Background:Fujian Province has one of the highest reported incidences of hepatitis B virus infection in China.This study aimed to provide a theoretical framework for preventing and controlling hepatitis B in Fujian Pr...Background:Fujian Province has one of the highest reported incidences of hepatitis B virus infection in China.This study aimed to provide a theoretical framework for preventing and controlling hepatitis B in Fujian Province,and to assess the trends and the spatial-temporal distribution patterns of hepatitis B in this region.Methods:Data on hepatitis B cases were extracted from the National Notifiable Infectious Disease Surveillance System.Spatial autocorrelation analysis,trend surface analysis,and spatial-temporal scanning statistics were used to identify the spatial and aggregation patterns at the county level.The Joinpoint was used to assess the reported incidence trends.Results:The average reported incidence of hepatitis B in Fujian from 2012 to 2021 was 14.46/10,000 population,with 583,262 notified cases.The age-adjusted reported incidence of hepatitis B decreased from 17.44/10,000 population in 2012 to 11.88/10,000 population in 2021,with an average reduction in the annual percentage change of 4.5%.There were obvious spatial-temporal aggregation characteristics in hepatitis B cases,and a high-incidence area was located in eastern Fujian.Spatio-temporal scanning statistics revealed four levels of aggregation of hepatitis B reporting rates.The first level of aggregation area included Minhou,Gulou,Jin’an,Taijiang,and nine other districts and counties.Conclusions:The incidence of hepatitis B is declining in Fujian Province.Spatial clusters of hepatitis B cases in Fujian Province were identified,and high-risk areas in eastern Fujian still exist.Closely monitoring the gen-eral patterns in the occurrence of hepatitis B and implementing focused control and preventative strategies are important.展开更多
基金supported by the Fujian Research and Training Grants for Young and Middle-aged Leaders in Healthcare.
文摘Background:Fujian Province has one of the highest reported incidences of hepatitis B virus infection in China.This study aimed to provide a theoretical framework for preventing and controlling hepatitis B in Fujian Province,and to assess the trends and the spatial-temporal distribution patterns of hepatitis B in this region.Methods:Data on hepatitis B cases were extracted from the National Notifiable Infectious Disease Surveillance System.Spatial autocorrelation analysis,trend surface analysis,and spatial-temporal scanning statistics were used to identify the spatial and aggregation patterns at the county level.The Joinpoint was used to assess the reported incidence trends.Results:The average reported incidence of hepatitis B in Fujian from 2012 to 2021 was 14.46/10,000 population,with 583,262 notified cases.The age-adjusted reported incidence of hepatitis B decreased from 17.44/10,000 population in 2012 to 11.88/10,000 population in 2021,with an average reduction in the annual percentage change of 4.5%.There were obvious spatial-temporal aggregation characteristics in hepatitis B cases,and a high-incidence area was located in eastern Fujian.Spatio-temporal scanning statistics revealed four levels of aggregation of hepatitis B reporting rates.The first level of aggregation area included Minhou,Gulou,Jin’an,Taijiang,and nine other districts and counties.Conclusions:The incidence of hepatitis B is declining in Fujian Province.Spatial clusters of hepatitis B cases in Fujian Province were identified,and high-risk areas in eastern Fujian still exist.Closely monitoring the gen-eral patterns in the occurrence of hepatitis B and implementing focused control and preventative strategies are important.
