阐明退役电池的老化行为和衰减机理有助于对其安全高效地再利用。采用容量标定、循环老化、材料表面分析等试验方法对一个近似于盲盒的退役电池系统的老化行为进行了研究。研究结果表明,虽然整个退役电池系统是按照容量衰减到80%的做法...阐明退役电池的老化行为和衰减机理有助于对其安全高效地再利用。采用容量标定、循环老化、材料表面分析等试验方法对一个近似于盲盒的退役电池系统的老化行为进行了研究。研究结果表明,虽然整个退役电池系统是按照容量衰减到80%的做法进行退役,但是退役电池系统中大部分的电池模组健康状态(state of health,SOH)值远远高于80%。选取的一个电池模组在设定的2C倍率、100%放电深度(depth of discharege,DOD)的老化模式下循环到60%SOH以下只有400次,前200次循环衰减较慢,后200次循环衰减较快。材料表面分析结果发现退役电池在循环老化后阳极的劣化要比阴极的更严重,可循环锂的消耗是导致电池容量衰减的主要原因之一。因此,退役电池梯次利用时从模组级别进行分选和成组,可以最大化地挖掘其剩余价值,同时应尽可能在低电流倍率和浅充浅放等较温和工况下使用退役电池。展开更多
帕金森病(parkinson’s disease,PD)是一种目前尚无根治方法的神经系统退行性疾病,主要症状为体位不稳、运动迟缓、僵硬和震颤,这些症状主要是中脑黑质致密部(Substantia nigra pars compacta,SNPC)多巴胺能(Dopaminergic,DAergic)神经...帕金森病(parkinson’s disease,PD)是一种目前尚无根治方法的神经系统退行性疾病,主要症状为体位不稳、运动迟缓、僵硬和震颤,这些症状主要是中脑黑质致密部(Substantia nigra pars compacta,SNPC)多巴胺能(Dopaminergic,DAergic)神经元进行性丢失而引起的,常见于中老年人,给家庭和社会带来沉重的经济负担。PD的具体病因及发病机制尚不明确,目前认为遗传和环境因素间复杂的相互作用可能是帕金森病发病的主要原因。微小RNA在中枢神经系统内不同类型神经元群的发育过程中扮演重要角色,与PD的发生、发展亦有密切联系。本文就微小RNA在帕金森病发病机制中的研究进展进行综述。展开更多
Background Evaluation of left ventricular function plays a vital role in the study of hemodynamics in the circulatory system.This study investigated the feasibility of measuring left ventricular function in rats with ...Background Evaluation of left ventricular function plays a vital role in the study of hemodynamics in the circulatory system.This study investigated the feasibility of measuring left ventricular function in rats with catheterization at the apex of the heart.Methods Left carotid catheterization was used to monitor artery pressure,then right carotid-ventricular catheterization and apical catheterization were orderly performed in 20 SD rats to observe the changes of left heart function.Heart rate,carotid arterial pressure,left ventricular peak pressure,left ventricular end-diastolic pressure were recorded by the biological function experiment system,and differential calculations analyzed the systolic and diastolic rate of left ventricular pressure.Results The peak left ventricular pressure was statistically different between when measured by right carotid-ventricle catheterization and by catheterization at the apex of heart(120.7±14.46 mmHg vs.114.04±12.01 mmHg,P<0.05).There was a significant difference in the carotid artery pressure between when the left ventricular function was measured by right carotid-ventricular catheterization and by apical catheterization(115.6±11.24 mmHg vs.108.07±12.33 mmHg,P<0.05),while a different statistical scenario existed for the maximum increase rate of left ventricular pressure(6197.89±1123.28 mmHg/s vs.5985.92±1342.81 mmHg/s,P>0.05);30 min later,the left ventricular pressure and the maximum increase rate of left ventricular pressure were not significantly different between the first and second measurement measured by catheterization at the apex of heart(114.04±12.01 mmHg vs.112.06±11.26 mmHg,5985.92±1342.81 mmHg/s vs.5700.86±598.97 mmHg/s,P>0.05).However,the maximum decline rate of left ventricular pressure was slightly lower compared with the previous measurement(5231.14±1302.57 mmHg/s vs.4862.72±610.49 mmHg/s,P<0.05).Conclusions It is feasible to evaluate cardiac function in rats by catheterization at the apex of heart,and it is superior to right carotid catheterization for its simpler operation,less bleeding risk,less operation time,and the measurement can be repeatedly conducted at least once.[S Chin J Cardiol 2021;22(1):50-56]展开更多
