有别于其他茶叶的最主要环节是长达半年至3年的窖藏。为研究六堡茶加工过程中关键成分的变化,分析了不同生产阶段的六堡茶中总多糖、咖啡碱、总多酚及茶黄素等主要成分的含量差异;并基于超高效液相色谱-四级杆静电场轨道阱质谱系统(UPLC-Q-Exactive)结合主成分分析方法,探究渥堆发酵及窖藏工艺中六堡茶化学成分变化规律。结果表明,六堡茶原料经过渥堆发酵后,总多糖含量上升,由0.63%上升至2.15%;窖藏后,含量变化不大。咖啡碱含量整体变化差异不大,含量为1.96%~2.15%。原料中的总多酚含量为20.73%,渥堆发酵后下降为17.93%;窖藏后,含量下降为12.62%,整体呈现出下降的趋势。渥堆发酵后茶黄素含量由原料的0.05%上升至0.21%,窖藏后再次下降至0.10%,整体较原料呈升高趋势。主成分分析结果表明,渥堆发酵及窖藏前后的六堡茶样品与原料能够良好区分,表明其化学成分随渥堆发酵及窖藏过程产生显著变化。通过数据库比对,从渥堆发酵及窖藏后差异较大的化合物中共鉴定出29种化合物,包括酚酸类、黄烷醇类、黄酮及黄酮苷类物质。其中预测为部分酚酸类、黄酮及苷类的物质,其相对含量在渥堆发酵环节下降,而在窖藏环节重新回升。揭示了六堡茶中主要成分在关键工艺环节的变化规律,为定义品质关键成分、预测健康功效提供了科学数据。