AIM: To investigate the effect of simulated dynamic intraocular pressure (SDIOP) during uncomplicated phacoemulsification on postoperative macular and peripapillary retinal nerve fiber layer (RNFL) thickness. METHODS:...AIM: To investigate the effect of simulated dynamic intraocular pressure (SDIOP) during uncomplicated phacoemulsification on postoperative macular and peripapillary retinal nerve fiber layer (RNFL) thickness. METHODS: Macular and RNFL thicknesses in one eye of patients (n=30) undergoing uncomplicated phacoemulsification were measured by optical coherence tomography preoperatively and 1 week postoperatively. The best-corrected visual acuity, SDIOP, irrigation time (IT), effective phacoemulsification lime, entire surgical duration, blood pressure, and heart rate were recorded. RESULTS: The mean SDIOP and IT was (74.9 +/- 27.4)cmH(2)O and (178.4 +/- 21.6) seconds respectively. We divided our patients into two groups based upon IT with greater than 90cmH(2)O (P>90IT). In Group A (n= 14), the P>90IT was greater than the mean P>90IT, and in Group B (n=16), the P>90IT was less than the mean P>90IT. For all patients there was a significant increase in macular thickness one week after cataract surgery (P=0.001). While the RNFL thickness tended to increase, the change was not significant. The postoperative macular thickness of Group A,(277.8 +/- 13.7)mu m, was significantly thicker than that of Group B, (267.9 +/- 15.0)mu m (P=0.004). The postoperative peripapillary RNFL thickness of Group A, (96.8 +/- 10.8)mu m, was not significantly different from Group B. For Group A, the change in macular thickness was positively correlated with P>90IT (R-2=0.524, P =0.02). There was no statistical difference in postoperative visual acuity between Groups A and B. CONCLUSION: After uncomplicated phacoemulsification, increased macular thickness is associated with the IT under high SDIOP. The effect of high SDIOP is limited to the sub-clinical level.展开更多
基金Supported by Research Grants from Zhejiang Provincial Nature Science Foundation, China(No.Y12H120008)Innovation Guiding Program of the Eye Hospital, Wenzhou Medical College, China (No.YNCX201008)
文摘AIM: To investigate the effect of simulated dynamic intraocular pressure (SDIOP) during uncomplicated phacoemulsification on postoperative macular and peripapillary retinal nerve fiber layer (RNFL) thickness. METHODS: Macular and RNFL thicknesses in one eye of patients (n=30) undergoing uncomplicated phacoemulsification were measured by optical coherence tomography preoperatively and 1 week postoperatively. The best-corrected visual acuity, SDIOP, irrigation time (IT), effective phacoemulsification lime, entire surgical duration, blood pressure, and heart rate were recorded. RESULTS: The mean SDIOP and IT was (74.9 +/- 27.4)cmH(2)O and (178.4 +/- 21.6) seconds respectively. We divided our patients into two groups based upon IT with greater than 90cmH(2)O (P>90IT). In Group A (n= 14), the P>90IT was greater than the mean P>90IT, and in Group B (n=16), the P>90IT was less than the mean P>90IT. For all patients there was a significant increase in macular thickness one week after cataract surgery (P=0.001). While the RNFL thickness tended to increase, the change was not significant. The postoperative macular thickness of Group A,(277.8 +/- 13.7)mu m, was significantly thicker than that of Group B, (267.9 +/- 15.0)mu m (P=0.004). The postoperative peripapillary RNFL thickness of Group A, (96.8 +/- 10.8)mu m, was not significantly different from Group B. For Group A, the change in macular thickness was positively correlated with P>90IT (R-2=0.524, P =0.02). There was no statistical difference in postoperative visual acuity between Groups A and B. CONCLUSION: After uncomplicated phacoemulsification, increased macular thickness is associated with the IT under high SDIOP. The effect of high SDIOP is limited to the sub-clinical level.
