以甲醇对2种短指软珊瑚进行提取,检测提取物对各波段紫外线的吸收效果以表征其防晒活性,以酪氨酸酶抑制实验检测其美白活性,并以DPPH法检测其抗氧化活性,首次探讨了软珊瑚来源物质在化妆品开发中的应用潜力。结果表明,在防晒活性方面, S...以甲醇对2种短指软珊瑚进行提取,检测提取物对各波段紫外线的吸收效果以表征其防晒活性,以酪氨酸酶抑制实验检测其美白活性,并以DPPH法检测其抗氧化活性,首次探讨了软珊瑚来源物质在化妆品开发中的应用潜力。结果表明,在防晒活性方面, Sinularia compacta 和 Sinularia wanannensis 提取物对紫外线具有较强的吸收特性,随浓度增加其光吸收波段也随之扩大,浓度在5.0 mg/cm^3 以上时对280~400 nm波长范围的紫外线均有良好吸收,总体上 S. compacta 提取物的防晒活性略高于 S. wanannensis 提取物,两者对紫外线的吸收效果均优于阳性对照熊果苷和二苯甲酮, S. compacta 提取物在10.0 mg/cm^3 时对紫外线的吸收效果甚至与阳性对照芦丁相当,显示出较高的防紫外效能;在美白活性方面, S. compacta 和 S. wanannensis 提取物均有一定的抑制酪氨酸酶活性作用, S. compacta 和 S. wanannensis 提取物在此活性无显著性差异;在抗氧化活性方面, S. compacta 和 S. wanannensis 提取物均显示出优异的清除自由基能力,且其活性随浓度的升高而升高,在1.0~5.0 mg/cm^3 浓度下 S. compacta 和 S. wanannensis 提取物的抗氧化活性与阳性对照Vc相当,在10.0 mg/cm^3时 S. wanannensis 提取物的抗氧化活性显著高于 S. compacta 提取物和Vc。研究结果为开发软珊瑚源天然新型化妆品物质奠定了重要基础。展开更多
Diabetic retinopathy(DR),as a common microvascular complication of diabetes,is the result of the interaction of multiple factors and multiple mechanisms.Inflammation is one of the important pathophysiological mechanis...Diabetic retinopathy(DR),as a common microvascular complication of diabetes,is the result of the interaction of multiple factors and multiple mechanisms.Inflammation is one of the important pathophysiological mechanisms of DR.Leukocytes accumulate and adhere to the surface of endothelial cells,glial cell activation and its dysfunction,and the release of vascular endothelial growth factor,interleukin and other inflammatory factors are directly related to the occurrence and development of DR inflammation.Antiinflammation plays an important role in the treatment of DR.Studies have shown that traditional Chinese medicine has a unique advantage in targeting the inflammatory mechanism of DR.Therefore,the inflammatory cells,inflammatory factors and related Chinese medicines closely related to DR are reviewed,in order to provide references for the early prevention and treatment of DR.展开更多
文摘以甲醇对2种短指软珊瑚进行提取,检测提取物对各波段紫外线的吸收效果以表征其防晒活性,以酪氨酸酶抑制实验检测其美白活性,并以DPPH法检测其抗氧化活性,首次探讨了软珊瑚来源物质在化妆品开发中的应用潜力。结果表明,在防晒活性方面, Sinularia compacta 和 Sinularia wanannensis 提取物对紫外线具有较强的吸收特性,随浓度增加其光吸收波段也随之扩大,浓度在5.0 mg/cm^3 以上时对280~400 nm波长范围的紫外线均有良好吸收,总体上 S. compacta 提取物的防晒活性略高于 S. wanannensis 提取物,两者对紫外线的吸收效果均优于阳性对照熊果苷和二苯甲酮, S. compacta 提取物在10.0 mg/cm^3 时对紫外线的吸收效果甚至与阳性对照芦丁相当,显示出较高的防紫外效能;在美白活性方面, S. compacta 和 S. wanannensis 提取物均有一定的抑制酪氨酸酶活性作用, S. compacta 和 S. wanannensis 提取物在此活性无显著性差异;在抗氧化活性方面, S. compacta 和 S. wanannensis 提取物均显示出优异的清除自由基能力,且其活性随浓度的升高而升高,在1.0~5.0 mg/cm^3 浓度下 S. compacta 和 S. wanannensis 提取物的抗氧化活性与阳性对照Vc相当,在10.0 mg/cm^3时 S. wanannensis 提取物的抗氧化活性显著高于 S. compacta 提取物和Vc。研究结果为开发软珊瑚源天然新型化妆品物质奠定了重要基础。
基金2018 National Key Research and Development Plan Project(2018YFC1704100,2018YFC1704103)。
文摘Diabetic retinopathy(DR),as a common microvascular complication of diabetes,is the result of the interaction of multiple factors and multiple mechanisms.Inflammation is one of the important pathophysiological mechanisms of DR.Leukocytes accumulate and adhere to the surface of endothelial cells,glial cell activation and its dysfunction,and the release of vascular endothelial growth factor,interleukin and other inflammatory factors are directly related to the occurrence and development of DR inflammation.Antiinflammation plays an important role in the treatment of DR.Studies have shown that traditional Chinese medicine has a unique advantage in targeting the inflammatory mechanism of DR.Therefore,the inflammatory cells,inflammatory factors and related Chinese medicines closely related to DR are reviewed,in order to provide references for the early prevention and treatment of DR.
