I want to make it very clear at the beginning of this communication;this is a controversial opinion review. However, I believe it is time to rethink our approach to cancer research and therapy. Many cancer researchers...I want to make it very clear at the beginning of this communication;this is a controversial opinion review. However, I believe it is time to rethink our approach to cancer research and therapy. Many cancer researchers, especially those involved in cancer genomic research will disagree. I welcome the disagreement and hope it will stimulate an honest debate and dialog between all disciplines of cancer research and treatment. I am convinced that a vast disconnection exists between those involved in basic research and those in the clinical arena that treat this disease. Cancer researchers in all areas should not ignore the role of cancer metabolism in tumorigenesis, progression and metastasis.展开更多
Mitochondria are evolutionary bacteria that are dynamic intracellular organelles involved in many vital cellular functions. However, modern medicine has fallen prey to misuse and over-usage of antibiotics. This misuse...Mitochondria are evolutionary bacteria that are dynamic intracellular organelles involved in many vital cellular functions. However, modern medicine has fallen prey to misuse and over-usage of antibiotics. This misuse can damage the mitochondrion, alter host antibiotic interactions, and cause serious pathophysiologic conditions. We believe this leads to mitochondrial dysfunction, which may promote tumorigenesis and neurodegeneration. This opinion commentary’s goal is to bring awareness of this important hot topic to the medical community before induced modern plagues are irreversible.展开更多
文摘I want to make it very clear at the beginning of this communication;this is a controversial opinion review. However, I believe it is time to rethink our approach to cancer research and therapy. Many cancer researchers, especially those involved in cancer genomic research will disagree. I welcome the disagreement and hope it will stimulate an honest debate and dialog between all disciplines of cancer research and treatment. I am convinced that a vast disconnection exists between those involved in basic research and those in the clinical arena that treat this disease. Cancer researchers in all areas should not ignore the role of cancer metabolism in tumorigenesis, progression and metastasis.
文摘Mitochondria are evolutionary bacteria that are dynamic intracellular organelles involved in many vital cellular functions. However, modern medicine has fallen prey to misuse and over-usage of antibiotics. This misuse can damage the mitochondrion, alter host antibiotic interactions, and cause serious pathophysiologic conditions. We believe this leads to mitochondrial dysfunction, which may promote tumorigenesis and neurodegeneration. This opinion commentary’s goal is to bring awareness of this important hot topic to the medical community before induced modern plagues are irreversible.
