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Effect of Intravenous Administration of Liposomal Prostaglandin E1 on Microcirculation in Patients with ST Elevation Myocardial Infarction Undergoing Primary Percutaneous Intervention 被引量:27
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作者 Li-Ye Wei Xiang-Hua Fu +4 位作者 Wei Li xi-le bi Shi-Ru Bai Kun Xing Yan-Bo Wang 《Chinese Medical Journal》 SCIE CAS CSCD 2015年第9期1147-1150,共4页
Background:Several studies have demonstrated that primary percutaneous coronary intervention (PCI) can result in reperfusion injury.This study aims to investigate the effectiveness of liposomal prostaglandin E l (... Background:Several studies have demonstrated that primary percutaneous coronary intervention (PCI) can result in reperfusion injury.This study aims to investigate the effectiveness of liposomal prostaglandin E l (Lipo-PGE1,Alprostadil,Beijing Tide Pharmaceutical Co.,Ltd.) for enhancing microcirculation in reperfusion injury.In addition,this study determined the optimal administration method for acute ST elevation myocardial infarction (STEMI) patients undergoing primary PCI.Methods:Totally,68 patients with STEMI were randomly assigned to two groups:intravenous administration ofLipo-PGE 1 (Group A),and no Lipo-PGE1 administration (Group B).The corrected thrombolysis in myocardial infarction (TIMI) frame count (cTFC) and myocardial blush grade (MBG) were calculated.Patients were followed up for 6 months.Major adverse cardiac events (MACE) were also measured.Results:There was no significant difference in the baseline characteristics between the two groups.The cTFC parameter in Group A was significantly lower than Group B (18.06 ± 2.06 vs.25.31 ± 2.59,P < 0.01).The ratio of final MBG grade-3 was significantly higher (P < 0.05) in Group A (87.9%) relative to Group B (65.7%).There was no significant difference between the two groups in final TIMI-3 flow and no-reflow.Patients were followed up for 6 months,and the occurrence of MACE in Group A was significantly lower than that in Group B (6.1% vs.25.9% respectively,P < 0.05).Conclusions:Myocardial microcirculation of reperfusion injury in patients with STEMI,after primary PCI,can be improved by administering Lipo-PGE1. 展开更多
关键词 Intravenous Administration Liposomal Prostaglandin E l Primary Percutaneous Coronary Intervention ST Elevation Myocardial Infarction
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Influence of Puncture Site on Radial Artery Occlusion After Transradial Coronary Intervention 被引量:7
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作者 xi-le bi Xiang-Hua Fu +5 位作者 Xin-Shun Gu Yan-Bo Wang Wei Li Li-Ye Wei Yan-Ming Fan Shi-Ru Bai 《Chinese Medical Journal》 SCIE CAS CSCD 2016年第8期898-902,共5页
Background:The risk of radial artery occlusion (RAO) needs particular attention in transradial intervention (TRI).Therefore,reducing vascular occlusion has an important clinical significance.The aim of this study... Background:The risk of radial artery occlusion (RAO) needs particular attention in transradial intervention (TRI).Therefore,reducing vascular occlusion has an important clinical significance.The aim of this study was to determine the appropriate puncture site during TRI through comparing the occurrence of RAO between the different puncture sites to reduce the occurrence of RAO after TRI.Methods:We prospectively assessed the occurrence of RAO in 606 consecutive patients undergoing TRI.Artery occlusion was evaluated with Doppler ultrasound in 2 days and 1 year after the intervention.Risk factors for RAO were evaluated using a multivariate model analysis.Results:Of the 606 patients,the RAO occurred in 56 patients.Compared with TRI at 2-5 cm away from the radius styloid process,the odds ratio (OR) for occlusion risk at 0 cm and 1 cm were 9.65 (P =0.033) and 8.90 (P =0.040),respectively.The RAO occurred in the ratio of the arterial diameter to the sheath diameter ≤1 (OR =2.45,P =0.004).Conclusion:Distal puncture sites (0-1 cm away from the radius styloid process) can lead to a higher rate of RAO. 展开更多
关键词 Percutaneous Coronary Intervention Puncture Site Radial Artery Risk Factors
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Lessons from transulnar access for repeat percutaneous coronary intervention after radial artery occlusion
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作者 xi-le bi Qing-Sheng Wang 《Chinese Medical Journal》 SCIE CAS CSCD 2020年第12期1497-1498,共2页
To the Editor:An 80-year-old man presented to the Cardiology Department with substernal pain of 20 minutes duration on August 13,2017.We reviewed the patient’s case history record,which included two transradial acces... To the Editor:An 80-year-old man presented to the Cardiology Department with substernal pain of 20 minutes duration on August 13,2017.We reviewed the patient’s case history record,which included two transradial access interventions using 6F sheaths(11-cmlong,Cordis Corporation,FL,USA).On February 13,2009,the patient had presented with an acute inferior wall myocardial infarction and underwent percutaneous coronary intervention(PCI)via the right radial artery.On February 19,2009,the patient underwent a second intervention,also via right radial artery access,for an elective anterior descending branch PCI.The patient ceased smoking after the first PCI.At this admission,before the third intervention,the patient had a weak radial pulse,but his right hand was asymptomatic. 展开更多
关键词 CORONARY ACUTE RADIAL
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