文摘阐明退役电池的老化行为和衰减机理有助于对其安全高效地再利用。采用容量标定、循环老化、材料表面分析等试验方法对一个近似于盲盒的退役电池系统的老化行为进行了研究。研究结果表明,虽然整个退役电池系统是按照容量衰减到80%的做法进行退役,但是退役电池系统中大部分的电池模组健康状态(state of health,SOH)值远远高于80%。选取的一个电池模组在设定的2C倍率、100%放电深度(depth of discharege,DOD)的老化模式下循环到60%SOH以下只有400次,前200次循环衰减较慢,后200次循环衰减较快。材料表面分析结果发现退役电池在循环老化后阳极的劣化要比阴极的更严重,可循环锂的消耗是导致电池容量衰减的主要原因之一。因此,退役电池梯次利用时从模组级别进行分选和成组,可以最大化地挖掘其剩余价值,同时应尽可能在低电流倍率和浅充浅放等较温和工况下使用退役电池。
文摘帕金森病(parkinson’s disease,PD)是一种目前尚无根治方法的神经系统退行性疾病,主要症状为体位不稳、运动迟缓、僵硬和震颤,这些症状主要是中脑黑质致密部(Substantia nigra pars compacta,SNPC)多巴胺能(Dopaminergic,DAergic)神经元进行性丢失而引起的,常见于中老年人,给家庭和社会带来沉重的经济负担。PD的具体病因及发病机制尚不明确,目前认为遗传和环境因素间复杂的相互作用可能是帕金森病发病的主要原因。微小RNA在中枢神经系统内不同类型神经元群的发育过程中扮演重要角色,与PD的发生、发展亦有密切联系。本文就微小RNA在帕金森病发病机制中的研究进展进行综述。
基金supported by The Open Project of Key Laboratory of Prevention and Treatment of Cardiovascular and Cerebrovascular Diseases,Ministry of Education(No.XN201804)Science and Technology Research Project of Education Department of Jiangxi Province(No.170865)Gannan Medical University Project(No.YB201803)
文摘Background Evaluation of left ventricular function plays a vital role in the study of hemodynamics in the circulatory system.This study investigated the feasibility of measuring left ventricular function in rats with catheterization at the apex of the heart.Methods Left carotid catheterization was used to monitor artery pressure,then right carotid-ventricular catheterization and apical catheterization were orderly performed in 20 SD rats to observe the changes of left heart function.Heart rate,carotid arterial pressure,left ventricular peak pressure,left ventricular end-diastolic pressure were recorded by the biological function experiment system,and differential calculations analyzed the systolic and diastolic rate of left ventricular pressure.Results The peak left ventricular pressure was statistically different between when measured by right carotid-ventricle catheterization and by catheterization at the apex of heart(120.7±14.46 mmHg vs.114.04±12.01 mmHg,P<0.05).There was a significant difference in the carotid artery pressure between when the left ventricular function was measured by right carotid-ventricular catheterization and by apical catheterization(115.6±11.24 mmHg vs.108.07±12.33 mmHg,P<0.05),while a different statistical scenario existed for the maximum increase rate of left ventricular pressure(6197.89±1123.28 mmHg/s vs.5985.92±1342.81 mmHg/s,P>0.05);30 min later,the left ventricular pressure and the maximum increase rate of left ventricular pressure were not significantly different between the first and second measurement measured by catheterization at the apex of heart(114.04±12.01 mmHg vs.112.06±11.26 mmHg,5985.92±1342.81 mmHg/s vs.5700.86±598.97 mmHg/s,P>0.05).However,the maximum decline rate of left ventricular pressure was slightly lower compared with the previous measurement(5231.14±1302.57 mmHg/s vs.4862.72±610.49 mmHg/s,P<0.05).Conclusions It is feasible to evaluate cardiac function in rats by catheterization at the apex of heart,and it is superior to right carotid catheterization for its simpler operation,less bleeding risk,less operation time,and the measurement can be repeatedly conducted at least once.[S Chin J Cardiol 2021;22(1):50-56]
