In the past few decades,the irrational use of water resources has resulted in many issues such as land subsidence in the North China Plain(NCP),hindering its socio-economic development.An accurate understanding of wat...In the past few decades,the irrational use of water resources has resulted in many issues such as land subsidence in the North China Plain(NCP),hindering its socio-economic development.An accurate understanding of water resource changes is important for the allocation of water resources in the NCP.In this study,we employed Gravity Recovery and Climate Experiment(GRACE) satellite data to monitor the total water storage(TWS) change in the NCP during 2004–2019.Evapotranspiration,precipitation,and runoff during 2004–2019 were sequentially examined,using the water balance formula(WBF),to retrieve TWS change.Furthermore,the soil moisture,snow water equivalent,and canopy water storage from the Global Land Data Assimilation System were used to calculate the natural component of the TWS variations.A comparison of these results revealed the drivers of the changes in water resources.The results showed that:(1) overall TWS retrieved by GRACE decreased substantially as a consequence of human activity,while TWS obtained by WBF fluctuated periodically around zero under the impact of three natural drivers;(2) TWS in the NCP fell at a remarkable rate of-12.39 mm/y from 2004 to 2019,and the natural part of TWS experienced two significant declines,during 2004–2010 and 2013–2016;(3) variations in runoff,precipitation,and evapotranspiration from 2004 to 2019 were not significant,but human activities contributed more to the decreasing TWS than natural factors.This study provides a reference for water resource management and groundwater exploitation across the NCP under climate change.展开更多
目的研究松叶提取物对"过食膏粱厚味"型高尿酸血症大鼠尿酸生成排泄、肝功能及血脂水平的影响。方法将60只♂SD大鼠,随机分为正常对照组、模型对照组、别嘌醇(0.01 g·kg-1)阳性对照组、松叶提取物3个剂量组(10.0,5.0,2.5...目的研究松叶提取物对"过食膏粱厚味"型高尿酸血症大鼠尿酸生成排泄、肝功能及血脂水平的影响。方法将60只♂SD大鼠,随机分为正常对照组、模型对照组、别嘌醇(0.01 g·kg-1)阳性对照组、松叶提取物3个剂量组(10.0,5.0,2.5g·kg-(16)),每组10只。除正常对照组给予等体积蒸馏水,其余各组每天上午灌胃给予脂肪乳剂造模,下午灌胃给药,连续9周。观察大鼠一般行为学、摄食量、体质量,分别检测大鼠血清SUA、SCR、BUN、ALT、AST、TC、LDL-c含量;收集24 h尿液,记录UV,检测大鼠尿UUA、UCR含量,计算24 h UUA、FEUA、CUr、CCr,末次给药后测定血清和肝脏XOD、ADA、HGPRT活性。结果模型对照组大鼠体质量明显降低,血清SUA、SCR、BUN、ALT、TC、LDL-c水平以及血清和肝组织XOD、ADA活性显著升高,肝组织HGPRT活性显著降低,同时UUA、UCR、UV、24 h UUA、FEUA、CUr、CCr显著降低。松叶提取物能显著降低高尿酸血症大鼠血清SUA、SCR、BUN、ALT、TC、LDL-c水平,降低血清和肝组织XOD、ADA活性,升高肝组织HGPRT活性,并且升高UUA、UCR、UV、24 h UUA、FEUA、CUr、CCr。结论松叶提取物能有效降低HUA大鼠尿酸的生成并促进其排泄,且具有保肝、调血脂的功能。展开更多
基金supported by the National Key Research and Development Program of China (Grant No.2022YFF0711603)the Fundamental Research Funds for the Central Universities (Grant Nos.0209-14380093 and0209-14380097)+2 种基金the Frontiers Science Center for Critical Earth Material Cycling Fund (Grant No.JBGS2102)the National Natural Science Foundation of China (Grant No.41671423)the Ministry Science and Technology Development of China-Data Sharing Infrastructure of Earth System Science (Grant No.2005DKA32300)。
文摘In the past few decades,the irrational use of water resources has resulted in many issues such as land subsidence in the North China Plain(NCP),hindering its socio-economic development.An accurate understanding of water resource changes is important for the allocation of water resources in the NCP.In this study,we employed Gravity Recovery and Climate Experiment(GRACE) satellite data to monitor the total water storage(TWS) change in the NCP during 2004–2019.Evapotranspiration,precipitation,and runoff during 2004–2019 were sequentially examined,using the water balance formula(WBF),to retrieve TWS change.Furthermore,the soil moisture,snow water equivalent,and canopy water storage from the Global Land Data Assimilation System were used to calculate the natural component of the TWS variations.A comparison of these results revealed the drivers of the changes in water resources.The results showed that:(1) overall TWS retrieved by GRACE decreased substantially as a consequence of human activity,while TWS obtained by WBF fluctuated periodically around zero under the impact of three natural drivers;(2) TWS in the NCP fell at a remarkable rate of-12.39 mm/y from 2004 to 2019,and the natural part of TWS experienced two significant declines,during 2004–2010 and 2013–2016;(3) variations in runoff,precipitation,and evapotranspiration from 2004 to 2019 were not significant,but human activities contributed more to the decreasing TWS than natural factors.This study provides a reference for water resource management and groundwater exploitation across the NCP under climate change.
文摘目的研究松叶提取物对"过食膏粱厚味"型高尿酸血症大鼠尿酸生成排泄、肝功能及血脂水平的影响。方法将60只♂SD大鼠,随机分为正常对照组、模型对照组、别嘌醇(0.01 g·kg-1)阳性对照组、松叶提取物3个剂量组(10.0,5.0,2.5g·kg-(16)),每组10只。除正常对照组给予等体积蒸馏水,其余各组每天上午灌胃给予脂肪乳剂造模,下午灌胃给药,连续9周。观察大鼠一般行为学、摄食量、体质量,分别检测大鼠血清SUA、SCR、BUN、ALT、AST、TC、LDL-c含量;收集24 h尿液,记录UV,检测大鼠尿UUA、UCR含量,计算24 h UUA、FEUA、CUr、CCr,末次给药后测定血清和肝脏XOD、ADA、HGPRT活性。结果模型对照组大鼠体质量明显降低,血清SUA、SCR、BUN、ALT、TC、LDL-c水平以及血清和肝组织XOD、ADA活性显著升高,肝组织HGPRT活性显著降低,同时UUA、UCR、UV、24 h UUA、FEUA、CUr、CCr显著降低。松叶提取物能显著降低高尿酸血症大鼠血清SUA、SCR、BUN、ALT、TC、LDL-c水平,降低血清和肝组织XOD、ADA活性,升高肝组织HGPRT活性,并且升高UUA、UCR、UV、24 h UUA、FEUA、CUr、CCr。结论松叶提取物能有效降低HUA大鼠尿酸的生成并促进其排泄,且具有保肝、调血脂的功能。
