Objective: To investigate the effects and safety of catgut embedding on alleviating insomnia. Methods: Totally 510 patients with insomnia were divided into 5 Chinese medicine(CM) syndrome types: Xin(Heart) and Pi(Sple...Objective: To investigate the effects and safety of catgut embedding on alleviating insomnia. Methods: Totally 510 patients with insomnia were divided into 5 Chinese medicine(CM) syndrome types: Xin(Heart) and Pi(Spleen) deficiency, yin deficiency with excess fire, Xin and gut qi deficiency, Wei(Stomach) disorder, and qi and blood deficiency, respectively. These 5 types of patients were randomly assigned to a catgut embedding group, an acupuncture group or a medication group(30 cases in Xin and Pi deficiency type, Wei disorder type, Xin and gut qi deficiency type, respectively;40 cases in yin deficiency with excess fire type and qi and blood deficiency type, respectively). In the catgut embedding group, patients were treated by implanting catgut into acupoints once every 10 days for a total of 30 days. In the acupuncture group, patients were treated with acupuncture once per day over 30 days(excluding weekends);and patients in the medication group took 1 mg Eurodin Tablet orally every night for 30 days. Pittsburgh Sleep Quality Index(PSQI) was evaluated before treatment, on 30 and 60 days after the first treatment, respectively. The International Unified Sleep Efficiency Value(IUSEV) was measured at 30 and 60 days. The safety was evaluated after treatment and adverse events were analyzed. Results: The objective PSQI scores including subjective sleep quality, sleep latency, sleep duration, habitual sleep efficiency, sleep disturbance, daytime dysfunction, and total scores at 30 days were significantly improved compared with pre-treatment in the catgut embedding and acupuncture groups(P<0.01 or P<0.05). At 30 days, the PSQI scores in catgut embedding group were superior to the medication group in the patients with each type of insomnia, with the exception of sleep duration(P<0.01 or P<0.05). At 60 days, significant differences were found between the catgut embedding group and the medication group(P<0.01 for all indices). The IUSEV scores in the catgut embedding group were significantly higher than the acupuncture group at 60 days, and the scores in acupuncture group were higher than the medication group at 30 days(P<0.05 for all types). No severe adverse events were found in this study. Conclusions: Acupoint catgut embedding and acupuncture were more effective than medication in alleviating insomnia syndrome in different Chinese medicine syndrome type. However, the sustained effects of acupoint catgut embedding were superior to acupuncture.展开更多
Objective:To compare the clinical effects of thick-needle therapy(TNT)and acupuncture therapy(AT)on patients with Bell's palsy(BP)at the recovery stage.Methods:A total of 146 eligible participants from 3 hospitals...Objective:To compare the clinical effects of thick-needle therapy(TNT)and acupuncture therapy(AT)on patients with Bell's palsy(BP)at the recovery stage.Methods:A total of 146 eligible participants from 3 hospitals in China were randomized into the TNT group(73 cases)and the AT group(73 cases)using a central randomization.Both groups received Western medicine thrice a day for 4 weeks.Moreover,patients in the TNT group received subcutaneous insertion of a thick needle into Shendao(GV 11)acupoint,while patients in the AT group received AT at acupoints of Cuanzhu(BL 2),Yangbai(GB 14),Dicang(ST 4),Xiaguan(ST 7),Jiache(ST 6),Yingxiang(LI 20)and Hegu(LI 4),4 times a week,for 4 weeks.Both groups received 2 follow-up visits,which were arranged at 1 month and 3 months after treatment,respectively.The primary outcome measure was House-Brackmann Facial Nerve Grading System(HBFNGS)grade.And the clinical recovery rates of both groups were evaluated according to the HBFNGS grades after treatment.The secondary outcome measures included the facial disability index(FDI)and electroneurogram(EnoG).The adverse events were observed and recorded in both groups.Results:Three cases withdrew from the trial,2 in the TNT group and 1 in the AT group.There was no significant difference in the clinical recovery rates between the TNT and AT groups after 4-week treatment[40.85%(29/71)vs.34.72%(25/72),P>0.05].At the 2nd follow-up visit,more patients in the TNT group showed reduced HBFNGS grades than those in the AT group(P<0.01).No significant difference was observed between the two groups in FDI score,EnoG latency and maximum amplitude ratio at all time points(all P>0.05).Conclusion:The clinical effect of TNT was equivalent to that of AT in patients with BP at recovery stage,while the post-treatment effect of TNT was superior to that of AT.展开更多
