Elemental concentration distributions in space have been analyzed using different approaches. These analyses are of great significance for the quantitative characterization of various kinds of distribution patterns. F...Elemental concentration distributions in space have been analyzed using different approaches. These analyses are of great significance for the quantitative characterization of various kinds of distribution patterns. Fractal and multi-fractal methods have been extensively applied to this topic. Traditionally, approximately linear-fractal laws have been regarded as useful tools for characterizing the self-similarities of element concentrations. But, in nature, it is not always easy to find perfect linear fractal laws. In this paper the parabolic fractal model is used. First a two dimensional multiplicative multi-fractal cascade model is used to study the concentration patterns. The results show the parabolic fractal （PF） properties of the concentrations and the validity of non-linear fractal analysis. By dividing the studied area into four sub-areas it was possible to show that each part follows a non-linear parabolic fractal law and that the dispersion within each part varies. The ratio of the polynomial coefficients of the fitted parabolic curves can reflect, to some degree, the relative concentration and dispersal distribution patterns. This can provide new insight into the ore-forming potential in space. The parabofic fractal evaluations of ore-forming potential for the four suhareas are in good agreement with field investigation work and geochemical mapping results based on analysis of the original data.展开更多
目的:观察左卡尼汀联合环磷腺苷对病毒性心肌炎(VMC)患者的疗效及对血清干扰素(IFN)-γ和白介素(IL)-4水平的影响。方法: 2017年到2018年于我院治疗的VMC患者132例被随机均分为左卡尼汀组(在常规治疗基础上接受左卡尼汀治疗)和联合治疗...目的:观察左卡尼汀联合环磷腺苷对病毒性心肌炎(VMC)患者的疗效及对血清干扰素(IFN)-γ和白介素(IL)-4水平的影响。方法: 2017年到2018年于我院治疗的VMC患者132例被随机均分为左卡尼汀组(在常规治疗基础上接受左卡尼汀治疗)和联合治疗组(在左卡尼汀组基础上接受环磷腺苷治疗),两组均治疗2周。观察比较两组治疗前、后外周血血清IFN-γ、IL-4、心肌肌钙蛋白T(cTnT)、肌酸激酶同工酶(CK-MB)水平,临床疗效以及药物不良反应。结果:与治疗前比较,治疗2周后两组血清IL-4水平均显著升高,血清IFN-γ、cTnT和CK-MB水平均显著降低, P 均=0.001;与左卡尼汀组比较,联合治疗组血清IL-4水平[(47.43±9.17)ng/ml比(55.38±10.23)ng/ml]升高更显著,血清IFN-γ[(65.22±11.82)ng/ml比(52.18±10.06)ng/ml]、cTnT[(0.37±0.09)ng/ml比(0.18±0.03)ng/ml]和CK-MB[(28.56±5.34)U/L比(16.22±3.47)U/L]水平降低更显著, P 均=0.001。联合治疗组治疗总有效率显著高于左卡尼汀组(92.4%比80.3%), P =0.042。两组药物不良反应率无显著差异, P =0.784。结论:左卡尼汀联合环磷腺苷可以显著降低病毒性心肌炎患者外周血IFN-γ水平和升高IL-4水平,调节Th1/Th2失衡,疗效显著,安全性好。展开更多
基金Projects 40502029, 40472146 and 40373003 supported by the Natural Science Foundation of ChinaGPMR2007-11 by the Key Lab of GeologicalProcesses and Mineral Resources
文摘Elemental concentration distributions in space have been analyzed using different approaches. These analyses are of great significance for the quantitative characterization of various kinds of distribution patterns. Fractal and multi-fractal methods have been extensively applied to this topic. Traditionally, approximately linear-fractal laws have been regarded as useful tools for characterizing the self-similarities of element concentrations. But, in nature, it is not always easy to find perfect linear fractal laws. In this paper the parabolic fractal model is used. First a two dimensional multiplicative multi-fractal cascade model is used to study the concentration patterns. The results show the parabolic fractal （PF） properties of the concentrations and the validity of non-linear fractal analysis. By dividing the studied area into four sub-areas it was possible to show that each part follows a non-linear parabolic fractal law and that the dispersion within each part varies. The ratio of the polynomial coefficients of the fitted parabolic curves can reflect, to some degree, the relative concentration and dispersal distribution patterns. This can provide new insight into the ore-forming potential in space. The parabofic fractal evaluations of ore-forming potential for the four suhareas are in good agreement with field investigation work and geochemical mapping results based on analysis of the original data.
文摘目的:观察左卡尼汀联合环磷腺苷对病毒性心肌炎(VMC)患者的疗效及对血清干扰素(IFN)-γ和白介素(IL)-4水平的影响。方法: 2017年到2018年于我院治疗的VMC患者132例被随机均分为左卡尼汀组(在常规治疗基础上接受左卡尼汀治疗)和联合治疗组(在左卡尼汀组基础上接受环磷腺苷治疗),两组均治疗2周。观察比较两组治疗前、后外周血血清IFN-γ、IL-4、心肌肌钙蛋白T(cTnT)、肌酸激酶同工酶(CK-MB)水平,临床疗效以及药物不良反应。结果:与治疗前比较,治疗2周后两组血清IL-4水平均显著升高,血清IFN-γ、cTnT和CK-MB水平均显著降低, P 均=0.001;与左卡尼汀组比较,联合治疗组血清IL-4水平[(47.43±9.17)ng/ml比(55.38±10.23)ng/ml]升高更显著,血清IFN-γ[(65.22±11.82)ng/ml比(52.18±10.06)ng/ml]、cTnT[(0.37±0.09)ng/ml比(0.18±0.03)ng/ml]和CK-MB[(28.56±5.34)U/L比(16.22±3.47)U/L]水平降低更显著, P 均=0.001。联合治疗组治疗总有效率显著高于左卡尼汀组(92.4%比80.3%), P =0.042。两组药物不良反应率无显著差异, P =0.784。结论:左卡尼汀联合环磷腺苷可以显著降低病毒性心肌炎患者外周血IFN-γ水平和升高IL-4水平,调节Th1/Th2失衡,疗效显著,安全性好。