基金Supported by Zhejiang Province Science and Technology Hall(No.2011C33004)
文摘Objective: To investigate the effects and safety of catgut embedding on alleviating insomnia. Methods: Totally 510 patients with insomnia were divided into 5 Chinese medicine(CM) syndrome types: Xin(Heart) and Pi(Spleen) deficiency, yin deficiency with excess fire, Xin and gut qi deficiency, Wei(Stomach) disorder, and qi and blood deficiency, respectively. These 5 types of patients were randomly assigned to a catgut embedding group, an acupuncture group or a medication group(30 cases in Xin and Pi deficiency type, Wei disorder type, Xin and gut qi deficiency type, respectively;40 cases in yin deficiency with excess fire type and qi and blood deficiency type, respectively). In the catgut embedding group, patients were treated by implanting catgut into acupoints once every 10 days for a total of 30 days. In the acupuncture group, patients were treated with acupuncture once per day over 30 days(excluding weekends);and patients in the medication group took 1 mg Eurodin Tablet orally every night for 30 days. Pittsburgh Sleep Quality Index(PSQI) was evaluated before treatment, on 30 and 60 days after the first treatment, respectively. The International Unified Sleep Efficiency Value(IUSEV) was measured at 30 and 60 days. The safety was evaluated after treatment and adverse events were analyzed. Results: The objective PSQI scores including subjective sleep quality, sleep latency, sleep duration, habitual sleep efficiency, sleep disturbance, daytime dysfunction, and total scores at 30 days were significantly improved compared with pre-treatment in the catgut embedding and acupuncture groups(P<0.01 or P<0.05). At 30 days, the PSQI scores in catgut embedding group were superior to the medication group in the patients with each type of insomnia, with the exception of sleep duration(P<0.01 or P<0.05). At 60 days, significant differences were found between the catgut embedding group and the medication group(P<0.01 for all indices). The IUSEV scores in the catgut embedding group were significantly higher than the acupuncture group at 60 days, and the scores in acupuncture group were higher than the medication group at 30 days(P<0.05 for all types). No severe adverse events were found in this study. Conclusions: Acupoint catgut embedding and acupuncture were more effective than medication in alleviating insomnia syndrome in different Chinese medicine syndrome type. However, the sustained effects of acupoint catgut embedding were superior to acupuncture.
基金Supported by the Scientific Research Special Fund of Traditional Chinese Medicine Industry(No.201507006-01)。
文摘Objective:To compare the clinical effects of thick-needle therapy(TNT)and acupuncture therapy(AT)on patients with Bell's palsy(BP)at the recovery stage.Methods:A total of 146 eligible participants from 3 hospitals in China were randomized into the TNT group(73 cases)and the AT group(73 cases)using a central randomization.Both groups received Western medicine thrice a day for 4 weeks.Moreover,patients in the TNT group received subcutaneous insertion of a thick needle into Shendao(GV 11)acupoint,while patients in the AT group received AT at acupoints of Cuanzhu(BL 2),Yangbai(GB 14),Dicang(ST 4),Xiaguan(ST 7),Jiache(ST 6),Yingxiang(LI 20)and Hegu(LI 4),4 times a week,for 4 weeks.Both groups received 2 follow-up visits,which were arranged at 1 month and 3 months after treatment,respectively.The primary outcome measure was House-Brackmann Facial Nerve Grading System(HBFNGS)grade.And the clinical recovery rates of both groups were evaluated according to the HBFNGS grades after treatment.The secondary outcome measures included the facial disability index(FDI)and electroneurogram(EnoG).The adverse events were observed and recorded in both groups.Results:Three cases withdrew from the trial,2 in the TNT group and 1 in the AT group.There was no significant difference in the clinical recovery rates between the TNT and AT groups after 4-week treatment[40.85%(29/71)vs.34.72%(25/72),P>0.05].At the 2nd follow-up visit,more patients in the TNT group showed reduced HBFNGS grades than those in the AT group(P<0.01).No significant difference was observed between the two groups in FDI score,EnoG latency and maximum amplitude ratio at all time points(all P>0.05).Conclusion:The clinical effect of TNT was equivalent to that of AT in patients with BP at recovery stage,while the post-treatment effect of TNT was superior to that of AT.
